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Neural Crest Contributions To Dental Pulp Stem/Progenitor Cells And Craniofacial Structures: Alveolar Processes, Tongue And Temporomandibular Joint, Vinay Jain
Theses and Dissertations (ETD)
Background: The cranial neural crest, a transient embryonic structure in vertebrates, is crucial to craniofacial and dental development. Populations of multipotent stem cells have been identified in various dental tissues including dental pulp. Hence, identification of multipotent cells of neural crest lineage within dental pulp and delineation of neural crest contributions to various craniofacial tissues may be a step towards utilizing the potential of neural crest progenitor cells for therapeutic applications.
Objective: The overall purpose of the study was to identify a population of dental pulp stem/progenitor cells of neural crest lineage and demonstrate their neural differential potential and to …