Dentistry Commons^™

Cost-Effectiveness Of [99mtc]Tilmanocept Relative To [99mtc]Sulfur Colloid For Sentinel Lymph Node Biopsy In Early Stage Oral Cavity Cancer, Karen Y Choi, Qiang Hao, Kathryn Carlisle, Christopher S Hollenbeak, Stephen Y Lai

Student and Faculty Publications

BACKGROUND: Several studies have demonstrated varying rates of efficacy, reliability, and sensitivity of sentinel lymph node biopsy (SLNB) in identifying occult nodal disease for early stage oral cavity squamous cell carcinoma (OCSCC) depending on the radionuclide agent utilized. No head-to-head comparison of cost or clinical outcomes of SLNB when utilizing [99mTc]tilmanocept versus [99mTc]sulfur colloid has been performed. The goal of this study was to develop a decision model to compare the cost-effectiveness of [99mTc]tilmanocept versus [99mTc]sulfur colloid in early stage OCSCC.

PATIENTS AND METHODS: A decision model of disease and treatment as a function of SLNB was created. Patients with …

The Mechanisms Of Nerve Injury Caused By Viral Infection In The Occurrence Of Gastrointestinal Motility Disorder-Related Diseases, Yaqian Li, Qiuyu Chen, Liwei Wang, Xin Chen, Bangmao Wang, Weilong Zhong

Student and Faculty Publications

Gastrointestinal motility refers to the peristalsis and contractility of gastrointestinal muscles, including the force and frequency of gastrointestinal muscle contraction. Gastrointestinal motility maintains the normal digestive function of the human body and is a critical component of the physiological function of the digestive tract. At present, gastrointestinal motility disorder-related diseases are gradually affecting human production and life. In recent years, it has been consistently reported that the enteric nervous system has a coordinating and controlling role in gastrointestinal motility. Motility disorders are closely related to functional or anatomical changes in the gastrointestinal nervous system. At the same time, some viral …

Natural Remedies To Combat Aberrant Hallmark Signatures Including Altered Glycosylation In Oral Carcinoma, Kruti A. Mehta, Jayendra B. Patel, Prabhudas S. Patel

Research Symposium

Background: Tobacco associated oral cancers remain a major concern in India with higher incidence and mortality making it an Indian-centric burning issue. To combat this dreadful disease, we investigated effects of certain natural compounds on the hallmark signatures including glycosylation transcripts levels in oral carcinoma.

Methods: The tongue carcinoma cells- SAS cells were treated with tobacco compounds, natural compounds and Cisplatin. RNA was isolated from the cells and converted to cDNA. RT-qPCR was performed to evaluate expression levels of various genes.

Results: The treatment of tobacco compounds resulted in similar pattern of altered makers (ST3GAL1, NEU3, FUT5, FUT6, MMP2, BCL2) …

Epigenome-Wide Association Study Using Peripheral Blood Leukocytes Identifies Genomic Regions Associated With Periodontal Disease And Edentulism In The Atherosclerosis Risk In Communities Study, Naisi Zhao, Flavia Teles, Jiayun Lu, Devin C Koestler, James Beck, Eric Boerwinkle, Jan Bressler, Karl T Kelsey, Elizabeth A Platz, Dominique S Michaud

Student and Faculty Publications

AIM: To investigate individual susceptibility to periodontitis by conducting an epigenome-wide association study using peripheral blood.

MATERIALS AND METHODS: We included 1077 African American and 457 European American participants of the Atherosclerosis Risk in Communities (ARIC) study who had completed a dental examination or reported being edentulous at Visit 4 and had available data on DNA methylation from Visit 2 or 3. DNA methylation levels were compared by periodontal disease severity and edentulism through discovery analyses and subsequent testing of individual CpGs.

