Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Rehabilitation and Therapy (5)
- Physical Therapy (4)
- Medical Specialties (3)
- Medical Sciences (2)
- Analytical, Diagnostic and Therapeutic Techniques and Equipment (1)
-
- Bioethics and Medical Ethics (1)
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1)
- Diseases (1)
- Medical Genetics (1)
- Medical Neurobiology (1)
- Neurology (1)
- Nursing (1)
- Orthopedics (1)
- Other Analytical, Diagnostic and Therapeutic Techniques and Equipment (1)
- Pediatrics (1)
- Sports Sciences (1)
- Surgery (1)
- Institution
- Keyword
-
- Female (2)
- Humans (2)
- Male (2)
- Thomas Jefferson University (2)
- 80 and over (1)
-
- Acetates (1)
- Acetazolamide (1)
- Adolescent (1)
- Adult (1)
- Aged (1)
- Aged, 80 and over (1)
- Amidohydrolases (1)
- Animals (1)
- Aspartic Acid (1)
- Biomechanics (1)
- Brain (1)
- Brain Edema (1)
- Calcium Compounds (1)
- Canavan Disease (1)
- Cervical Vertebrae (1)
- Child (1)
- Cholesterol (1)
- Combined Modality Therapy (1)
- Cystic Fibrosis (1)
- Cytomegalovirus (1)
- DNA (1)
- Department of Neurosurgery (1)
- Dependovirus (1)
- Disease Progression (1)
- Exocrine glands (1)
- Publication
- Publication Type
Articles 1 - 11 of 11
Full-Text Articles in Medicine and Health Sciences
Global Cns Gene Transfer For A Childhood Neurogenetic Enzyme Deficiency: Canavan Disease., Paola Leone, Christopher G Janson, Scott J Mcphee, Matthew J During
Global Cns Gene Transfer For A Childhood Neurogenetic Enzyme Deficiency: Canavan Disease., Paola Leone, Christopher G Janson, Scott J Mcphee, Matthew J During
Department of Neurosurgery Faculty Papers
The neurogenetic prototypic disease on which we chose to test our gene therapy strategy is Canavan disease (CD). CD is an autosomal recessive leukodystrophy associated with spongiform degeneration of the brain. At present the disease is uniformly fatal in affected probands. CD is characterized by mutations in the aspartoacylase (ASPA) gene, resulting in loss of enzyme activity. In this review, recent evidence is summarized on the etiology and possible treatments for CD. In particular, we discuss two gene delivery systems representing recent advances in both viral and liposome technology: a novel cationic liposome-polymer-DNA (LPD) complex, DCChol/DOPE-protamine, as well as recombinant …
Dysphagia In Hereditary Sensory Autonomic Neuropathy Type Iv, U Shah, M Arshad, T Mozaffar
Dysphagia In Hereditary Sensory Autonomic Neuropathy Type Iv, U Shah, M Arshad, T Mozaffar
Department of Paediatrics and Child Health
No abstract provided.
The Effects Of Therapeutic Ultrasound On Open Wounds, Martha Henao Bloyer
The Effects Of Therapeutic Ultrasound On Open Wounds, Martha Henao Bloyer
FIU Electronic Theses and Dissertations
The purpose of this study was to evaluate the evidence for the effectiveness of therapeutic ultrasound (US) therapy in the treatment of open wounds as an adjunct to the usual and customary treatment provided by physical therapists. An exhaustive search of all published studies on the effects of therapeutic ultrasound on open wounds was performed. Every article, which met certain criteria, was reviewed in detail. Criteria included the use of human subjects, animal subjects, or human cells in vitro, publication in referred journals indexed by MEDLINE, CINAHL and availability of full text in the English language. Fourteen studies met the …
Radiculopathy And Myelopathy At Segments Adjacent To The Site Of A Previous Anterior Cervical Arthrodesis., Alan S. Hilibrand, Gregory D. Carlson, M A Palumbo, P K Jones, H H Bohlman
Radiculopathy And Myelopathy At Segments Adjacent To The Site Of A Previous Anterior Cervical Arthrodesis., Alan S. Hilibrand, Gregory D. Carlson, M A Palumbo, P K Jones, H H Bohlman
Rothman Institute Faculty Papers
BACKGROUND: We studied the incidence, prevalence, and radiographic progression of symptomatic adjacent-segment disease, which we defined as the development of new radiculopathy or myelopathy referable to a motion segment adjacent to the site of a previous anterior arthrodesis of the cervical spine.
