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Fatigue

Wayne State University

Medical Student Research Symposium

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Sleep And Function In Patients With Multiple Sclerosis, Nawar Aljundi, Kelsey Arvai, Michael Mitchell, Jennifer Martin, Abdulghani Sankari, M. Safwan Badr Jan 2021

Sleep And Function In Patients With Multiple Sclerosis, Nawar Aljundi, Kelsey Arvai, Michael Mitchell, Jennifer Martin, Abdulghani Sankari, M. Safwan Badr

Medical Student Research Symposium

Introduction: Fatigue is a core symptom of Multiple Sclerosis (MS) and impairs function and quality of life in this patient population. Studies show that sleep-disordered breathing is also common in persons with MS and may exacerbate fatigue symptoms. Within a larger study of patients with spinal cord injuries and disorders, we evaluated the relationships among sleep-disordered breathing (SDB) severity, sleep quality, and functional outcomes in patients with MS. Our objective was to examine the impact of SDB severity on the severity of fatigue and functional impairment in this population.

Methods: Twenty-five subjects (average age=57(11), min=35, max=79; 80% male; average …