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Articles 1 - 10 of 10
Full-Text Articles in Dentistry
Oral Microbiome And Gingival Tissue Apoptosis And Autophagy Transcriptomics, Jeffrey L. Ebersole, Sreenatha S. Kirakodu, Elliot Neumann, Luis Orraca, Janis Gonzalez Martinez, Octavio A. Gonzalez
Oral Microbiome And Gingival Tissue Apoptosis And Autophagy Transcriptomics, Jeffrey L. Ebersole, Sreenatha S. Kirakodu, Elliot Neumann, Luis Orraca, Janis Gonzalez Martinez, Octavio A. Gonzalez
Dental Medicine Faculty Publications
Objective: This study focused on documenting characteristics of the gingival transcriptome during various stages of periodontitis targeting genes associated with apoptotic and autophagic pathways and changes that specifically associate with features of the oral microbiome. Methods: Macaca mulatta (n = 18; 12-23 years) were examined at baseline and 0.5, 1, and 3 months of disease progression, as well as 5 months with clinical disease resolution. 16S sequencing and microarray analyses examined changes in the microbiome and gingival transcriptome, respectively, at each time point from every animal. Results: Specific patterns of apoptotic and autophagic genes were identified related to the initiation …
The Impact Of Impression Coping Geometrical Design On Accuracy Of Implant Impressions: An Experimental Study, Motaz Osman Osman, Neamat Hassan Abubakr, Ahmed Suliman, Hassan Ziada
The Impact Of Impression Coping Geometrical Design On Accuracy Of Implant Impressions: An Experimental Study, Motaz Osman Osman, Neamat Hassan Abubakr, Ahmed Suliman, Hassan Ziada
Dental Medicine Faculty Publications
Aim This in vitro study aimed to evaluate the effect of implant impression coping geometrical designs on the accuracy of open and closed impression techniques and in the parallel and nonparallel implant positions. Material and methods Three custom-made acrylic resin models of three tested implant systems (Straumann (R), SIC Invent (R), and Osstem (R)) with diverse coping geometrical designs were evaluated in simulated cases of two parallel and two nonparallel implants. The horizontal and vertical discrepancies were measured and analyzed. Results No statistically significant differences between the two impression techniques in either parallel or nonparallel implants were observed. The high …
Prevalence Of Hyperdontia, Hypodontia, And Concomitant Hypo-Hyperdontia, Nareh Eshgian, Tanya Al-Talib, Stanley Nelson, Neamat Hassan Abubakr
Prevalence Of Hyperdontia, Hypodontia, And Concomitant Hypo-Hyperdontia, Nareh Eshgian, Tanya Al-Talib, Stanley Nelson, Neamat Hassan Abubakr
Dental Medicine Faculty Publications
Background/purpose: Anomalies in human dentition are some of the most common occurrences of congenital abnormalities. Present study aimed to determine the prevalence of hypodontia, hyperdontia and concomitant hypo-hyperdontia (CHH) among patients attending the University of Nevada, Las Vegas (UNLV) School of Dental Medicine clinics. Materials and methods: Retrospective search was conducted on patients’ clinical notes in AxiUm. Search included using keywords such as “hypodontia”, “hyperdontia”, “supernumerary teeth” and “congenitally missing”. Panoramic radiographs were used to confirm the hyperdontia, hypodontia or CHH for patients attending the UNLV SDM clinics from 2010 to 2018. Collected data were analyzed using the chi-square test. …
Mir-365 (Microrna): Potnetial Biomarker In Oral Squamous Cell Carcinoma Exosomes And Extracellular Vesicles, Jeffery Coon, Karl Kingsley, Katherine M. Howard
Mir-365 (Microrna): Potnetial Biomarker In Oral Squamous Cell Carcinoma Exosomes And Extracellular Vesicles, Jeffery Coon, Karl Kingsley, Katherine M. Howard
Dental Medicine Faculty Publications
Introduction: miR-365 is a non-coding microRNA that regulates transcription and has been demonstrated to promote oncogenesis and metastasis in some cancers, while suppressing these effects in others. Many microRNAs are produced and then exported extracellularly in exosomes, which are small extracellular vesicles ranging from 30 to 100 nm that are found in eukaryotic fluids and facilitate many cellular functions. Exosomes and extracellular vesicles are produced by many cell types, including oral cancer cells—although no study to date has evaluated miR-365 and oral cancer exosomes or extracellular vesicles. Based on this information, our research question was to evaluate whether oral cancers …
Comparison Of Dna Extracted From Pediatric Saliva, Gingival Crevicular Fluid And Site-Specific Biofilm Samples, Jason Emett, Roxanne David, Jaydene Mcdaniel, Steven Mcdaniel, Karl Kingsley
Comparison Of Dna Extracted From Pediatric Saliva, Gingival Crevicular Fluid And Site-Specific Biofilm Samples, Jason Emett, Roxanne David, Jaydene Mcdaniel, Steven Mcdaniel, Karl Kingsley
Dental Medicine Faculty Publications
(1) Introduction: Due to the non-invasive nature of saliva, many methods have been used to isolate and collect DNA from saliva samples for microbial screening. Many oral microbes also inhabit the oral biofilm, which may represent significantly different microbial constituents that may contribute to oral health and disease, including caries and periodontal disorders. Moreover, the biofilm may vary within the same patient at different sites. Few studies have evaluated the comparison between DNA isolated from saliva and DNA from site-specific biofilm, with virtually no studies addressing this analysis among pediatric patients. (2) Methods: An existing repository of paper point derived …
Human Papillomavirus (Hpv) Vaccine Knowledge, Awareness And Acceptance Among Dental Students And Post-Graduate Dental Residents, Steve Kent Mann, Karl Kingsley
