Medicine and Health Sciences Commons^™

Firearm-Related Traumatic Brain Injuries In Adults: A Scoping Review., Gabriel Reyes, Ron Gadot, Lara Ouellette, Shervin H Nouri, Shankar P Gopinath, Akash J Patel

Library Staff Publications

BACKGROUND AND OBJECTIVES: Firearm-related traumatic brain injury (TBI) has emerged as a significant public health issue in the United States, coinciding with a rapid increase in gun-related deaths. This scoping review aims to update our understanding of firearm-related TBI in adult populations.

METHODS: A comprehensive search of 6 online databases yielded 22 studies that met the inclusion criteria. The reviewed studies predominantly focused on young adult men who were victims of assault, although other vulnerable populations were also affected.

RESULTS: Key factors in evaluating patients with firearm-related TBI included low Glasgow Coma Scale scores, central nervous system involvement, hypotension, and …

Validated Assessment Tools For Screen Media Use: A Systematic Review., Oriana Perez, Tatyana Garza, Olivia Hindera, Alicia Beltran, Salma M Musaad, Tracey Dibbs, Anu Singh, Shria Chug, Amy Sisson, Anil Kumar Vadathya, Tom Baranowski, Teresia M O'Connor

Library Staff Publications

OBJECTIVE: Accurate measurement of adult and child screen media use are needed to robustly assess its impact on health outcomes. Our objective was to systematically review screen media use measurement tools that have been validated against an objective "gold standard" tool.

METHODS: The search strategy was initially conducted in Medline Ovid and translated to Embase, Web of Science, PsychInfo and Cochrane. A modified natural language search was conducted in Google Scholar and IEEE. The initial search was conducted in March 2021, and an updated search was conducted in June 2022. Additional studies were included from the references. Studies had to …

Management Of Mammalian Bites To The External Genitalia: A Scoping Review., Sagar R Patel, Pratik Kanabur, Harlee E Possoit, Austin Kinley, Beatriz Varman, Michael Coburn, Shyam Sukumar

Library Staff Publications

OBJECTIVE: To review existing publications to determine the approaches for the medical and operative management of mammalian bites to the external genitalia.

MATERIALS AND METHODS: The Preferred Reporting Items for Systematic Reviews and Meta-Analysis for Scoping Review guidelines were followed. Four databases were searched. Articles were independently screened and analysed by two reviewers. Publications were included if detailed summaries of genitalia bites and management were documented. Discrepancies were resolved by a third reviewer. Data were extracted from the final article cohort.

RESULTS: A total of 42 articles were included in this scoping review with 67 cases of mammalian bites to …

Outcomes Of Exercise Interventions In Patients With Advanced Liver Disease: A Systematic Review Of Randomized Clinical Trials., Taher Jamali, Taaj Raasikh, Gabriel Bustamante, Amy Sisson, Puneeta Tandon, Andres Duarte-Rojo, Ruben Hernaez

Library Staff Publications

INTRODUCTION: Frailty and sarcopenia are common complications of advanced liver disease. Owing to associated morbidity/mortality, there have been targeted efforts to prevent and/or improve both by enrolling these patients in focused exercise programs. This review systematically analyzes the data of randomized clinical trials (RCTs) on anthropometric, physical fitness, quality-of-life, and safety outcomes of exercise interventions in patients with advanced liver disease.

METHODS: Two authors independently searched trials on PubMed and EMBASE from inception up to November 18, 2021. A third independent arbitrator adjudicated all disagreements. We qualitatively summarized these outcomes as follows: (i) muscular fitness (maximal inspiratory/expiratory pressures, muscle size, …

Quality Assessment Of Optic Nerve Sheath Diameter Ultrasonography: Scoping Literature Review And Delphi Protocol., Mohammad I Hirzallah, Piergiorgio Lochner, Muhammad Ubaid Hafeez, Andrew G Lee, Christos Krogias, Deepa Dongarwar, Ramneek Manchanda, Lara Ouellette, Nicholas D Hartman, Michael Ertl, Felix Schlachetzki, Chiara Robba

Library Staff Publications

BACKGROUND AND PURPOSE: The optic nerve is surrounded by the extension of meningeal coverings of the brain. When the pressure in the cerebrospinal fluid increases, it causes a distention of the optic nerve sheath diameter (ONSD), which allows the use of this measurement by ultrasonography (US) as a noninvasive surrogate of elevated intracranial pressure. However, ONSD measurements in the literature have exhibited significant heterogeneity, suggesting a need for consensus on ONSD image acquisition and measurement. We aim to establish a consensus for an ONSD US Quality Criteria Checklist (ONSD US QCC).

