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Full-Text Articles in Medicine and Health Sciences
Letter: Pneumoperitoneum Secondary To Cunnilingus., S. Ashai, D. Lipton, A. Colon, Jennifer Niebyl
Letter: Pneumoperitoneum Secondary To Cunnilingus., S. Ashai, D. Lipton, A. Colon, Jennifer Niebyl
Jennifer R Niebyl
No abstract provided.
Ultrasonic Aspiration Transducer For Management Of Rh Incompatibility., J. Rampone, R. Sanders, Jennifer Niebyl
Ultrasonic Aspiration Transducer For Management Of Rh Incompatibility., J. Rampone, R. Sanders, Jennifer Niebyl
Jennifer R Niebyl
No abstract provided.
Clinical Evaluation Of Two Direct Procedures For Free Thyroxin, And Of Free Thyroxin Index Determined Nonisotopically And By Measuring Thyroxin-Binding Globulin., J. Waud, D. Chan, H. Drew, M. Oropeza, M Sucupira, B. Scheinin, G. Garrison, M Mayo, E. Taylor, J. Stem, Jennifer Niebyl
Clinical Evaluation Of Two Direct Procedures For Free Thyroxin, And Of Free Thyroxin Index Determined Nonisotopically And By Measuring Thyroxin-Binding Globulin., J. Waud, D. Chan, H. Drew, M. Oropeza, M Sucupira, B. Scheinin, G. Garrison, M Mayo, E. Taylor, J. Stem, Jennifer Niebyl
Jennifer R Niebyl
We have investigated the clinical utility of two direct radioimmunoassays for free thyroxin, an enzyme-inhibition immunoassay, and a direct measurement of thyroxin-binding globulin (TBG) by radioassay. All assay methods correctly identified greater than or equal to 90% of euthyroid, hyperthyroid, and hypothyroid patients who had normal TBG concentrations. In patients with altered TBG concentrations, none of the assays correctly classified all categories of patients. However, the direct assays of free thyroxin concentrations were able to classify correctly more patients with altered TBG concentrations than did the free thyroxin index methods. The free thyroxin index methods evaluated may be acceptable for …
Treatment Of Premature Labor With Indomethacin., D. Blake, Jennifer Niebyl, R. White, K. Kumor, N. Dubin, J. Robinson, P. Egner
Treatment Of Premature Labor With Indomethacin., D. Blake, Jennifer Niebyl, R. White, K. Kumor, N. Dubin, J. Robinson, P. Egner
Jennifer R Niebyl
No abstract provided.
Gonococcal Salpingitis In Pregnancy, R. R. Genadry, B. H. Thompson, Jennifer Niebyl
Gonococcal Salpingitis In Pregnancy, R. R. Genadry, B. H. Thompson, Jennifer Niebyl
Jennifer R Niebyl
No abstract provided.
Experience With An Adolescent Pregnancy Program. A Preliminary Report, D. Youngs, Jennifer Niebyl, D. Blake, D. Shipp, J. Stanley, T. King
Experience With An Adolescent Pregnancy Program. A Preliminary Report, D. Youngs, Jennifer Niebyl, D. Blake, D. Shipp, J. Stanley, T. King
Jennifer R Niebyl
A program has been designed to give comprehensive health care services to pregnant adolescents. The program components include community liason, patient education, counseling and social services, a nurse "on call" program for labor and delivery, and pediatric nurse-practitioner followup. In addition, a drug use identification component screens the patients by interview and urinalysis. Hypertensive disorders of pregnancy occurred in 10% of the first 202 patients. Forty-three percent had anemia (hematocrit less than 35%), and screening cervical cultures for gonorrhea were positive in 3.5%. Cigarettes, alcohol, and marijuana constituted the most common nonmedical drugs used, and aspirin the most common medical …
The Effect Of Magnesium Sulfate On Fetal Heart Rate Baseline Variability, A. Babaknia, Jennifer Niebyl
The Effect Of Magnesium Sulfate On Fetal Heart Rate Baseline Variability, A. Babaknia, Jennifer Niebyl
Jennifer R Niebyl
Variability of the baseline fetal heart rate is correlated with good fetal outcome, and loss of baseline variability has been observed as a sign of fetal distress. Central nervous system depressing drugs may also decrease fetal heart rate variability, and thus recognition of the effect of medication on the baseline fetal heart rate is important for accurate interpretation of fetal monitor tracings. In the cases reported, marked decrease in fetal heart rate variability was observed within 4 minutes of intravenous administration of magnesium sulfate, and fetal outcome was good in all cases.
