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Full-Text Articles in Medicine and Health Sciences

Loperamide-Induced Cardiac Events: Case Reports And Review., Vivek Modi, Matthew Krinock, Ravi V. Desai Md, Steven Stevens, Sudip Nanda Dec 2021

Loperamide-Induced Cardiac Events: Case Reports And Review., Vivek Modi, Matthew Krinock, Ravi V. Desai Md, Steven Stevens, Sudip Nanda

Cardiology Division

Reports of cardiac arrhythmia secondary to loperamide toxicity have become increasingly common in the literature. We present two patients in their mid-20s, each having overdosed on loperamide and subsequently manifesting life-threatening cardiac arrhythmias not otherwise explained by known pathology. An analysis of the limited research available indicates that loperamide's capacity to block ion channels may be responsible for these events. A better mechanistic understanding of loperamide's effects can help inform clinical management of patients with these life-threatening symptoms as at this time no set guidelines for management have yet been established.


Gender Analysis Of Publishing Among Medical Students In Dermatology, Michelle Militello, Mindy D. Szeto, Kayd J. Pulsipher, Abigail L. Meckley, Kristen H. Ward, Taylor Harp, Colby L. Presley, Cara Barber, Hope R. Rietcheck, Taylor M. Runion, Chandler W. Rundle, Robert P. Dellavalle Dec 2021

Gender Analysis Of Publishing Among Medical Students In Dermatology, Michelle Militello, Mindy D. Szeto, Kayd J. Pulsipher, Abigail L. Meckley, Kristen H. Ward, Taylor Harp, Colby L. Presley, Cara Barber, Hope R. Rietcheck, Taylor M. Runion, Chandler W. Rundle, Robert P. Dellavalle

Research and Historical Works - 2021

No abstract provided.


The Many Faces Of Covid19 Infection: A Case Of Multisystem Inflammatory Syndrome In Adults (Mis-A), Amy Lam Do, Kaitlyn Musco Md, Nicholas Hinds Md Oct 2021

The Many Faces Of Covid19 Infection: A Case Of Multisystem Inflammatory Syndrome In Adults (Mis-A), Amy Lam Do, Kaitlyn Musco Md, Nicholas Hinds Md

Posters

No abstract provided.


Severe Iron Deficiency Anemia Causing Pericardial Effusion, Emily C. Skutnik Do, Anita Fei Md, Alisha Hossain Do, Desire G. Guthier Do, Andrew Viscusi Do, Bradley Lash Md, Ali Yazdanyar Do Oct 2021

Severe Iron Deficiency Anemia Causing Pericardial Effusion, Emily C. Skutnik Do, Anita Fei Md, Alisha Hossain Do, Desire G. Guthier Do, Andrew Viscusi Do, Bradley Lash Md, Ali Yazdanyar Do

Posters

No abstract provided.


Management And Outcomes Of Cardiogenic Shock In Cardiac Icus With Versus Without Shock Teams., Alexander I Papolos, Benjamin B Kenigsberg, David D Berg, Carlos L Alviar, Erin Bohula, James A Burke Md, Anthony P Carnicelli, Sunit-Preet Chaudhry, Stavros Drakos, Daniel A Gerber, Jianping Guo, James M Horowitz, Jason N Katz, Ellen C Keeley, Thomas S Metkus, Jose Nativi-Nicolau, Jeffrey R Snell, Shashank S Sinha, Wayne J Tymchak, Sean Van Diepen, David A Morrow, Christopher F Barnett Sep 2021

Management And Outcomes Of Cardiogenic Shock In Cardiac Icus With Versus Without Shock Teams., Alexander I Papolos, Benjamin B Kenigsberg, David D Berg, Carlos L Alviar, Erin Bohula, James A Burke Md, Anthony P Carnicelli, Sunit-Preet Chaudhry, Stavros Drakos, Daniel A Gerber, Jianping Guo, James M Horowitz, Jason N Katz, Ellen C Keeley, Thomas S Metkus, Jose Nativi-Nicolau, Jeffrey R Snell, Shashank S Sinha, Wayne J Tymchak, Sean Van Diepen, David A Morrow, Christopher F Barnett

Cardiology Division

BACKGROUND: Single-center studies suggest that implementation of multidisciplinary cardiogenic shock (CS) teams is associated with improved CS survival.

OBJECTIVES: The aim was to characterize practice patterns and outcomes in the management of CS across multiple centers with versus without shock teams.

METHODS: The Critical Care Cardiology Trials Network is a multicenter network of cardiac intensive care units (CICUs) in North America. All consecutive medical admissions to each CICU (n = 24) were captured during annual 2-month collection periods (2017-2019; n = 6,872). Shock management and CICU mortality among centers with versus without shock teams were compared using inverse probability weighting. …


Assessing The Clinical Characteristics And Ventilator Parameters Of Covid-19 Mechanically Ventilated Patients At Lehigh Valley Health Network, Andrew Kelly, Kenneth Miller Med, Rrt-Nps Aug 2021

Assessing The Clinical Characteristics And Ventilator Parameters Of Covid-19 Mechanically Ventilated Patients At Lehigh Valley Health Network, Andrew Kelly, Kenneth Miller Med, Rrt-Nps

Research Scholars

No abstract provided.


Esr And Crp Testing May Not Be Useful In Monitoring Patients With Native Vertebral Osteomyelitis, Abigail Heilenman, Amy Slenker Md Aug 2021

Esr And Crp Testing May Not Be Useful In Monitoring Patients With Native Vertebral Osteomyelitis, Abigail Heilenman, Amy Slenker Md

Research Scholars

No abstract provided.


