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Full-Text Articles in Dentistry
A Comparison Of Traditional Orthodontic Polishing Systems With Composite Polishing Systems Following Orthodontic Debonding, Elizabeth A. Melvin, Qingzhao Yu, Xiaoming Xu, Camille G. Laird, Paul C. Armbruster, Richard W. Ballard
A Comparison Of Traditional Orthodontic Polishing Systems With Composite Polishing Systems Following Orthodontic Debonding, Elizabeth A. Melvin, Qingzhao Yu, Xiaoming Xu, Camille G. Laird, Paul C. Armbruster, Richard W. Ballard
School of Public Health Faculty Publications
Introduction: At the completion of treatment, the orthodontic practitioner's goal is to effectively remove all traces of adhesive and return enamel to its initial state. With the advent of new polishing systems being released each year, there may be one product that is superior to others. Aim: The purpose of this study is to determine the efficacy of new polishing systems (in the last 5–10 years) used in general dentistry on enamel surface roughness following debond utilizing profilometery and scanning electron microscopy and compare them to established orthodontic polishing systems results. Methods: Fifty-two mandibular incisors were randomly assigned to one …
A Small Molecule Produced By Lactobacillus Species Blocks Candida Albicans Filamentation By Inhibiting A Dyrk1-Family Kinase, Jessie Macalpine, Martin Daniel-Ivad, Zhongle Liu, Junko Yano, Nicole M. Revie, Robert T. Todd, Peter J. Stogios, Hiram Sanchez, Teresa R. O’Meara, Thomas A. Tompkins, Alexei Savchenko, Anna Selmecki, Amanda O. Veri, David R. Andes, Paul L. Fidel, Nicole Robbins, Justin Nodwell, Luke Whitesell, Leah E. Cowen
A Small Molecule Produced By Lactobacillus Species Blocks Candida Albicans Filamentation By Inhibiting A Dyrk1-Family Kinase, Jessie Macalpine, Martin Daniel-Ivad, Zhongle Liu, Junko Yano, Nicole M. Revie, Robert T. Todd, Peter J. Stogios, Hiram Sanchez, Teresa R. O’Meara, Thomas A. Tompkins, Alexei Savchenko, Anna Selmecki, Amanda O. Veri, David R. Andes, Paul L. Fidel, Nicole Robbins, Justin Nodwell, Luke Whitesell, Leah E. Cowen
School of Dentistry Faculty Publications
The fungus Candida albicans is an opportunistic pathogen that can exploit imbalances in microbiome composition to invade its human host, causing pathologies ranging from vaginal candidiasis to fungal sepsis. Bacteria of the genus Lactobacillus are colonizers of human mucosa and can produce compounds with bioactivity against C. albicans. Here, we show that some Lactobacillus species produce a small molecule under laboratory conditions that blocks the C. albicans yeast-to-filament transition, an important virulence trait. It remains unexplored whether the compound is produced in the context of the human host. Bioassay-guided fractionation of Lactobacillus-conditioned medium linked this activity to 1-acetyl-β-carboline (1-ABC). We …
Leukotrienes Are Dispensable For Vaginal Neutrophil Recruitment As Part Of The Immunopathological Response During Experimental Vulvovaginal Candidiasis, Junko Yano, David J. White, Anthony P. Sampson, Floyd L. Wormley, Paul L. Fidel
Leukotrienes Are Dispensable For Vaginal Neutrophil Recruitment As Part Of The Immunopathological Response During Experimental Vulvovaginal Candidiasis, Junko Yano, David J. White, Anthony P. Sampson, Floyd L. Wormley, Paul L. Fidel
School of Dentistry Faculty Publications
Recruitment of polymorphonuclear neutrophils (PMNs) into the vaginal lumen is the hallmark of an acute immunopathologic inflammatory response during vulvovaginal candidiasis (VVC) caused by Candida albicans. Recurrent VVC (RVVC) remains a chronic health burden in affected women worldwide despite the use of antifungal therapy. Based on the role leukotrienes (LTs) play in promoting inflammation, leukotriene receptor antagonists (LTRAs) targeted for LTB4 (etalocib) or LTC4, LTD4, and LTE4 (zafirlukast or montelukast) have been shown to reduce inflammation of epithelial tissues. An open-label pilot study using long-term regimens of zafirlukast in women with RVVC indicated the potential for some relief from recurrent …
