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Full-Text Articles in Dentistry

Promoting Mammography Screenings In African American Women: Media, Church, And Health Providers, Lasonya Little, Debra C. Wallace, K.Jay Poole Nov 2023

Promoting Mammography Screenings In African American Women: Media, Church, And Health Providers, Lasonya Little, Debra C. Wallace, K.Jay Poole

Journal of Health Disparities Research and Practice

Due to the underutilization of screening mammography, African American women (AAW) are more likely to experience negative health outcomes after receiving a late-stage breast cancer diagnosis than White Women (WW). The purpose of this article is to examine the roles of the media, health community and the African American church and pastor and their potential impact in AAW screening decisions. Fifteen AAW, ages 45 and older, were invited to participate in a semi-structured interview. Most women agreed the African American pastor and church as well as the health community, and media are an integral part of their lives. Therefore, specific …


Oral Prevalence Of Akkermancia Muciniphila Among Pediatric And Adult Orthodontic And Non-Orthodontic Patients, Ching Shen May 2023

Oral Prevalence Of Akkermancia Muciniphila Among Pediatric And Adult Orthodontic And Non-Orthodontic Patients, Ching Shen

UNLV Theses, Dissertations, Professional Papers, and Capstones

Akkermansia muciniphila (AM) is one of many highly abundant intestinal microbes that influences homeostasis and metabolic disorders and may also play a role in oral disorders. However, there is little evidence regarding the oral prevalence of this organism. Based upon this lack of evidence, the primary goal of this project is to survey an existing saliva repository to determine the overall prevalence of this organism and any associations with demographic or patient characteristics (age, sex, body mass index, race/ethnicity, orthodontic therapy). Using an approved protocol, a total n = 141 pediatric samples from an existing saliva repository were screened using …


Chemotherapeutic Drug Resistance Associated With Differential Mirna Expression Of Mir-375 And Mir-27 Among Oral Cancer Cell Lines, Kieran Huni May 2023

Chemotherapeutic Drug Resistance Associated With Differential Mirna Expression Of Mir-375 And Mir-27 Among Oral Cancer Cell Lines, Kieran Huni

UNLV Theses, Dissertations, Professional Papers, and Capstones

Objective: Although progress has been made towards the identification of molecular profiles that influence oral cancer growth and metastasis, recent advances have suggested that non-coding microRNAs (such as miR-21, miR-27, miR-145, miR-155, miR-365, miR-375 and miR-494) may be involved in multiple aspects of chemotherapeutic responsiveness. Based upon the paucity of information regarding this phenomenon, this project will determine whether these specific microRNAs are correlated with oral cancer responsiveness to chemotherapies, including Paclitaxel, Cisplatin and Fluorouracil (5FU).Methods: Commercially available and well-characterized oral squamous cell carcinoma cell lines (SCC4, SCC9, SCC15, SCC25 and CAL27) were used for this study. Experimental 96-well assays …


Differential Effects Of Extracellular Matrix Glycoproteins Fibronectin And Laminin-5 On Dental Pulp Stem Cell Phenotypes And Responsiveness, Hyungbin Lee May 2023

Differential Effects Of Extracellular Matrix Glycoproteins Fibronectin And Laminin-5 On Dental Pulp Stem Cell Phenotypes And Responsiveness, Hyungbin Lee

UNLV Theses, Dissertations, Professional Papers, and Capstones

Dental pulp stem cells (DPSCs) are mesenchymal stem cells (MSCs) with the potential to differentiate in a limited number of other tissue types. Some evidence has suggested the modulation of DPSC growth may be mediated, in part, by exogenous extracellular matrix (ECM) glycoproteins, including fibronectin (FN) and laminin-5 (LN5). Although preliminary research suggests that some ECM glycoproteins may work as functional biomaterials to modulate DPSC growth responses, the primary goal of this project is to determine the specific effects of FN and LN5 on DPSC growth and viability.Using an existing DPSC repository, n = 16 DPSC isolates were cultured and …


Dental Pulp Stem Cell Differentiation Potential Of Bmp-2 And Bmp-4, David Li May 2023

Dental Pulp Stem Cell Differentiation Potential Of Bmp-2 And Bmp-4, David Li

UNLV Theses, Dissertations, Professional Papers, and Capstones

Introduction: Many studies are now evaluating the potential for dental pulp stem cells (DPSC) to assist with more complex and biotechnology applications, such as facilitating and promoting osseointegration following dental implants. However, the effects of factors that may control osseointegration and bone repair using DPSC including bone morphogenic proteins (BMP-2, BMP-4) are not yet well understood.Objective: Based upon this lack of evidence, the primary goal of this project is to evaluate the potential effects of BMPs (alone or in combination with other growth factors) to induce factors associated with osteogenesis. Methods: DPSC isolates from an existing repository (n = 13) …


Advancing Health Equity In The Us Military, James D. Mancuso, John Young, Jennifer Rusiecki, Shauna Stahlman, Natasha Schvey, Toya Randolph, Candy Wilson, Catherine Witkop, Patrick Hyde, Althea Green, Patcho Santiago, Donald Shell, Tracy Sbrocco Mar 2023

Advancing Health Equity In The Us Military, James D. Mancuso, John Young, Jennifer Rusiecki, Shauna Stahlman, Natasha Schvey, Toya Randolph, Candy Wilson, Catherine Witkop, Patrick Hyde, Althea Green, Patcho Santiago, Donald Shell, Tracy Sbrocco

Journal of Health Disparities Research and Practice

Eliminating health disparities and achieving health equity are central to US national health objectives and the Military Health System’s “quadruple aim,” which has readiness as its core aim. Because military service members enjoy universal eligibility for health care, it is sometimes assumed that health disparities do not exist in the Department of Defense (DoD). However, while some studies have shown that disparities have been attenuated or eliminated in the DoD, others suggest that significant disparities remain. Reasons these disparities may remain include that universal eligibility for care does not necessarily result in equal to access to care, and that equal …