Folic Acid And Prevention Of Birth Defects, D. Van Dyke, P. Stumbo, J. Mary, Jennifer Niebyl
Folic Acid And Prevention Of Birth Defects, D. Van Dyke, P. Stumbo, J. Mary, Jennifer Niebyl
Jennifer R Niebyl
No abstract provided.
Efficacy Of Screening For Gestational Diabetes, G. Marquette, V. Klein, Jennifer Niebyl
Efficacy Of Screening For Gestational Diabetes, G. Marquette, V. Klein, Jennifer Niebyl
Jennifer R Niebyl
A cost analysis of glucose screening was studied prospectively in 434 patients. All patients underwent a 50-gm oral glucose load followed by a 1-hour plasma glucose screen test at 28 weeks (+/- 2 weeks). Patients with a screen test greater than or equal to 130 mg/dl plasma glucose were further tested with an oral glucose tolerance test. Also, previously described clinical risk factors for diabetes were documented on all patients. A 3.3% prevalence of gestational diabetes was found in 178 patients with risk factors, compared with 2.4% of 256 patients without risk factors, not a significant difference. Ten of the …
Prevention Of Perinatal Transmission Of Hepatitis B Virus: The Sensitivity, Specificity, And Predictive Value Of The Recommended Screening Questions To Detect High-Risk Women In An Obstetric Population, G. Mcquillan, T. Townsend, C. Johannes, T. Dillard, R. Molteni, P. Ness, Jennifer Niebyl
Prevention Of Perinatal Transmission Of Hepatitis B Virus: The Sensitivity, Specificity, And Predictive Value Of The Recommended Screening Questions To Detect High-Risk Women In An Obstetric Population, G. Mcquillan, T. Townsend, C. Johannes, T. Dillard, R. Molteni, P. Ness, Jennifer Niebyl
Jennifer R Niebyl
The Advisory Committee on Immunization Practices recommends that all pregnant women be questioned concerning risk factors for hepatitis B virus infection and that those giving positive responses be serotested. The sensitivity, specificity, and predictive value of those recommended questions among 692 parturient women were determined. A total of 59 currently or previously infected women (hepatitis B surface antigen (HBsAg), antibody to hepatitis B surface antigen (anti-HBs), or antibody to hepatitis B core antigen (anti-HBc) seropositive) were compared with the 633 seronegative women. Among nonwhite women, the sensitivity of a positive response to any one of the recommended questions was 60%. …
Neonatal Outcome After Indomethacin Treatment For Preterm Labor, Jennifer Niebyl, F. Witter
Neonatal Outcome After Indomethacin Treatment For Preterm Labor, Jennifer Niebyl, F. Witter
Jennifer R Niebyl
Forty-six infants exposed to indomethacin in utero for treatment for preterm labor were compared with infants from two control groups. In one control group the next consecutive patient treated with a tocolytic agent was used, and the other control group was formed by picking the next consecutive patient matched by gestational age who did not receive any tocolytic agent. There was no significant difference in Apgar scores, birth weight, or gestational age in the three groups. The incidence of neonatal complications including hypocalcemia, hypoglycemia, respiratory distress syndrome, patient ductus arteriosus, sepsis, and neonatal mortality were not significantly different in the …
