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Association Of Body Mass Index Genetic Risk Markers With Body Composition During Adolescence, Brice A. Smoker
Association Of Body Mass Index Genetic Risk Markers With Body Composition During Adolescence, Brice A. Smoker
Senior Theses
Background. Obesity affects nearly a fifth of all children in the United States and is a common risk factor for numerous chronic diseases. Many risk factors contribute to obesity, including race and genetics. Obesity is partially heritable, and many genetic loci have been identified as being associated with body mass index (BMI) in adults. Some of these loci have also been associated with childhood BMI, with effects strengthening with age. A previous genome-wide association study (GWAS) identified five single nucleotide polymorphisms (SNPs) associated with changes in BMI in children aged 1 – 17 years.
Purpose. The purpose of the current …