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Full-Text Articles in Dentistry
Osteogenic Differentiation Of Adipose-Derived Mesenchymal Stem Cells Using 3d-Printed Pdlla/ Β-Tcp Nanocomposite Scaffolds, Ashkan Bigham, Amir Hamed Aghajanian, Mehdi Movahedi, Mansoureh Sattary, Mohammad Rafienia, Lobat Tayebi
Osteogenic Differentiation Of Adipose-Derived Mesenchymal Stem Cells Using 3d-Printed Pdlla/ Β-Tcp Nanocomposite Scaffolds, Ashkan Bigham, Amir Hamed Aghajanian, Mehdi Movahedi, Mansoureh Sattary, Mohammad Rafienia, Lobat Tayebi
School of Dentistry Faculty Research and Publications
Designing bone scaffolds containing both organic and inorganic composites simulating the architecture of the bone is the most important principle in bone tissue engineering. The objective of this study was to fabricate a composite scaffold containing poly (D, l)-lactide (PDLLA) and β-tricalcium phosphate (β-TCP) as a platform for osteogenic differentiation of adipose-derived mesenchymal stem cells. In this study, PDLLA/β-TCP scaffolds were fabricated using three-dimensional printing (3D) technology through melt excursion technique. The physicomechanical characteristics, including microstructure, mechanical properties, of the customized scaffolds were investigated. Further, the in vitro biological characteristics of manufactured scaffolds were evaluated in conjugation with buccal fat …