A Comparison Of Shear Bond Strength Of Brackets Bonded To Zirconia, Hannah Knott, Xiaoming Xu, Edwin Kee, Qingzhao Yu, Paul Armbruster, Richard Ballard
A Comparison Of Shear Bond Strength Of Brackets Bonded To Zirconia, Hannah Knott, Xiaoming Xu, Edwin Kee, Qingzhao Yu, Paul Armbruster, Richard Ballard
School of Dentistry Faculty Publications
Purpose: The objective of this study was to compare the shear bond strength (SBS) of ceramic orthodontic brackets bonded to highly translucent zirconia surfaces following the use of two different primers. Materials and methods: Three types of highly translucent zirconia crowns, Cercon xt ML, e.max ZirCAD, and STML-ML Katana Zirconia, were milled, sandblasted, and primed using two zirconia primers, Monobond Etch and Prime and Z-Prime Plus. A ceramic bracket (Radiance) was bonded onto the facial surface of each crown. Shear bond strength was evaluated using a universal testing machine. Results: There was no significant overall difference across the six experimental …
A Retrospective Cross-Sectional Study Of The Effect Of Liposomal Bupivacaine On Postoperative Opioid Prescribing After Third Molar Extraction, Stuart E. Lieblich, Dale Misiek, John Olczak, Heidi Fleck, Fanta Waterman
A Retrospective Cross-Sectional Study Of The Effect Of Liposomal Bupivacaine On Postoperative Opioid Prescribing After Third Molar Extraction, Stuart E. Lieblich, Dale Misiek, John Olczak, Heidi Fleck, Fanta Waterman
School of Dentistry Faculty Publications
Purpose: Reducing opioid prescriptions after third molar extraction may decrease the risk of opioid dependence. This study compared prescribed morphine milligram equivalents (MMEs) in patients undergoing mandibular third molar removal with and without use of liposomal bupivacaine (LB). Methods: This retrospective cross-sectional study included deidentified data from electronic medical records of patients who underwent extraction of ≥1 partial bony—or full bony—impacted mandibular third molar at 2 oral surgery centers in the United States in 2012 or 2018. The primary predictor variable was use of LB 133 mg. The primary outcome variable was total prescribed opioids in MMEs. The secondary outcome …
Streptococcus Mutans Lacking Sufcdsub Is Viable, But Displays Major Defects In Growth, Stress Tolerance Responses And Biofilm Formation, Kassapa Ellepola, Xiaochang Huang, Ryan P. Riley, Jacob P. Bitoun, Zezhang Tom Wen
Streptococcus Mutans Lacking Sufcdsub Is Viable, But Displays Major Defects In Growth, Stress Tolerance Responses And Biofilm Formation, Kassapa Ellepola, Xiaochang Huang, Ryan P. Riley, Jacob P. Bitoun, Zezhang Tom Wen
School of Dentistry Faculty Publications
Streptococcus mutans appears to possess a sole iron-sulfur (Fe-S) cluster biosynthesis system encoded by the sufCDSUB cluster. This study was designed to examine the role of sufCDSUB in S. mutans physiology. Allelic exchange mutants deficient of the whole sufCDSUB cluster and in individual genes were constructed. Compared to the wild-type, UA159, the sufCDSUB-deficient mutant, Δsuf::kanr, had a significantly reduced growth rate, especially in medium with the absence of isoleucine, leucine or glutamate/glutamine, amino acids that require Fe-S clusters for biosynthesis and when grown with medium adjusted to pH 6.0 and under oxidative and nitrosative stress conditions. Relative to UA159, Δsuf::kanr …
Does Alcohol Consumption Protect Against Late Dental Implant Failures?, Brian R. Carr, William J. Boggess, John F. Coburn, Peter Rekawek, Sung Kiang Chuang, Neeraj Panchal, Brian P. Ford
Does Alcohol Consumption Protect Against Late Dental Implant Failures?, Brian R. Carr, William J. Boggess, John F. Coburn, Peter Rekawek, Sung Kiang Chuang, Neeraj Panchal, Brian P. Ford