RESULTS: Our discovery analysis replicated findings from a previous study reporting a region in gene ZFP57 (6p22.1) that …

The Impact Of Access To Oral Health Care On Inadequate Oral Health And Multimorbidity, Luis Limo

Electronic Thesis and Dissertation Repository

The connection between oral health and other non-communicable chronic conditions—commonly referred in the dental literature as the oral-systemic health connection—emphasizes the role of oral health care on both oral diseases and chronic conditions, particularly in vulnerable populations like the elderly. This thesis comprises 2 studies: the first is a systematic review on the impact of oral health care interventions, as an indicator of access to oral health care, on chronic conditions of which their co-existence would result in multimorbidity; the second study is a cross-sectional investigation of the associations between oral health, access to oral health care, and multimorbidity among …

Effects Of Surface Treatment Method Forming New Nano/Micro Hierarchical Structures On Attachment And Proliferation Of Osteoblast-Like Cells, Jae-Seung Im, Hyunsuk Choi, Hyun-Wook An, Tae-Yub Kwon, Min-Ho Hong

Student and Faculty Publications

Titanium (Ti) and Ti-based alloys are commonly used in dental implants, and surface modifications of dental implants are important for achieving osseointegration (i.e., direct connection between the implant surface and bone). This study investigated the effect of an eco-friendly etching solution-a hydrogen peroxide-sodium bicarbonate mixture-on the surface properties and contact angles of osteoblast adhesion and proliferation on Ti surfaces. Disk-shaped Ti specimens were prepared using different surface treatments (machining, sandblasting, and sandblasting/acid-etching), and they were immersed in the etching solution and ultrasonically cleaned. Surface characterization was performed using scanning electron microscopy, digital microscopy, contact angle analysis, and X-ray photoelectron spectroscopy. …

Evaluation Of The Clinical And Radiographic Effectiveness Of Treating Peri-Implant Bone Defects With A New Biphasic Calcium Phosphate Bone Graft: A Prospective, Multicenter Randomized Controlled Trial, Jae-Hong Lee, Hyun-Wook An, Jae-Seung Im, Woo-Joo Kim, Dong-Won Lee, Jeong-Ho Yun

Student and Faculty Publications

PURPOSE: Biphasic calcium phosphate (BCP), a widely used biomaterial for bone regeneration, contains synthetic hydroxyapatite (HA) and β-tricalcium phosphate (β-TCP), the ratio of which can be adjusted to modulate the rate of degradation. The aim of this study was to evaluate the clinical and radiographic benefits of reconstructing peri-implant bone defects with a newly developed BCP consisting of 40% β-TCP and 60% HA compared to demineralized bovine bone mineral (DBBM).

METHODS: This prospective, multicenter, parallel, single-blind randomized controlled trial was conducted at the periodontology departments of 3 different dental hospitals. Changes in clinical (defect width and height) and radiographic (augmented …

Impacts Of A Duf2207 Family Protein On Streptococcus Mutans Stress Tolerance Responses And Biofilm Formation, Xiaochang Huang, Camile G. Laird, Paul P. Riley, Zezhang Tom Wen

School of Dentistry Faculty Publications

Locus SMU.243 in Streptococcus mutans was annotated as a member of the DUF2207 family proteins highly conserved in all bacteria but with unknown function. To investigate its role in S. mutans physiology, a SMU.243-deficient mutant was constructed using allelic exchange mutagenesis, and the impacts of SMU.243 deletion on bacterial growth, stress tolerance response, and biofilm formation were analyzed. Compared to the wild-type UA159, S. mutans lacking SMU.243 displayed a reduced growth rate and a reduced overnight culture density (p < 0.01) when grown at low pH and in the presence of methyl viologen. Relative to the parent strain, the deficient mutant also had a reduced survival rate following incubation in a buffer of pH 2.8 (p < 0.01) and in a buffer containing hydrogen peroxide at 58 mM after 60 min (p < 0.001) and had a reduced capacity in biofilm formation especially in the presence of sucrose (p < 0.01). To study any ensuing functional/phenotypical links between SMU.243 and uppP, which is located immediately downstream of SMU.243 and encodes an undecaprenyl pyrophosphate phosphatase involved in recycling of carrier lipid undecaprenyl phosphate, a uppP deficient mutant was generated using allelic exchange mutagenesis. Unlike the SMU.243 mutant, deletion of uppP affected cell envelope biogenesis and caused major increases in susceptibility to bacitracin. In addition, two variant morphological mutants, one forming rough colonies and the other forming mucoid, smooth colonies, also emerged following the deletion of uppP. The results suggest that the SMU.243-encoded protein of the DUF2207 family in S. mutans plays an important role in stress tolerance response and biofilm formation, but unlike the downstream uppP, does not seem to be involved in cell envelope biogenesis, although the exact roles in S. mutans’ physiology awaits further investigation.