A Placebo-Controlled Randomized Trial Of The Terbutaline Pump For Prevention Of Preterm Delivery, K. Wenstrom, C. Weiner, D. Merrill, Jennifer Niebyl
A Placebo-Controlled Randomized Trial Of The Terbutaline Pump For Prevention Of Preterm Delivery, K. Wenstrom, C. Weiner, D. Merrill, Jennifer Niebyl
Jennifer R Niebyl
To determine the efficacy of the terbutaline pump for the prevention of preterm delivery, patients in preterm labor defined by progressive cervical change underwent intravenous magnesium sulfate tocolysis (with or without oral indomethacin, as necessary), and once labor was arrested, were randomized to one of three treatment arms: terbutaline by pump, saline by pump (blinded), or oral terbutaline. If recurrent preterm labor occurred despite maximization of therapy, the treatment arm was determined and therapy was changed; saline pump and oral terbutaline were switched to terbutaline pump, terbutaline pump was switched to oral terbutaline. Patients who continued to labor were readmitted …
Penile Nerve Block For Newborn Circumcision, L. Maxwell, M. Yaster, R. Wetzel, Jennifer Niebyl
Penile Nerve Block For Newborn Circumcision, L. Maxwell, M. Yaster, R. Wetzel, Jennifer Niebyl
Jennifer R Niebyl
Circumcision in neonates is performed, almost universally, without anesthesia or analgesia. It is associated with pain, crying, agitation, and physiologic stress. Twenty infants receiving penile nerve block for circumcision were compared with ten infants having circumcision without anesthesia. Heart rate and blood pressure rose 34 and 15%, respectively, in unblocked infants, and were unchanged in infants receiving local anesthesia. Oxygen saturation declined 16% in unanesthetized infants compared with 6% in blocked infants (P less than .03). Anesthetized infants were less agitated and cried less. Peak plasma concentrations of the local anesthetic lidocaine averaged 0.51 +/- 0.17 microgram/mL (range 0.1-1.6), well …
The Validity Of The Leukocyte Esterase Reagent Test Strip In Detecting Significant Leukocyturia, G. Marquette, T. Dillard, S. Bietla, Jennifer Niebyl
The Validity Of The Leukocyte Esterase Reagent Test Strip In Detecting Significant Leukocyturia, G. Marquette, T. Dillard, S. Bietla, Jennifer Niebyl
Jennifer R Niebyl
This prospective trial demonstrated that the best possible definition for a positive leukocyte esterase test (Chemstrip 9) is + or ++. With use of this definition, the sensitivity in detecting significant leukocyturia is 83% and the specificity is 70%. The use of this test strip could reduce screening costs in registering obstetric patients.
Inhibition Of Arachidonic Acid Metabolism In The Perinatal Period: Pharmacology, Clinical Application, And Potential Adverse Effects, F. Witter, Jennifer Niebyl
Inhibition Of Arachidonic Acid Metabolism In The Perinatal Period: Pharmacology, Clinical Application, And Potential Adverse Effects, F. Witter, Jennifer Niebyl
Jennifer R Niebyl
No abstract provided.
The Bland-White-Garland Syndrome In Pregnancy, V. Klein, J. Repke, G. Marquette, Jennifer Niebyl
The Bland-White-Garland Syndrome In Pregnancy, V. Klein, J. Repke, G. Marquette, Jennifer Niebyl
Jennifer R Niebyl
No abstract provided.
Inhibition Of Preterm Labor, Jennifer Niebyl, J. Johnson
Inhibition Of Preterm Labor, Jennifer Niebyl, J. Johnson
Jennifer R Niebyl
No abstract provided.