METHODS: A scoping systematic review of published ultrasound ONSD …

Firearm-Related Pediatric Head Trauma: A Scoping Review., Ron Gadot, Melissa A Lopresti, David N Smith, Lara Ouellette, Sandi Lam

Library Staff Publications

BACKGROUND: Firearm-related injury is a significant cause of morbidity and mortality in pediatric populations. Despite a disproportionate role in the most morbid outcomes in both traumatic brain injury and firearm-related injury populations, firearm-related traumatic brain injury (frTBI) is an understudied epidemiological entity. There is need to increase understanding and promote interventions that reduce this burden of disease.

OBJECTIVE: To assess the evidence characterizing pediatric frTBI to highlight trends and gaps regarding burden of disease and interventions to reduce frTBI.

METHODS: We conducted a scoping review under Preferred Reporting Items for Systematic Reviews and Meta-Analyses-Scoping Review (PRISMA-ScR) guidelines on peer-reviewed studies …

Incidence And Risk Factors Of Transplantation-Associated Thrombotic Microangiopathy: A Systematic Review And Meta-Analysis., Victoria Van Benschoten, Cayla Roy, Rohit Gupta, Lara Ouellette, Sangeeta Hingorani, Ang Li

Library Staff Publications

Transplantation-associated thrombotic microangiopathy (TA-TMA) is an increasingly recognized post-transplantation complication, yet the overall incidence of the disease remains under debate. To determine the pooled incidence of TA-TMA in a systematic review of literature and to identify consistent risk factors. We performed a systematic review using the MEDLINE, Embase, and CENTRAL databases to identify cohort studies that reported incidence of and risk factors for TA-TMA from 2004 to 2020. We conducted a meta-analysis of proportion to estimate the pooled incidence of TA-TMA using a random-effects model. We assessed moderators of heterogeneity through subgroup analysis, risk of bias through ROBINS-I, and publication …

Promoting Nutrition Equity For Individuals With Physical Challenges: A Systematic Review Of Barriers And Facilitators To Healthy Eating., Marianna S Wetherill, Ashten R Duncan, Hartley Bowman, Reagan Collins, Natalie Santa-Pinter, Morgan Jackson, Catherine M Lynn, Katherine Prentice, Mary Isaacson

Library Staff Publications

Impaired mobility is the most common form of functional disability in the US, affecting one out of every sixteen working-age adults. Little is known about the barriers to and facilitators of healthy eating among people with impaired mobility (PWIM), who are at increased risk for diet-related chronic disease. The pathways by which impaired mobility influence dietary intake are unclear, yet likely involve a complex interplay between structural determinants of health and individual factors. To help advance nutrition equity initiatives for PWIM, this systematic review aimed to qualitatively synthesize factors associated with dietary intake across four levels of ecologic influence. An …

Positional Installation Of Intranasal Corticosteroids In The Treatment Of Chronic Rhinosinusitis: A Systematic Review Of The Literature., Emily L Cummings, Scott N Fassas, Kevin J Sykes, Amy Sisson, Alexander G Chiu, Meha G Fox

Library Staff Publications

OBJECTIVES: First-line treatment of chronic rhinosinusitis includes topical corticosteroids aimed at decreasing inflammation of sinonasal mucosa. No guidelines exist regarding the effect of head position during administration of corticosteroids. We hypothesize certain positions enhance delivery to the paranasal sinuses, with further improvement in delivery after sinus surgery.