Comparison Of Different Reconstruction Flap For Maxillofacial Region: An Original Research., Pallavi Khan Chakraborty, Smit Patel, Misbah Farheen Mulla, Manisha Mangesh Kulkarni, Rummaan Ahmed Sheikh, Anuj Kishor Shukla

Student and Faculty Publications

INTRODUCTION: Large chunks of the tissue are sacrificed during the surgical procedures for the treatment if oral cancers. Our goal was to assess the viability of "

MATERIAL AND METHODS: Sixty subjects were included in this investigation, and they were divided into 3 groups. The follow-up as accompanied for six months. Comparisons were made for the time for the operations, reduction in the width of the mouth opening and the survival rates of the flaps. The data that was collected for the above two parameters and compared for the significance using the

RESULTS: In the subjects with the PM, the …

Assessment Of The Apical Transportation And Quantity Of Root Canal Dentin Removed Using Different New Rotary File Systems: An Original Study, Harmeet Singh, Anuj K Shukla, Apurva A Jadhav, Anshuman Shetty, Chitharanjan Shetty, Smita D Dutta, Mohammed Mustafa

Student and Faculty Publications

INTRODUCTION: The rotary systems have found a common application in the clinical practice for the endodontic therapies. Hence, we compared three recent endodontic systems for the comparison of the dentine removal and the apical transportation particularly in the curved canals.

METHODS: Oneshape, Pro Taper Next, and Edgefile X3 were the three systems that were compared. Thirty maxillary mesio buccal canals of the human permanent teeth were compared due to its curved nature. The volume of dentin removed and apical transportation (mm) were measured using micro-computed tomographic imaging (mm). Both the coronal section and the entire canal length had their dentin …

Immediate Implant Placement Simultaneously With Ridge Augmentation In The Maxillary Esthetic Region Using Allograft Versus Autogenous Bone Rings, Mithaq A. Nasser, Nesma M. El- Gohary, Mai A. Haggag, Wael M. Ahmed

Mansoura Journal of Dentistry

Objective: To evaluate allogeneic versus autogenous bone rings (harvested from the chin) for ridge augmentation the of maxillary esthetic zone simultaneously with implant placement. Materials and Methods: This randomized clinical trial included 14 patients who were seeking implant rehabilitation of partially edentulous atrophic ridge the in the esthetic zone. The patients were randomly and equally divided into two groups; immediate implants were placed simultaneously with each autogenous bone ring from chin group I (control group) and, with allogenic bone ring group II (study group). The evaluation was done immediately (T0), postoperatively at 1 month (T1), at 3 months (T3), and …

Single Soft Tissue Support Versus Dual Tooth-Tissue Support For Clasp-Less Mesial Implant Retained Mandibular Class I Rpd: Cross-Over Clinical Study, Aisha Z. Mostafa

Mansoura Journal of Dentistry

Objective: To evaluate the single soft tissue support versus dual tooth-tissue support for mesial implant retained RPD. Materials and Methods: This clinical cross-over study included 10 partially edentulous patients with the only remaining mandibular six anterior teeth. Every patient received two mandibular implants at the 1st premolar region. Two mandibular implants' retained partial overdentures were constructed with two different support concepts, two different designs, opposing a maxillary single denture. One of the dentures was done with a design based mainly on soft tissue support but the other denture was done with a dual tooth-tissue support design. The effects of each …

