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Full-Text Articles in Dentistry

The Role Of Nod-Like Receptors In Innate Immunity, Cassio Luiz Coutinho Almeida-Da-Silva, Luiz Eduardo Baggio Savio, Robson Coutinho-Silva, David M. Ojcius Mar 2023

The Role Of Nod-Like Receptors In Innate Immunity, Cassio Luiz Coutinho Almeida-Da-Silva, Luiz Eduardo Baggio Savio, Robson Coutinho-Silva, David M. Ojcius

All Dugoni School of Dentistry Faculty Articles

The innate immune system in vertebrates and invertebrates relies on conserved receptors and ligands, and pathways that can rapidly initiate the host response against microbial infection and other sources of stress and danger. Research into the family of NOD-like receptors (NLRs) has blossomed over the past two decades, with much being learned about the ligands and conditions that stimulate the NLRs and the outcomes of NLR activation in cells and animals. The NLRs play key roles in diverse functions, ranging from transcription of MHC molecules to initiation of inflammation. Some NLRs are activated directly by their ligands, while other ligands …


Interactions Between Silica And Titanium Nanoparticles And Oral And Gastrointestinal Epithelia: Consequences For Inflammatory Diseases And Cancer, Cassio Luiz Coutinho Almeida-Da-Silva, Leticia Ferreira Cabido, Wei Chun Chin, Ge Wang, David M. Ojcius, Changqing Li Mar 2023

Interactions Between Silica And Titanium Nanoparticles And Oral And Gastrointestinal Epithelia: Consequences For Inflammatory Diseases And Cancer, Cassio Luiz Coutinho Almeida-Da-Silva, Leticia Ferreira Cabido, Wei Chun Chin, Ge Wang, David M. Ojcius, Changqing Li

All Dugoni School of Dentistry Faculty Articles

Engineered nanoparticles (NPs) composed of elements such as silica and titanium, smaller than 100 nm in diameter and their aggregates, are found in consumer products such as cosmetics, food, antimicrobials and drug delivery systems, and oral health products such as toothpaste and dental materials. They may also interact accidently with epithelial tissues in the intestines and oral cavity, where they can aggregate into larger particles and induce inflammation through pathways such as inflammasome activation. Persistent inflammation can lead to precancerous lesions. Both the particles and lesions are difficult to detect in biopsies, especially in clinical settings that screen large numbers …


Pharmacology For National Board Examination, Krina Shah Jan 2023

Pharmacology For National Board Examination, Krina Shah

Dugoni School of Dentistry Student Scholarly Works

This pharmacology study guide is designed to provide students preparing for the National Boards exam with a clear and concise visual aid in the form of systemic flow charts. Each flow chart is organized by drug class and includes information on the mechanism of action, indications, contraindications, dosages, and common adverse effects for each drug within the class. By using this study guide, students can easily navigate through the complex world of pharmacology and feel confident in their ability to succeed on the pharmacology section of the National Board exam. The study guide for pharmacology is significant in several ways. …


Medical Marijuana Knowledge And Attitudes: A Survey Of Dental And Dental Hygiene Faculty And Students, Dara Szyliowicz, Andrew Young, Yesha Golwala Jan 2023

Medical Marijuana Knowledge And Attitudes: A Survey Of Dental And Dental Hygiene Faculty And Students, Dara Szyliowicz, Andrew Young, Yesha Golwala

Eberhardt School of Business Faculty Datasets

Background:

Medical Marijuana (MM) use is increasing, requiring healthcare professionals, such as dentists, to possess a working knowledge of MM. Previous studies have indicated that MM education is lacking in current healthcare education.

Methods:

A 50-question survey was created to assess, in detail, dental and dental hygiene faculty and students knowledge, practice, and attitudes toward MM, and to identify possible correlations between responses. The survey was modeled after a previous survey conducted amongst practicing pharmacists. All faculty dentists, faculty dental hygienists, students and residents at the Arthur A. Dugoni School of Dentistry, University of the Pacific, were invited by email …


A Flash Of Inspiration: Enhancing Dental Student Drug Recognition, Benjamin D. Zeitlin Jan 2023

A Flash Of Inspiration: Enhancing Dental Student Drug Recognition, Benjamin D. Zeitlin

All Dugoni School of Dentistry Faculty Articles

Students preparing for exams often retain the complexities of a subject but instant recognition and recall is something that, for most, takes time and consistent, repeated study to establish. This can happen through well-managed spaced learning (iterative study) prior to examination; given the preponderance of massed study (cramming for a subject),1 however, many students require long-term exposure in the clinic to patients’ medical histories to achieve instant recall. Understanding the applied pharmacology of common drugs is a current American Dental Association accreditation standard. Ideally, dental students should demonstrate a consistent level of basic drug recognition and the ability to retrieve …