Human Papillomavirus (Hpv) Vaccine Knowledge, Awareness And Acceptance Among Dental Students And Post-Graduate Dental Residents, Steve Kent Mann, Karl Kingsley
Dental Medicine Faculty Publications
Introduction: The recent development of a vaccine that is highly effective against the human papillomavirus (HPV) has been met with widespread clinical and public health professional acceptance. However, social and societal barriers to vaccination may hamper public health efforts to prevent HPV-mediated diseases. Although a few studies have evaluated knowledge or awareness of HPV vaccination among dentists or dental educators, few studies have evaluated the acceptance, knowledge and awareness of HPV vaccination among dental students and post-graduate dental residents. The primary goal of this study is to evaluate survey responses regarding acceptance, knowledge and awareness of HPV vaccination among dental …
Craniofacial Analysis May Indicate Co-Occurrence Of Skeletal Malocclusions And Associated Risks In Development Of Cleft Lip And Palate, Denise K. Liberton, Payal Verma, Konstantinia Almpani, Peter W. Fung, Rashmi Mishra, Snehlata Oberoi, Figen Ç. Şenel, James K. Mah, John Huang, Bonnie L. Padwa, Janice S. Lee
Craniofacial Analysis May Indicate Co-Occurrence Of Skeletal Malocclusions And Associated Risks In Development Of Cleft Lip And Palate, Denise K. Liberton, Payal Verma, Konstantinia Almpani, Peter W. Fung, Rashmi Mishra, Snehlata Oberoi, Figen Ç. Şenel, James K. Mah, John Huang, Bonnie L. Padwa, Janice S. Lee
Dental Medicine Faculty Publications
Non-syndromic orofacial clefts encompass a range of morphological changes affecting the oral cavity and the craniofacial skeleton, of which the genetic and epigenetic etiologic factors remain largely unknown. The objective of this study is to explore the contribution of underlying dentofacial deformities (also known as skeletal malocclusions) in the craniofacial morphology of non-syndromic cleft lip and palate patients (nsCLP). For that purpose, geometric morphometric analysis was performed using full skull cone beam computed tomography (CBCT) images of patients with nsCLP (n = 30), normocephalic controls (n = 60), as well as to sex- and ethnicity- matched patients with an equivalent …
Adea‐Adee Shaping The Future Of Dental Education Iii: Assessment In Competency‐Based Dental Education: Ways Forward, Ingrid Tonni, Cynthia C. Gadbury-Amyot, Marjan Govaerts, Olle Ten Cate, Joan Davis, Lily T. Garcia, Richard W. Valachovic
Adea‐Adee Shaping The Future Of Dental Education Iii: Assessment In Competency‐Based Dental Education: Ways Forward, Ingrid Tonni, Cynthia C. Gadbury-Amyot, Marjan Govaerts, Olle Ten Cate, Joan Davis, Lily T. Garcia, Richard W. Valachovic
Dental Medicine Faculty Publications
Assessment in competency-based dental education continues to be a recognized area for growth and development within dental programs around the world. At the joint American Dental Education Association (ADEA) and the Association for Dental Education in Europe (ADEE) 2019 conference, Shaping the Future of Dental Education III, the workshop on assessment was designed to continue the discussion started in 2017 at the ADEA-ADEE Shaping the Future of Dental Education II.1 The focus of the 2019 conference involved examining the potential of entrustable professional activities (EPAs) and current thinking about workplace-based assessment (WBA) within competency-based education in the 21st century. Approximately …
Adea-Adee Shaping The Future Of Dental Education Iii: Engaging With Global Networking To Enable Global Oral Health, Upen S. Patel, Lior Shapira, Jennifer E. Gallagher, Joan Davis, Lily T. Garcia, Richard W. Valachovic
Adea-Adee Shaping The Future Of Dental Education Iii: Engaging With Global Networking To Enable Global Oral Health, Upen S. Patel, Lior Shapira, Jennifer E. Gallagher, Joan Davis, Lily T. Garcia, Richard W. Valachovic
Dental Medicine Faculty Publications
Global networking has been identified as an important method of enhancing health care education and services in the field of dentistry.1 The ability to share expertise, resources, knowledge, and experience to benefit all is highly desired among students, educators, health care professionals, and communities globally. Both our student and patient populations are dynamic societies that are becoming increasingly complex and facing growing needs and expectations, which is a constant challenge for educators and health care professionals to satisfy.2 The key question, stemming from the Global Networking (GN) workshop of the 2017 ADEE‐ADEA Shaping the Future of Dental Education II meeting, …
Comprehensive Review Of Current Endodontic Sealers, Takashi Komabayashi, David Colmenar, Nicholas Cvach, Aparna Bhat, Carolyn Primus, Yohji Imai
Comprehensive Review Of Current Endodontic Sealers, Takashi Komabayashi, David Colmenar, Nicholas Cvach, Aparna Bhat, Carolyn Primus, Yohji Imai
Dental Medicine Faculty Publications
Endodontic sealers for non-surgical root canal treatment (NSRCT) span many compositions and attributes. This comprehensive review discusses current types of endodontic sealers by their setting reaction type, composition, and properties: zinc oxide-eugenol, salicylate, fatty acid, glass ionomer, silicone, epoxy resin, tricalcium silicate, and methacrylate resin sealers. Setting time, solubility, sealing ability, antimicrobial, biocompatibility, and cytotoxicity are all aspects key to the performance of endodontic sealers. Because sealing ability is so important to successful outcomes, the relative degree of microleakage among all the relevant sealers was calculated by way of a meta-analysis of relevant literature. Compared to AH Plus, tricalcium silicate …