A 3d Perfusable Platform For In Vitro Culture Of Patient Derived Xenografts, Lindsey K Sablatura, Kristin M Bircsak, Peter Shepherd, Madhavi Bathina, Karla Queiroz, Mary C Farach-Carson, Rick A Kittles, Pamela E Constantinou, Anthony Saleh, Nora M Navone, Daniel A Harrington

Student and Faculty Publications

Many advanced cancer models, such as patient-derived xenografts (PDXs), offer significant benefits in their preservation of the native tumor's heterogeneity and susceptibility to treatments, but face significant barriers to use in their reliance on a rodent host for propagation and screening. PDXs remain difficult to implement in vitro, particularly in configurations that enable both detailed cellular analysis and high-throughput screening (HTS). Complex multilineage co-cultures with stromal fibroblasts, endothelium, and other cellular and structural components of the tumor microenvironment (TME) further complicate ex vivo implementation. Herein, the culture of multiple prostate cancer (PCa)-derived PDX models as 3D clusters within engineered biomimetic …

Effect Of Titanium Tetrafluoride On Degree Of Conversion And Bond Strength Of An Orthodontic Primer, Omnia M. Khalifa, Manal F. Badawi, Tarek A. Soliman

Mansoura Journal of Dentistry

Objective: To evaluate the degree of conversion (DC), and orthodontic bracket shear bond strength (SBS) after the incorporation of 3 wt.% TiF4 into an orthodontic primer. Materials and Methods: According to the concentration of TiF4 within the orthodontic primer, there were two groups: the control (TF0C) and experimental groups (TF3C) (0&3 wt.% TiF4 respectively). The DC was evaluated for each group using FTIR. Ten orthodontic brackets were bonded using each concentration to the clean and etched enamel buccal surface. The SBS test was performed in an Instron universal testing machine, using a chisel positioned at the junction interface with a …

Evaluation Of Antimicrobial Efficiency Of Herbal Irrigants Of Pulpectomized Primary Teeth, Hanaa M. Shalan

Mansoura Journal of Dentistry

Objective: This study aimed to evaluate the antimicrobial efficiency of 2 herbal extracts versus 2.5% sodium hypochlorite and saline in eliminating Enterococcus faecalis (E. faecalis) bacteria within infected primary root canals. Materials and Methods: Forty roots of extracted lower primary molars were obtained and divided into 4 groups according to the type of irrigant: Group 1 (control) NaOCl 2.5%, Group 2 (12.5% turmeric irrigant), and Group 3 (25% propolis irrigant) and Group 4 (saline). Root canals were contaminated with E. faecalis bacteria. Bacterial counts were performed from samples that were taken from each canal pre-irrigation and post-irrigation. Data was analyzed …

Effect Of Different Implants Number And Distributions Used To Assist Mandibular Complete Overdenture: A Study Of Bite, Eslam Helmi, Elsayed Abdelkhalek, Ahmed Habib

Mansoura Journal of Dentistry

Objective: This within-patient study aimed to evaluate the influence of different numbers and distribution of implants used to assist mandibular complete overdenture on a patient's maximum biting force and masticatory efficiency. Materials and Methods: Six healthy completely edentulous patients were selected for this study. Each patient received a conventional complete denture then four implants were installed in the canine and premolar areas bilaterally. The implants were delayed loaded by mandibular overdenture using locator attachments, patients were classified into Group I: anterior two implants loaded by the overdenture; Group II: posterior two implants loaded by the overdenture; and Group III: four …

Adaptation Of Different Milled Post Materials With Flared Root Canals, Ahmed Y. Abdo, Walid A. Al-Zordk, Amal A. Sakrana