School of Dentistry Faculty Publications
Purpose: Social factors have been implicated in the development of peri-implant pathologies, including implant failure. This study aims to investigate whether alcohol consumption affects late dental implant failures. Methods: A retrospective cohort study evaluated implants placed between 2006 and 2012 at the Philadelphia Veterans Affairs Medical Center. The primary predictor variable was alcohol consumption, measured as nonconsumption and mild, moderate, and heavy consumption. The primary outcome variable was late dental implant failure. Univariate, bivariate, and multivariate statistics were applied, with P <.05 used to define statistical significance. Results: Our cohort consisted of 103 patients and 295 implants with a 5-year minimum follow-up. Most patients were male (93%) with an average age of 60 at the time of implant placement. Late implant failure was associated with 30 implants. Compared to nonconsumption, mild consumption was associated with a 75% decrease in late implant failure (P =.0494), moderate consumption was associated with a 60% decrease (P =.3826), and heavy consumption was associated with a 200% increase (P <.1782). Compared to mild consumption, heavy consumption was associated with an 847% increase in late failure (P =.0135). Conclusions: Results from this retrospective cohort analysis suggest that mild alcohol consumption is associated with a decrease in late dental implant failures.
Immediate And Early Loading Of Hydrothermally Treated, Hydroxyapatite-Coated Dental Implants: A 7-Year Prospective Randomized Clinical Study, Afarin Arghami, David Simmons, Jeanne St Germain, Pooja Maney
Immediate And Early Loading Of Hydrothermally Treated, Hydroxyapatite-Coated Dental Implants: A 7-Year Prospective Randomized Clinical Study, Afarin Arghami, David Simmons, Jeanne St Germain, Pooja Maney
School of Dentistry Faculty Publications
Background Existing research on marginal bone stability around hydroxyapatite (HA)-coated implants often lacks adequate long-term follow-up. The purpose of this randomized prospective study was to evaluate the 7-year outcome of patients with immediate and early loaded single-tooth restorations supported by implants with plasma-sprayed, partially HA-coated surfaces. Forty-two patients in need of 50 single implants were treated in in the Postgraduate Periodontics Clinic of Louisiana State University School of Dentistry. Implants were randomly divided into 2 groups: Group A was immediately loaded, and Group B was early loaded. Continuous follow-up with periodic maintenance care and radiographic evaluations was performed. The primary …
Does Supplemental Regional Anesthesia Decrease Length Of Stay And Opioid Use For Patients Undergoing Head And Neck Microvascular Reconstruction?, Earl Peter Park, John Minh Le, Jordan Gigliotti, Joel Feinstein, Yedeh P. Ying, Anthony B. Morlandt
Does Supplemental Regional Anesthesia Decrease Length Of Stay And Opioid Use For Patients Undergoing Head And Neck Microvascular Reconstruction?, Earl Peter Park, John Minh Le, Jordan Gigliotti, Joel Feinstein, Yedeh P. Ying, Anthony B. Morlandt
School of Dentistry Faculty Publications
Purpose: The purpose of this study was to compare length of hospital stay and opioid usage among head and neck surgery (HNS) patients treated with and without regional anesthesia for microvascular free-flap donor sites. Methods: The authors performed a retrospective cohort study for HNS patients undergoing microvascular free-flap reconstruction. The control group received no regional anesthesia. The experimental group had a regional anesthesia nerve block performed immediately before surgery. The primary outcome variable was length of stay, and the secondary outcome variable was total morphine milliequivalents. The data were analyzed using Student t tests, analysis of variance, Mann-Whitney U test, …