METHODS: A systematic review of the literature was conducted using Medline Ovid, Embase, Scopus, and Cochrane databases. All studies evaluating intranasal medications administered in 2 or more head positions were included. Study population, head position(s), method/volume of delivery, and outcome metrics were recorded.

RESULTS: Twenty-four studies compared head positions and their role in …

Mortality In Hospitalized Patients With Cancer And Coronavirus Disease 2019: A Systematic Review And Meta-Analysis Of Cohort Studies., Aakash Desai, Rohit Gupta, Shailesh Advani, Lara Ouellette, Nicole M Kuderer, Gary H Lyman, Ang Li

Library Staff Publications

BACKGROUND: Heterogeneous evidence exists on the effect of coronavirus disease 2019 (COVID-19) on the clinical outcomes of patients with cancer.

METHODS: A systematic review was performed using the Medline, Embase, and CENTRAL databases and the World Health Organization Novel Coronavirus website to identify studies that reported mortality and characteristics of patients with cancer who were diagnosed with COVID-19. The primary study outcome was mortality, defined as all-cause mortality or in-hospital mortality within 30 days of initial COVID-19 diagnosis. The pooled proportion of mortality was estimated using a random-effects model, and study-level moderators of heterogeneity were assessed through subgroup analysis and …

Women Have A Lower Risk Of Nonalcoholic Fatty Liver Disease But A Higher Risk Of Progression Vs Men: A Systematic Review And Meta-Analysis., Maya Balakrishnan, Parth Patel, Sydney Dunn-Valadez, Cecilia Dao, Vinshi Khan, Hiba Ali, Laith El-Serag, Ruben Hernaez, Amy Sisson, Aaron P Thrift, Yan Liu, Hashem B El-Serag, Fasiha Kanwal

Library Staff Publications

BACKGROUND & AIMS: The risk of nonalcoholic fatty liver disease (NAFLD) and its progression may differ between men and women. We conducted a systematic review and meta-analysis to determine the relationship between sex and NAFLD, nonalcoholic steatohepatitis (NASH), and advanced NAFLD fibrosis.

METHODS: Studies reporting sex-stratified NAFLD prevalence among population-based samples and either NASH or advanced fibrosis among patients with biopsy-proven NAFLD were identified from MEDLINE, EMBASE, and Cochrane databases through December 2017. We calculated pooled relative risk ratios comparing women vs men for each outcome.

RESULTS: Our final analysis comprised 54 studies. Samples sizes were 62,239 for the NAFLD …

Maternal Hookworm Infection And Its Effects On Maternal Health: A Systematic Review And Meta-Analysis., Tara E Ness, Vedika Agrawal, Kathryn Bedard, Lara Ouellette, Timothy A Erickson, Peter Hotez, Jill E Weatherhead

Library Staff Publications

Hookworm is an intestinal parasite that infects nearly 230 million people, with another 5.1 billion at risk, especially in poverty-stricken tropical and subtropical regions. Pregnancy is an especially vulnerable time for hookworm infection because of its effect on both maternal and subsequently fetal health. A systematic review and meta-analysis was conducted. The meta-analysis was performed on the association between maternal hookworm and maternal anemia, as well as maternal hookworm coinfection with malaria. The prevalence of hookworm ranged from 1% to 78% in pregnant women, whereas malaria prevalence ranged from 11% to 81%. Pregnant women with hookworm infection were more likely …

Maternal Hookworm Infection And Its Effects On Maternal Health: A Systematic Review And Meta-Analysis., Tara E Ness, Vedika Agrawal, Kathryn Bedard, Lara Ouellette, Timothy A Erickson, Peter Hotez, Jill E Weatherhead

Library Staff Publications

Hookworm is an intestinal parasite that infects nearly 230 million people, with another 5.1 billion at risk, especially in poverty-stricken tropical and subtropical regions. Pregnancy is an especially vulnerable time for hookworm infection because of its effect on both maternal and subsequently fetal health. A systematic review and meta-analysis was conducted. The meta-analysis was performed on the association between maternal hookworm and maternal anemia, as well as maternal hookworm coinfection with malaria. The prevalence of hookworm ranged from 1% to 78% in pregnant women, whereas malaria prevalence ranged from 11% to 81%. Pregnant women with hookworm infection were more likely …

