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Patterns Of Regional Cerebral Blood Flow As A Function Of Obesity In Adults., Daniel G Amen, Joseph Wu, Noble George, Andrew Newberg
Patterns Of Regional Cerebral Blood Flow As A Function Of Obesity In Adults., Daniel G Amen, Joseph Wu, Noble George, Andrew Newberg
Marcus Institute of Integrative Health Faculty Papers
BACKGROUND: While obesity has been shown to be a risk factor for Alzheimer's disease, the potential mechanisms underlying this risk may be clarified with better understanding of underlying physiology in obese persons.
OBJECTIVE: To identify patterns of cerebral perfusion abnormality in adults as a function of body mass index (BMI) defined weight categories, including overweight or obese status.
METHODS: A large psychiatric cohort of 35,442 brain scans across 17,721 adults (mean age 40.8±16.2 years, range 18-94 years) were imaged with SPECT during baseline and concentration scans, the latter done after each participant completed the Connors Continuous Performance Test II. ANOVA …