METHODS: A consecutive series of 374 patients who had a total of 409 anterior cervical arthrodeses for the treatment of cervical spondylosis with radiculopathy or myelopathy, or both, were followed for a maximum of twenty-one years after the operation. The annual incidence of symptomatic adjacent-segment disease was defined as the percentage of patients who had been disease-free at …
A Two-Year Prospective Study Of Infant Postural Torticollis, Baii-Jia Yang, Hwei-Chu Lin
A Two-Year Prospective Study Of Infant Postural Torticollis, Baii-Jia Yang, Hwei-Chu Lin
Rehabilitation Practice and Science
Torticollis is a common physical finding in infants, and congenital muscular torticollis is the most commonly reported type. If the only findings are head tilting and facial asymmetry without limitation of ROM of the neck and lack of pathological change of the sternocleidomastoid muscle, infant postural torticollis is the most likely diagnosis. From June, 1995 to May, 1997 we prospectively studied 211 cases of postural and muscular torticollis and excluded other causes of head tilting. The male to female ratio was 114:97, and left to right side ratio 104:107. 130 cases (61.6%) had infant postural torticollis (Group I), while 81 …
An Examination Of Patient And Nurse Perceptions Of Stressors During The Electrophysiology Study, Donna J. Thurn
An Examination Of Patient And Nurse Perceptions Of Stressors During The Electrophysiology Study, Donna J. Thurn
Masters Theses
The purpose of this study was to (a) identify the perceived stressors of patients undergoing an electrophysiology study (EPS) and (b) compare them to the stressors identified by nurses caring for those patients.
A descriptive two group comparative design with a non-probability convenience sample was used. Data were obtained using self report questionnaires. The sample consisted of 25 patients undergoing an EPS and 25 nurse responses. Data analyses included a comparison of the ordering of stressors according to perceived concern by the patient and the nurse. While similar items were identified, there was a difference in the perceived order of …
A Comparison Of The Maximal Torque Production Of The Quadriceps Muscle During Morning And Afternoon Strength Assessment, Shawn Mccoul
A Comparison Of The Maximal Torque Production Of The Quadriceps Muscle During Morning And Afternoon Strength Assessment, Shawn Mccoul
Physical Therapy Scholarly Projects
The purpose of this study was to compare maximal quadriceps torque production in early morning hours to afternoon hours. Thirty male subjects volunteered to participate in this study and were randomly assigned to an AM or PM testing session. At least one week after the first test, the subjects completed a similar test in the opposite time slot. Each subject was positioned on the Kin-Com (Chattecx Corp., Chattanooga, 'IN) dynamometer and performed six maximal concentric isokinetic repetitions of knee extension at 600/s between the ROM of 10° and 80° of knee flexion. The AM/PM ratios indicated no significant difference between …
Research Based Practice Among Members Of The Michigan Physical Therapy Association, Sarah M. Bennett, James D. Courter, Rachel E. Hastings
Research Based Practice Among Members Of The Michigan Physical Therapy Association, Sarah M. Bennett, James D. Courter, Rachel E. Hastings
Masters Theses
The purpose of this study was to investigate the extent to which research based practice (RBP) is employed by Michigan Physical Therapy Association Members by assessing attitudes toward research, level of research involvement/scholarly pursuit, and reasons for using or not using treatment interventions.
Three hundred and thirty questionnaires were distributed by mail to a random sample of Michigan Physical Therapy Association Members. A total of 133 questionnaires were used for analysis. Descriptive frequencies were calculated for each section of the questionnaire. Chi-square and Fischer's Exact tests were used to examine significant relationships.
Respondents in the present study overwhelmingly supported (~90%) …
Xvii International Symposium On Biomechanics In Sports, June 30-July 6, 1999, Edith Cowan University, Perth, Western Australia: Fundamental Skills, Ross Sanders (Ed.)
Xvii International Symposium On Biomechanics In Sports, June 30-July 6, 1999, Edith Cowan University, Perth, Western Australia: Fundamental Skills, Ross Sanders (Ed.)
Research outputs pre 2011
No abstract provided.
The Conservative Treatment Of Patellofemoral Pain Syndrome, Claude W. Massee
The Conservative Treatment Of Patellofemoral Pain Syndrome, Claude W. Massee
Physical Therapy Scholarly Projects
It is estimated that up to 5% of outpatients to physical therapy will present with patellofemoral pain syndrome. This disease is rarely disabling but may significantly and negatively affect the adolescent's and young adult's participation in sporting and recreational activities. Appropriate management is essential to improve quality of life and prevent future musculoskeletal problems.
Historically, here has been some confusion in defining patellofemoral pain syndrome and in determining the exact cause of this troublesome disease. These factors may make the diagnosis and treatment of patellofemoral pain syndrome frustrating to the patient and clinician.
This study, using a review of the …
Cystic Fibrosis: Biological And Ethical Considerations, Sarah Elizabeth Milam
Cystic Fibrosis: Biological And Ethical Considerations, Sarah Elizabeth Milam
Honors Theses
Cystic fibrosis (CF) is a progressive, multisystem disease whose etiology is a genetic mutation in the CF gene product, cystic fibrosis transmembrane conductance regulator (CFTR). The disorder affects all exocrine glands, with common symptoms involving the lungs and pancreas. Although the CF gene and its protein product have been identified, two aspects of the disease make CF particularly difficult to diagnose and manage: (a) variability in both degree and pattern of the mutation in different individuals and (b) lack of information regarding the precise molecular and cellular mechanisms responsible. Let us begin by examining the pathogenesis and pathophysiology of the …