Mansoura Journal of Dentistry

Objective: To evaluate the internal adaptation of different milled post materials using microcomputed tomography.Materials and Methods: Forty mandibular first premolar teeth were distributed into four equal groups (n=10). Three groups in which different milled post materials were used in widely flared root canals: group CV; Custom made Vita Enamic posts, group CP; Custom made PEKK posts, group CF; Custom made fiber posts and one group in which ready-made fiber posts were used in normal root canal (group RF). All teeth received root canal treatment and were sectioned 1.5 mm above the cemento-enamel junction. The gutta-percha was removed from the root …

Screw Retained Implant Supported Zirconia Anterior Fixed Dental Prosthesis With Different Abutment Angulations: Evaluation Of Fracture Resistance And Failure Modes, Mohamed H. Mohamed, Walid A. Al-Zordk, Nesma El-Gohary, Mohamed H. Ghazy

Mansoura Journal of Dentistry

Objective: To evaluate the effect of different implant-abutment angulations on the fracture resistance of anterior three-unit implant-supported zirconia fixed dental prosthesis. Materials and Methods: Five groups (n=10) were fabricated to represent maxillary anterior three-unit zirconia fixed dental prosthesis supported by two implants with different implant-abutment angulations including group 0o-0o, group 0o-17.5o, group 0o-35o, group 17.5o-17.5o and group 35o-35o. Zirconia FDPs were cemented by self-adhesive resin cement. All specimens were subjected to thermocycling (5000 X 5oC/55oC) and mechanical loading (50 N X 120,000 cycles /1.6Hz). Static loading was applied using the universal testing machine at a crosshead speed of 1 mm/min. …

Evaluation Of Cuspal Deflection Of Fiber Reinforcing Composite Application Techniques Using Measuroscope, Mohamed H. Elkholy, Fatma A. Elerian, Hamdi H. Hamama, Hanan A. Hegazi

Mansoura Journal of Dentistry

Objective: To evaluate cuspal deflection of mesio-occluso-distal (MOD) cavities restored with short fiber-reinforced composite. Materials and Methods: Two different commercially available composite resin restorations; short fiber-reinforced (ever X Posterior GC, Tokyo Japan) and conventional micro-hybrid (G-aenial universal resin composite GC, Tokyo Japan) resin composite restorative material bonded with a universal adhesive (G-Premio BOND GC, Tokyo Japan) were used in the current study. A total of 40 sound maxillary human premolars were selected for the cuspal deflection test and received standardized MOD cavity preparations suitable for each test. The sample was divided into four groups; Group A: conventional microhybrid resin composite …

Potential Effect Of Different Pulp Capping Materials On Human Dental Pulp Stem Cells: A Laboratory Study, Mohamed A. Bedir, Laila Amin, Essam Soussa

Mansoura Journal of Dentistry

Objective: This study aimed to evaluate the regenerative capacity of two different pulp capping materials TheraCal LC and Nano hydroxyapatite on stem cells extracted from the human dental pulp as a treatment modality for pulp capping. Materials and Methods: Human dental pulp stem cells were obtained and characterized. They were prepared in 12-well plates, cultured in standard culture media, and separated into three groups with 12 each. The first group served as the negative control group and contained only human dental pulp stem cells; the second group contained TheraCal LC, which was incubated with human dental pulp stem cells; and …

Marginal Fit Of Veneers Made From Different Lithium Disilicate Cad/Cam Materials, Sara R. Khouri, Maged M. Zohdy, Ghada Abd El Fattah

Mansoura Journal of Dentistry

Objective: To assess the degree of marginal adaptation of CAD/CAM milled veneers from three different lithium disilicate materials: Upcera Lithium Disilicate CAD, Rosetta SM Lithium Disilicate CAD, and Ivoclar IPS e.max CAD, with a marginal thickness of 0.3mm. Materials and Methods: Twenty-four laminate veneers were milled from lithium disilicate blocks (IPS e.max, Upcera, and Rosetta SM) with a marginal thickness of 0.3mm using a CAD/CAM milling machine (Sirona Cerec MCXL), each group of materials consists of 8 veneers and were cemented to duplicated epoxy dies then a digital microscope was used to assess the marginal adaptation. Results: For cervical surfaces, …

