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Full-Text Articles in Medicine and Health Sciences

Prenatal Cocaine Exposure Alters Alpha2 Receptor Expression In Adolescent Rats, Rosemarie M. Booze, David R. Wallace, Janelle M. Silvers, Barbara J. Strupp, Diane M. Snow, Charles F. Mactutus Apr 2006

Prenatal Cocaine Exposure Alters Alpha2 Receptor Expression In Adolescent Rats, Rosemarie M. Booze, David R. Wallace, Janelle M. Silvers, Barbara J. Strupp, Diane M. Snow, Charles F. Mactutus

Neuroscience Faculty Publications

BACKGROUND: Prenatal cocaine exposure produces attentional deficits which to persist through early childhood. Given the role of norepinephrine (NE) in attentional processes, we examined the forebrain NE systems from prenatal cocaine exposed rats. Cocaine was administered during pregnancy via the clinically relevant intravenous route of administration. Specifically, we measured alpha2-adrenergic receptor (alpha2-AR) density in adolescent (35-days-old) rats, using [3H]RX821002 (5 nM).

RESULTS: Sex-specific alterations of alpha2-AR were found in the hippocampus and amygdala of the cocaine-exposed animals, as well as an upregulation of alpha2-AR in parietal cortex.

CONCLUSION: These data suggest that prenatal cocaine exposure results in a persistent alteration …


The Effect Of A Low Glycemic Index Diet During Pregnancy On Obstetric Outcomes, Robert G. Moses, M J. Luebcke, Warren S. Davis, K J. Coleman, Linda C. Tapsell, Peter Petocz, Jennie C. Brand-Miller Jan 2006

The Effect Of A Low Glycemic Index Diet During Pregnancy On Obstetric Outcomes, Robert G. Moses, M J. Luebcke, Warren S. Davis, K J. Coleman, Linda C. Tapsell, Peter Petocz, Jennie C. Brand-Miller

Faculty of Health and Behavioural Sciences - Papers (Archive)

Abstract presented at The 2006 Annual Scientific Meeting of the Nutrition Society of Australia, 29 November - 2 December, Sydney, Australia


Investigation Of Serum Cu, Zn, Fe And Se Concentrations During Pregnancy (60, 100 And 150 Days) And After Parturition (45 Days) In Single And Twin Pregnant Sheep, Fuat Gürdoğan, Ati̇lla Yildiz, Engi̇n Balikçi Jan 2006

Investigation Of Serum Cu, Zn, Fe And Se Concentrations During Pregnancy (60, 100 And 150 Days) And After Parturition (45 Days) In Single And Twin Pregnant Sheep, Fuat Gürdoğan, Ati̇lla Yildiz, Engi̇n Balikçi

Turkish Journal of Veterinary & Animal Sciences

This study was conducted to determine the serum Cu, Zn, Se and Fe concentrations at 60, 100, and 150 days of pregnancy and at 45 days of parturition in twin and single pregnant sheep. A total of 30 pregnant Akkaraman sheep in 2 groups (15 single pregnancies, 15 twin pregnancies), aged 3-5 years and weighing 40-50 kg were used. The blood samples were analyzed for serum Cu, Zn, Se and Fe concentrations. No statistically significant difference was found for Se, Cu, Fe and Zn concentrations between the twin and single pregnancy groups. Insignificant decreases (P > 0.05) in serum Zn and …