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Full-Text Articles in Dentistry
Oral Health Inequalities In Adolescents And Young Adults In Ontario, Maria Rahman
Oral Health Inequalities In Adolescents And Young Adults In Ontario, Maria Rahman
Electronic Thesis and Dissertation Repository
Oral health is consistently linked to physiological, psychological, and social aspects of well-being in adolescents and young adults. In this thesis, I aimed to examine the social determinants of oral health and dental care utilization. First, I conducted a scoping review of the literature, demonstrated the multifaceted nature of oral health and its connections to broader social and economic factors. Then, I conducted a cross-sectional analysis of the Canadian Community Health Survey which showed a social gradient in oral health and dental care utilization among adolescents and young adults in Ontario. When stratified by age, there was a protective association …
The Impact Of Access To Oral Health Care On Inadequate Oral Health And Multimorbidity, Luis Limo
The Impact Of Access To Oral Health Care On Inadequate Oral Health And Multimorbidity, Luis Limo
Electronic Thesis and Dissertation Repository
The connection between oral health and other non-communicable chronic conditions—commonly referred in the dental literature as the oral-systemic health connection—emphasizes the role of oral health care on both oral diseases and chronic conditions, particularly in vulnerable populations like the elderly. This thesis comprises 2 studies: the first is a systematic review on the impact of oral health care interventions, as an indicator of access to oral health care, on chronic conditions of which their co-existence would result in multimorbidity; the second study is a cross-sectional investigation of the associations between oral health, access to oral health care, and multimorbidity among …
Validation Study On The Differentiation Of Human Periodontal Ligament Cells In The Presence Of Cementum Protein 1 And Periostin, Deborah A. O'Reilly
Validation Study On The Differentiation Of Human Periodontal Ligament Cells In The Presence Of Cementum Protein 1 And Periostin, Deborah A. O'Reilly
Electronic Thesis and Dissertation Repository
Existing research alludes to the fact that human periodontal ligament cells differentiate into an ossifying phenotype in response to differential gene expression during orthodontic tooth movement. The purpose of this research was to validate the differentiation of human periodontal ligament cells of young individuals in the presence of specific proteins and stimuli (cementum protein, periostin and osteogenic media), which mimic the environment of the periodontal ligament. Another objective was to assess the differential gene expression within these cells under the same conditions. A protocol was developed to provide a collagen-protein scaffold on which human periodontal ligament cells were maintained for …
Characterizing Human Papillomavirus Associated Oral Epithelial Dysplasia, Damir Rosic
Characterizing Human Papillomavirus Associated Oral Epithelial Dysplasia, Damir Rosic
Electronic Thesis and Dissertation Repository
The role of high-risk human papillomavirus (HR-HPV) is well documented in oropharyngeal squamous cell carcinoma and cervical cancer. Although a subset of oral dysplastic lesions have been associated to HPV infection as well, there is currently limited data characterizing these lesions. We identified HPV-associated oral epithelial dysplasia (HPV-OED) through screening for histopathological features of HPV and p16INK4a immunoreactivity. Transcriptionally active infections were confirmed by performing RT-qPCR to identify E6 mRNA expression. We identified 82 cases of confirmed HPV-OED that showed a strong predilection for male patients and anatomical sites such as floor of mouth and ventral tongue. This group had …