Ferrule Effect On Fracture Resistance Of Endodontically Treated Teeth Restored With Two Esthetic Post And Core Materials Fabricated With Different Techniques, Mohamed W. Abdullah, Amina M. Hamdy, Ghada Abdelfattah

Mansoura Journal of Dentistry

Objective: Assessment of ferrule effect on fracture resistance of Customized fiber post and Custom-made PEEK post with a core. Materials and Methods: 28 single-rooted mandibular premolars with approximate similarity in shape and size and no cracks or caries were selected for this study. The length of the root was measured from the root apex to the middle point of the cementoenamel junction in the labial surface; it was about (16±1 mm). Teeth were divided into two groups, each group contained 14 teeth, with a ferrule group and without a ferrule group followed by coronal decapitation of all samples. Endodontic treatment …

Fracture Resistance Of Molars With Class Ii Mod Cavities Restored With Cad/Cam Ceramic Onlays: Impact Of Deep Marginal Elevation, Ali I. Alqurshi, Ali A. Elkaffas, Salah H. Mahmoud

Mansoura Journal of Dentistry

Objective: This study evaluated the effect of deep marginal elevation (DME) using an ion-releasing material, resin-modified glass ionomer, and nano-hybrid flowable composite on the fracture resistance of molars with Class II MOD cavities restored with CAD/CAM ceramic onlays. Materials and Methods: Fifty molar teeth were randomly assigned to one of five groups (n=10/group): Enamel (EN), Cementum (CE), Cention forte (CF), Tetric-N flow (TF), and Resin modified glass ionomer (RM) groups. Specimens were prepared for a standard MOD cavity with margins located 2 mm below the CEJ for CF, RM, TF, and CE groups, while the EN group had margins located …

Head And Neck Tumor Histopathological Image Representation With Pre- Trained Convolutional Neural Network And Vision Transformer, Ranny Rahaningrum Herdiantoputri, Daisuke Komura, Tohru Ikeda, Shumpei Ishikawa

Journal of Dentistry Indonesia

Image representation via machine learning is an approach to quantitatively represent histopathological images of head and neck tumors for future applications of artificial intelligence-assisted pathological diagnosis systems. Objective: This study compares image representations produced by a pre-trained convolutional neural network (VGG16) to those produced by a vision transformer (ViT-L/14) in terms of the classification performance of head and neck tumors. Methods: W hole-slide images of five oral t umor categories (n = 319 cases) were analyzed. Image patches were created from manually annotated regions at 4096, 2048, and 1024 pixels and rescaled to 256 pixels. Image representations were …

Independent Effects Of Hiv And Antiretroviral Therapy On The Oral Microbiome Identified By Multivariate Analyses, Clifford J. Beall, Elizabeth A. Lilly, Carolina Granada, Kelly Treas, Kenneth R. Dubois, Shahr B. Hashmi, Jose A. Vazquez, Michael E. Hagensee, Ann L. Griffen, Eugene J. Leys, Paul L. Fidel

School of Dentistry Faculty Publications

The oral microbiome is an important predictor of health and disease. We recently reported significant yet modest effects of HIV under highly active antiretroviral therapy (ART) on the oral microbiome (bacterial and fungal) in a large cohort of HIV-positive (HIV+) and matched HIV-negative (HIV-) individuals. As it was unclear whether ART added to or masked further effects of HIV on the oral microbiome, the present study aimed to analyze the effects of HIV and ART independently, which also included HIV- subjects on preexposure prophylaxis (PrEP) therapy. Cross-sectional analyses of the effect of HIV devoid of ART (HIV+ ART- versus matched …