Developing Interagency Collaboration To Address The Opioid Epidemic: A Scoping Review Of Joint Criminal Justice And Healthcare Initiatives., Andrea J Yatsco, Tiffany Champagne-Langabeer, Travis F Holder, Angela L Stotts, James R Langabeer

Library Staff Publications

BACKGROUND: With the current opioid epidemic impacting well over half of all counties across the United States, initiatives that encourage interagency collaboration between first responder organizations appear necessary to comprehensively address this crisis. Police, fire, and emergency medical services (EMS) are in a unique position to identify substance users and provide necessary resources to initiate treatment, yet there is not sufficient evidence of joint collaborative programs between law enforcement/first responders and healthcare providers.

METHODS: In this scoping review we examine the current state of joint criminal justice and healthcare interventions, specifically, opioid and substance use pre-arrest initiatives via emergency first …

Systematic Review With Meta-Analysis: Prevalence Of Prior And Concurrent Barrett's Oesophagus In Oesophageal Adenocarcinoma Patients., Mimi C Tan, Nabil Mansour, Donna L White, Amy Sisson, Hashem B El-Serag, Aaron P Thrift

Library Staff Publications

BACKGROUND: The proportions of patients with oesophageal adenocarcinoma (OAC) diagnosed by Barrett's oesophagus surveillance or with pre-existing Barrett's oesophagus are unclear.

AIM: To estimate the prevalence of prior and concurrent Barrett's oesophagus diagnosis among patients with OAC or oesophagogastric junction adenocarcinomas (OGJAC).

METHODS: We searched PubMed and Embase to identify studies published 1966-1/8/2020 that examined the prevalence of prior (≥6 months) or concurrent Barrett's diagnosis (at cancer diagnosis) among OAC and OGJAC patients. Random effects models estimated overall and stratified pooled prevalence rates.

RESULTS: A total of 69 studies, including 33 002 OAC patients (53 studies) and 2712 patients with …

The Relationship Between Chronic Health Conditions And Cognitive Deficits In Children, Adolescents, And Young Adults With Down Syndrome: A Systematic Review., Kellen C Gandy, Heidi A Castillo, Lara Ouellette, Jonathan Castillo, Philip J Lupo, Lisa M Jacola, Karen R Rabin, Kimberly P Raghubar, Maria M Gramatges

Library Staff Publications

BACKGROUND: Individuals with Down syndrome are predisposed to a number of chronic health conditions, but the relationship between these conditions and cognitive ability is not clear. The primary objective of this systematic review is to assess this relationship by evaluating studies that measure cognitive performance in the context of Down syndrome-associated chronic health conditions.

METHODS: A systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines. Studies included in this review (1) included children, adolescent, and young adult participants with Down syndrome and one or more co-occurring health conditions; (2) were quantitative; …

Antithrombin Population Pharmacokinetics In Pediatric Ventricular Assist Device Patients., Brady S Moffett, Marc Anders, Timothy Humlicek, Marianne Galati, Jun Teruya, Iki Adachi, Sebastian Tume

Library Staff Publications

OBJECTIVES: Describe the pharmacokinetics of antithrombin in pediatric patients undergoing ventricular assist device therapy and provide dosing recommendations for antithrombin in this population.

DESIGN: A retrospective population pharmacokinetic study was designed.

SETTING: Large tertiary care children's hospital Subject inclusion criteria consisted of less than 19 years old.

PATIENTS: Subjects less than 19 years old undergoing therapy with a HeartWare ventricular assist device (HeartWare, Framingham, MA) or Berlin EXCOR ventricular assist device (Berlin GmbH, Berlin, Germany), who received a dose of antithrombin with a postdose antithrombin activity level from January 1, 2011, to June 30, 2017.