The Glycosphingolipid Composition Of The Placenta Of A Blood Group P Fetus Delivered By A Blood Group Pk1 Woman And Analysis Of The Anti-Globoside Antibodies Found In Maternal Serum, G. Hansson, K. Wazniowska, J. Rock, P. Ness, T. Kickler, R. Shirey, Jennifer Niebyl, D. Zopf
The Glycosphingolipid Composition Of The Placenta Of A Blood Group P Fetus Delivered By A Blood Group Pk1 Woman And Analysis Of The Anti-Globoside Antibodies Found In Maternal Serum, G. Hansson, K. Wazniowska, J. Rock, P. Ness, T. Kickler, R. Shirey, Jennifer Niebyl, D. Zopf
Jennifer R Niebyl
To further define the molecules that may mediate spontaneous abortion due to maternal-fetal blood group incompatibility within the P blood group system, we have examined the fine specificities of maternal antibodies and the glycolipid antigens from the placenta of a P infant born to a Pk1 mother. Maternal antibodies obtained during therapeutic plasmapheresis were analyzed to determine their reactivities with placental glycolipid extracts on thin-layer plates. Second antibodies specific for IgM, IgG, and IgA revealed immunoglobulins of all of these classes strongly reactive with one major placental glycolipid that comigrates with globoside. GC/MS analysis confirmed that the major P-active pentaglycosylceramide …
Use Of Antibiotics For Ear, Nose, And Throat Disorders In Pregnancy And Lactation, Jennifer Niebyl
Use Of Antibiotics For Ear, Nose, And Throat Disorders In Pregnancy And Lactation, Jennifer Niebyl
Jennifer R Niebyl
No abstract provided.
Folate, Carotene, And Smoking, F. Witter, D. Blake, R. Baumgardner, E. Mellits, Jennifer Niebyl
Folate, Carotene, And Smoking, F. Witter, D. Blake, R. Baumgardner, E. Mellits, Jennifer Niebyl
Jennifer R Niebyl
No abstract provided.
Metastatic Adenocarcinoma Of The Lung Complicating Pregnancy. A Case Report, R. Suda, J. Repke, R. Steer, Jennifer Niebyl
Metastatic Adenocarcinoma Of The Lung Complicating Pregnancy. A Case Report, R. Suda, J. Repke, R. Steer, Jennifer Niebyl
Jennifer R Niebyl
A case of large cell undifferentiated adenocarcinoma of the lung was complicated by an aggressive clinical course and documented placental metastases. The management of these neoplasms is complex, requiring one to pay attention to the maternal, as well as fetal and neonatal, prognosis.
Folate, Zinc, And Vitamin B-12 Intake During Pregnancy And Postpartum, M. Berg, D. Van Dyke, C. Chenard, Jennifer Niebyl, S. Hirankarn, A. Bendich, P. Stumbo
Folate, Zinc, And Vitamin B-12 Intake During Pregnancy And Postpartum, M. Berg, D. Van Dyke, C. Chenard, Jennifer Niebyl, S. Hirankarn, A. Bendich, P. Stumbo
Jennifer R Niebyl
No abstract provided.
Fetal Distress During A Maternal Systemic Allergic Reaction, V. Klein, A. Harris, R. Abraham, Jennifer Niebyl
Fetal Distress During A Maternal Systemic Allergic Reaction, V. Klein, A. Harris, R. Abraham, Jennifer Niebyl
Jennifer R Niebyl
Systemic allergic reactions to food ingestion rarely result in life-threatening situations. When these reactions occur during pregnancy, however, the accompanying physiologic changes may result in fetal distress. A case of repetitive late decelerations in the fetal heart rate during a maternal allergic reaction is presented. Prompt and aggressive medical management brought about total resolution of maternal and fetal compromise.
The Inhibition Of Premature Labor With Indomethacin, Jennifer Niebyl, D. Blake, R. White, K. Kumor, N. Dubin, J. Robinson, P. Egner
The Inhibition Of Premature Labor With Indomethacin, Jennifer Niebyl, D. Blake, R. White, K. Kumor, N. Dubin, J. Robinson, P. Egner
Jennifer R Niebyl
We administered indomethacin orally for the treatment of premature labor in a prospective, randomized, double-blind fashion, and all infants were followed up. Indomethacin was significantly more effective than placebo in inhibition of premature labor during a 24-hour course of therapy, with treatment failure during therapy occurring in only one of 15 indomethacin-treated patients compared to nine of 15 placebo-treated patients (p less than 0.01). Mean plasma concentrations of indomethacin were approximately 0.8 micrograms/ml at both 4 and 12 hours after administration. Mean plasma levels of 15-oxo-13,14-dihydroprostaglandin F2 alpha (PGFM) were similar in the two groups before treatment, decreased markedly in …
Drugs And Related Areas In Pregnancy, Jennifer Niebyl
Drugs And Related Areas In Pregnancy, Jennifer Niebyl
Jennifer R Niebyl
No abstract provided.
