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Predictive Value Of The Hemizona Assay For Pregnancy Outcome In Patients Undergoing Controlled Ovarian Hyperstimulation With Intrauterine Insemination., Murat Arslan, Mahmood Morshedi, Ebru Arslan, Steve Taylor, Arzu Kanik, E. Duran, Sergio Oehninger
Predictive Value Of The Hemizona Assay For Pregnancy Outcome In Patients Undergoing Controlled Ovarian Hyperstimulation With Intrauterine Insemination., Murat Arslan, Mahmood Morshedi, Ebru Arslan, Steve Taylor, Arzu Kanik, E. Duran, Sergio Oehninger
Eyup Hakan Duran
OBJECTIVE: The hemizona assay (HZA) is an established functional test that examines in vitro sperm-zona pellucida binding capacity with high predictive power for fertilization outcome in IVF. The objective of this study was to evaluate the value of the HZA as a predictor of pregnancy in patients undergoing controlled ovarian hyperstimulation (COH) and intrauterine insemination (IUI). DESIGN: Prospective clinical study. SETTING: Academic center. PATIENT(S): Eighty-two couples with unexplained or male factor infertility that underwent 313 IUI cycles. INTERVENTION(S): Basic semen analysis and HZA were performed within three months of starting COH/IUI therapy. MAIN OUTCOME MEASURE(S): Hemizona index (HZI) and clinical …