INTERVENTIONS: Population pharmacokinetic analysis and …

Screening For Undiagnosed Bleeding Disorders In Post-Tonsillectomy Bleed Patients: Retrospective Review And Systematic Review Of The Literature., Sarah A Gitomer, Grace Shebha Anand, Hallie E Bradley, Manish Kumar, Lara Ouellette, Mary F Musso

Library Staff Publications

OBJECTIVES: There is currently no standard for screening children with post-tonsillectomy bleeds (PTB) for coagulopathy disorders. This study aims to identify children with occult coagulopathy diagnosed at PTB and to identify factors associated with diagnosis. A systematic review of the literature further identified trends in this topic.

METHODS: A retrospective chart review of patients returning to the operating room for PTB at a tertiary children's hospital was undertaken from 2012 to 2016. A systematic review using Medline OVID was subsequently performed.

RESULTS: Of 12,503 tonsillectomies, 311 children (52% male, mean age 8 years) required surgery for PTB (2.5% rate). Twenty-one …

Handoffs From The Operating Room To The Intensive Care Unit After Cardiothoracic Surgery: From The Society Of Thoracic Surgeons Workforce On Critical Care., Subhasis Chatterjee, Jay G Shake, Rakesh C Arora, Daniel T Engelman, Michael S Firstenberg, Charles M Geller, Hitoshi Hirose, Vassyl A Lonchyna, Francis T Lytle, Rita K C Milewski, Rainer G H Moosdorf, Joseph Rabin, Rohan Sanjanwala, Marianne Galati, Glenn J Whitman

Library Staff Publications

No abstract provided.

Clinical Application Of Genome And Exome Sequencing As A Diagnostic Tool For Pediatric Patients: A Scoping Review Of The Literature., Hadley Stevens Smith, J Michael Swint, Seema R Lalani, Jose-Miguel Yamal, Marcia C De Oliveira Otto, Stephan Castellanos, Amy Taylor, Brendan H Lee, Heidi V Russell

Library Staff Publications

PURPOSE: Availability of clinical genomic sequencing (CGS) has generated questions about the value of genome and exome sequencing as a diagnostic tool. Analysis of reported CGS application can inform uptake and direct further research. This scoping literature review aims to synthesize evidence on the clinical and economic impact of CGS.

METHODS: PubMed, Embase, and Cochrane were searched for peer-reviewed articles published between 2009 and 2017 on diagnostic CGS for infant and pediatric patients. Articles were classified according to sample size and whether economic evaluation was a primary research objective. Data on patient characteristics, clinical setting, and outcomes were extracted and …

Meta-Analysis Of The Incidence And Patterns Of Second Neoplasms After Photon Craniospinal Irradiation In Children With Medulloblastoma., Abhishek Bavle, Sayani Tewari, Amy Sisson, Murali Chintagumpala, Michael Anderson, Arnold C Paulino

Library Staff Publications

BACKGROUND: Second neoplasms (SNs) are a well-established long-term adverse effect of radiation therapy (RT), but there are limited data regarding their incidence and location relative to the radiation field, specific to medulloblastoma (MB) survivors after craniospinal irradiation (CSI).

METHODS: A systematic literature review, per Preferred Reporting Items for Systematic Reviews and Meta-Analyses, identified six studies reporting the incidence and locations of SNs for 1,114 patients with MB, after CSI, with a median follow-up of ∼9 years (7.6-15.4 years). The study-specific cumulative incidence (CI) of SNs, second benign neoplasms (SBNs), and second malignant neoplasms (SMNs) were standardized to a 10-year time …

Consumer Health Information For Asians (Chia): A Collaborative Project., Deborah D. Halsted, Beatriz Varman, Marsha Sullivan, Lynne Nguyen

Library Staff Publications

According to the 2000 United States Census, the Asian population in Houston, Texas, has increased more than 67% in the last ten years. To supplement an already active consumer health information program, the staff of the Houston Academy of Medicine-Texas Medical Center Library worked with community partners to bring health information to predominantly Asian neighborhoods. Brochures on health topics of concern to the Asian community were translated and placed in eight informational kiosks in Asian centers such as temples and an Asian grocery store. A press conference and a ribbon cutting ceremony were held to debut the kiosks and to …