Oral Health In Relation To The Covid-19 Pandemic, Anika L. Gram

Honors Thesis

Oral health has seen significant changes through the Covid-19 pandemic. Many people experienced the lifestyle alteration of wearing a mask for a major portion of their day-to-day life, and some went to the dentist significantly less than they did pre-pandemic. The literature review explores dental practices during the Covid-19 pandemic. It also examines mask-wearing behaviors both before and during the pandemic and the research that has been conducted previously regarding the potential effects of mask-wearing. Despite the decrease in use of masks post-pandemic, many healthcare professionals continue to wear masks daily. Additionally, in the event of future disease outbreak, it …

Methacrylate Versus Ormocer - Based Composites: Impact Of Preheating On Repair Bond Strength, Aya M. El Said, Asmaa A. Mohamed, Ashraf I. Ali, Salah H. Mahmoud

Mansoura Journal of Dentistry

Objective: To evaluate and compare the impact of preheating on the repair bond strength of Methacrylate and Ormocerbased composite. Materials and Methods: A total number of 24 standardized cuboid composite blocks were fabricatedwith the aid of teflon split mold (25×4×4) mm dimensions. Half of these composite blocks were made from a universalnanohybrid methacrylate-based composite and the other half was made from a universal nanohybrid Ormocer based.The top surfaces of all mounted specimens were surface treated with sandblasting, silane coupling agents, and universaladhesive of the same brand of composite. Four cylindrical composite rods (2 mm height, 3 mm internal diameter) werebuilt …

Comparative Evaluation Of Microleakage Of Different Class V Cavity Preparation Restored With Composite In Primary Molars: An In Vitro Study, Henar E. Elsayed, Ibrahim H. El Kalla, Hossam E. Hammouda

Mansoura Journal of Dentistry

Objective: To compare the effect of the cavity design and the location of the gingival wall, onenamel and cementum on the microleakage of Class V composite resin restorations in primary molars. Materialsand Methods: Class V cavity was made on the buccal surface of sixty sound primary mandibular second molar inthis study. The teeth were divided into two main groups: Group A (Kidney shaped cavity) and Group B (Rectangleshaped cavity). Each group was also subdivided into two subgroups, Subgroup A1; Kidney shape with gingivalmargin on enamel, Subgroup A2; Kidney shape with gingival margin on cementum, Subgroup B1; Rectangle shapewith gingival margin …

Evaluation Of Surface Roughness, Water Sorption, And Solubility Of Glass Ionomer Restorative Cement Incorporated With Different Antibiotics, Wafaa S. Ahmed, Essam E. Al-Wakeel, Enas T. Enan, Noha A. El-Wassefy

Mansoura Journal of Dentistry

Objective: To evaluate the influence of adding different antibiotics to glass ionomer cement (GIC) on its surfaceroughness, water sorption, and solubility. Materials and Methods: A two-component GIC system (Fuji IX) andcommercially available antibiotic tablets including ciprofloxacin and amoxicillin /clavulanate were used. The two typesof powdered antibiotics were incorporated and stirred with the GIC powder at a ratio of 2 wt%. A total number of 120Specimens were prepared using a split Teflon mold and grouped as follows; group I: Conventional GIC as a controlgroup, group II: Ciprofloxacin-modified GIC, group III: (Amoxicillin/Clavulanate)-modified GIC, group IV: acombination of the two antibiotics-modified GIC. Each …

Invitro Evaluation Of Bioceramic Sealer Penetration In Radicular Dentin: A Confocal Microscopy Study, Mai A. Wahab, Mohammad O. Shawky, Amany E. Badr

Mansoura Journal of Dentistry

Objective: To assess the area of sealer penetration into dentinal tubules in different sections ofthe root canal using a confocal laser scanning microscope after irrigation with NaOCl and followed by ultrasonicactivation. Materials and Methods: Mandibular premolars were selected according to the inclusion criteria which are:single straight root canal or slightly curved, fully developed apex with patent foramina, no obstruction in the canalsystem or indication of internal and/or external resorption or signs of crack or fracture, then the teeth were prepared,irrigated using NaOCl, activated, and then filled with Meta Biomed CeraSeal Bioceramic sealer using a single coneobturation technique. Rhodamine B was …