The Influence Of Aspirin On The Course Of Induced Midtrimester Abortion, Jennifer Niebyl, D. Blake, L. Burnett, T. King
The Influence Of Aspirin On The Course Of Induced Midtrimester Abortion, Jennifer Niebyl, D. Blake, L. Burnett, T. King
Jennifer R Niebyl
Prostaglandins appear to mediate the uterine contractions of abortion and labor, and aspirin has been shown to be an inhibitor of prostaglandin synthesis. In this double-blind, placebo-controlled, prospective, and randomized study, aspirin was administered orally in doses of 600 mg. every 6 hours to patients undergoing induced midtrimester abortions with hyperosmolar urea and oxytocin augmentation. The mean injection-abortion interval was significantly prolonged by aspirin in nulliparous patients (aspirin 32.3 +/- 3.3 hr. vs. placebo 21.5 +/- 3.5 hr.) and no aspirin-treated nullipara aborted in less than 18 hours. There was no significant difference between treatment groups in the mean injection-abortion …
Cost-Effective Criteria For Glucose Screening, G. Marquette, V. Klein, J. Repke, Jennifer Niebyl
Cost-Effective Criteria For Glucose Screening, G. Marquette, V. Klein, J. Repke, Jennifer Niebyl
Jennifer R Niebyl
To study cost-effective screening criteria for gestational diabetes, a prospective study of 1012 patients was completed. All patients underwent a glucose screen between 26 and 30 weeks of gestation, consisting of a 50-g oral glucose load followed by a one-hour plasma glucose determination. Patients with a glucose screen greater than or equal to 130 mg/dL were studied with a standard three-hour oral glucose tolerance test. The incidence of gestational diabetes was 2.4% (24 of 1012). Only one gestational diabetic was identified with a glucose screen below 150 mg/dL. Twenty-two of the 24 cases were at least 24 years old. Twenty-one …
Letter: Pneumoperitoneum Secondary To Cunnilingus, S. Ashai, D. Lipton, A. Colon, Jennifer Niebyl
Letter: Pneumoperitoneum Secondary To Cunnilingus, S. Ashai, D. Lipton, A. Colon, Jennifer Niebyl
Jennifer R Niebyl
No abstract provided.
Methotrexate And Misoprostol To Terminate Early Pregnancy, J. Yankowitz, Jennifer Niebyl
Methotrexate And Misoprostol To Terminate Early Pregnancy, J. Yankowitz, Jennifer Niebyl
Jennifer R Niebyl
No abstract provided.
Pharmacogenetic Screening For Susceptibility To Fetal Malformations In Women, D. Van Dyke, V. Ellingrod, M. Berg, Jennifer Niebyl, A. Sherbondy, D. Trembath
Pharmacogenetic Screening For Susceptibility To Fetal Malformations In Women, D. Van Dyke, V. Ellingrod, M. Berg, Jennifer Niebyl, A. Sherbondy, D. Trembath
Jennifer R Niebyl
OBJECTIVE: To present a review of the literature and research on the pharmacogenetics of congenital defects, with a focus on the need for predictive maternal genotype assays. DATA SOURCE: MEDLINE searches (January 1985-January 1999), past reference reviews, and unpublished research. STUDY SELECTION: Review of relevant human, animal, and basic science studies. DATA EXTRACTION: Data on research on polymorphisms, genotyping, cytochrome P450 enzyme systems, epoxide hydrolase, folate metabolism, metabolism of anticonvulsant medications, molecular genetics of neural tube defects, variations in drug metabolism, and environmental exposures were evaluated. DATA SYNTHESIS: Data synthesis includes not only a review of the literature but suggests …