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Ginseng Extract Treatment Influences On Preimplantation Development In Vitro, And Pregnancy And Post-Partum Development In The Mouse, Danyka D. Belanger

Electronic Thesis and Dissertation Repository

Ginseng is one of the most commonly consumed herbal medicines in the world. Consumption is highest in females, thus my purpose was to define the concentration responsive effects of North American alcoholic and aqueous ginseng extracts on preimplantation development in vitro and on pregnancy and post-partum development in the mouse. 2-cell embryos from female mice were cultured with 5 different concentrations of both extracts, ginsenosides Rb1, Rg1 and Re, a combinatorial ginsenoside solution and a polysaccharide fraction. Embryonic development and recovery from treatment was assessed. To investigate in vivo effects of ginseng extracts, females were gavaged with 50 mg/kg and …