Medicine and Health Sciences Commons^™

A Comparison Study; Sexuality In Women With Insulin-Dependent Diabetes Mellitus And In Women Without Chronic Illness, Beth Eubank

MSN Research Projects

The relationship between chronic illness and sexuality has long been recognized, and diabetes mellitus is a chronic illness affecting 16 million individuals in the United States. The purpose of this descriptive comparative study was to explore sexuality in the insulin-dependent diabetic female. The research hypothesis that guided the study was there is no difference in perceived sexuality for women with insulin-dependent diabetes and women without chronic illness. The sample consisted of 30 females between the ages of 21 and 40 years who had not experienced surgical menopause and were clients in primary care clinics in the Mississippi Delta. Fifteen of …

Neuronal Toxicity Of Humoral Factors From Patients With Diabetic Neuropathy And Mechanism Of Neuronal Death On Cultured Adrenergic Neurons: Studies Of Autoimmune Pathogenesis In Diabetic Neuropathy, Dong Liu

Theses and Dissertations in Biomedical Sciences

Diabetic neuropathy is an extremely common medical problem because of the high frequency of diabetes and its complications. Diabetic neuropathy consists of not one, but many patterns of nerve injury, each potentially with its own discrete pathogenic mechanisms. Evidence is accumulating that indicates autoimmunity plays a role in diabetic peripheral neuropathy. However, the significance of immunopathogenesis of diabetic neuropathy is as yet unclear.

Using the N1E-115 mouse neuroblastoma cell line (NB) as a model of the adrenergic autonomic neuron, we found that sera of IDDM patients with neuropathy inhibit growth and differentiation of adrenergic neurons in culture (Pittenger et al, …