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Full-Text Articles in Dentistry
Induction Of S100a7 Expression From Mechanical Stress-Induced Human Dental Pulp Cells And Its Effect On Osteoclastogenesis, Hataichanok Charoenpong
Induction Of S100a7 Expression From Mechanical Stress-Induced Human Dental Pulp Cells And Its Effect On Osteoclastogenesis, Hataichanok Charoenpong
Chulalongkorn University Theses and Dissertations (Chula ETD)
Mechanical injuries of dental pulp tissues could lead to root resorption by osteoclast/odontoclast. S100A7 has been demonstrated to involve in inflammatory processes and potentially involved in bone destruction. However, the roles of S100A7 in dental pulp have not been reported. Therefore, this this study aimed to investigate the effect of mechanical stress on S100A7 expression in human dental pulp cells (hDPCs) and to investigate the effect of S100A7 protein on osteoclast differentiation. HDPCs were stimulated with in vitro compressive loading. Cell viability was determined using MTT assay. Real-time PCR (qPCR) and ELISA were utilized to determine the mRNA and protein …
The Application Of Prostacyclin In Promoting Angiogenesis Of Dental Pulp Tissue In A Three Dimensional Organ Culture System, Sonntana Seang
The Application Of Prostacyclin In Promoting Angiogenesis Of Dental Pulp Tissue In A Three Dimensional Organ Culture System, Sonntana Seang
Chulalongkorn University Theses and Dissertations (Chula ETD)
Background: Dental pulp vitality can be threatened by carious or iatrogenic exposure that can lead to pulp tissue loss. The formation of a vascular network is crucial to provide a suitable environment for tissue regeneration. Thus, promoting angiogenesis is essential for successful pulpal repair in regenerative endodontics therapy. Iloprost, a prostacyclin analog, promotes vascularization in several organs such as, heart, lung, and corneal. Previously, it has been demonstrated that, iloprost induced pulpal blood flow and enhanced dentin formation in a rat mechanical pulp exposure model. However, the angiogenic effect of iloprost on the human dental pulp vasculature remains unknown. Objective: …
Differential Dendritic Cell Responses To Candida Species, Thu Nguyen Ngoc
Differential Dendritic Cell Responses To Candida Species, Thu Nguyen Ngoc
Chulalongkorn University Theses and Dissertations (Chula ETD)
Mannan in the outermost layer of Candida cell wall may be the first molecules that interact with host dendritic cells (DCs) and activate immune responses that determine disease outcomes. However, little is known how different mannan structures of common Candida species affect DC activation and T cell responses. Thus, this work compared the effects of mannans of Candida albicans, Candida tropicalis, Candida glabrata, Candida krusei, Candida parapsilosis and Candida dubliniensis on bone marrow-derived DC (BMDC) responses in mice. C. albicans and C. tropicalis mannan could not activate DC maturation, however, they induced IFN-gamma production which consequently provoked Th1 responses. C. …