People Living With Hiv (Plwh) And Covid-19. The Lvhn Experience, Jacob Frank, Marcelo Gareca Md Aug 2021

People Living With Hiv (Plwh) And Covid-19. The Lvhn Experience, Jacob Frank, Marcelo Gareca Md

Research Scholars

No abstract provided.


The Effect Of Patient Age In Progression To A Hemorrhoidectomy, Justin Yoon, William Sangster Aug 2021

The Effect Of Patient Age In Progression To A Hemorrhoidectomy, Justin Yoon, William Sangster

Research Scholars

No abstract provided.


Closing Gaps In The Care Of Patients With Heart-Kidney Disease: The Time Is Now., Janani Rangaswami Jun 2021

Closing Gaps In The Care Of Patients With Heart-Kidney Disease: The Time Is Now., Janani Rangaswami

Department of Medicine Faculty Papers

No abstract present.


Durability Of Left Bundle Branch Area Pacing – Long-Term Follow Up On A New Technique, Nikhil A. Mehta Md, Syed Rafay A. Sabzwari Md, Bilal Saqi Md, Rahul Gupta Md, Apurva Vyas Md, Jeffrey Gordon Md, Talha Nazir Md, Sergio Cossu Md, Ronald S. Freudenberger Md, Babak Bozorgnia Md May 2021

Durability Of Left Bundle Branch Area Pacing – Long-Term Follow Up On A New Technique, Nikhil A. Mehta Md, Syed Rafay A. Sabzwari Md, Bilal Saqi Md, Rahul Gupta Md, Apurva Vyas Md, Jeffrey Gordon Md, Talha Nazir Md, Sergio Cossu Md, Ronald S. Freudenberger Md, Babak Bozorgnia Md

Department of Medicine

No abstract provided.


What’S In The Lv? A Story Of Scad Leading To Anterior Apical Aneurysm With Left Ventricular Thrombus, Lekha Racharla Do, Zeel Patel Do, Tyler Boozel Do, Rahul Gupta Md, Sagar Vadhar Do, Akhil Kher Md, Ellina C. Feiner Md, Yasotha Rajeswaran Md, Daniel J. Makowski Do May 2021

What’S In The Lv? A Story Of Scad Leading To Anterior Apical Aneurysm With Left Ventricular Thrombus, Lekha Racharla Do, Zeel Patel Do, Tyler Boozel Do, Rahul Gupta Md, Sagar Vadhar Do, Akhil Kher Md, Ellina C. Feiner Md, Yasotha Rajeswaran Md, Daniel J. Makowski Do

Department of Medicine

No abstract provided.


Development Of A Gme Wellness Program At One Sponsoring Institution: One Year’S Journey, Despina Tsarouhis Bs, Margaret A. Hadinger Edd, Joseph E. Patruno Md, Carmine Pellosie Do, Mph, Mba, Daniel Relles Md, Kevin M. Correll Mdiv, Mapc, Richard Drabic Lcsw, Johnathon Dallarosa Md, Lekha Racharla Do May 2021

Development Of A Gme Wellness Program At One Sponsoring Institution: One Year’S Journey, Despina Tsarouhis Bs, Margaret A. Hadinger Edd, Joseph E. Patruno Md, Carmine Pellosie Do, Mph, Mba, Daniel Relles Md, Kevin M. Correll Mdiv, Mapc, Richard Drabic Lcsw, Johnathon Dallarosa Md, Lekha Racharla Do

Department of Education

No abstract provided.


Infective Endocarditis-Associated Glomerulonephritis Versus Cryoglobulinemic Glomerulonephritis: An Unfortunate Clinical Overlap, Yesha K. Shah Do, Emilee E. Kurtz Do, Sharon E. Maynard Md, Mohammad Saqib Md May 2021

Infective Endocarditis-Associated Glomerulonephritis Versus Cryoglobulinemic Glomerulonephritis: An Unfortunate Clinical Overlap, Yesha K. Shah Do, Emilee E. Kurtz Do, Sharon E. Maynard Md, Mohammad Saqib Md

Department of Medicine

No abstract provided.


Potassium For Two: Management Of Refractory Electrolyte Disturbances In Gitelman Syndrome During Pregnancy, Eric Torkildsen Md, Yesha K. Shah Do, Sharon E. Maynard Md May 2021

Potassium For Two: Management Of Refractory Electrolyte Disturbances In Gitelman Syndrome During Pregnancy, Eric Torkildsen Md, Yesha K. Shah Do, Sharon E. Maynard Md

Department of Medicine

No abstract provided.


Rising Above The Challenge: Using An Enhanced Staffing Model To Improve Care For Covid-19 Patients, Anne Rabert Mhsa, Rn, Ccrn, Ne-Bc, Sandra Derbyshire Rn, Ccrn, Pamela Sellars Bsn, Rn, Ccrn Apr 2021

Rising Above The Challenge: Using An Enhanced Staffing Model To Improve Care For Covid-19 Patients, Anne Rabert Mhsa, Rn, Ccrn, Ne-Bc, Sandra Derbyshire Rn, Ccrn, Pamela Sellars Bsn, Rn, Ccrn

Posters

No abstract provided.


The Undetected Myopathy: Anti-Pl-12 Antisynthetase Syndrome, Alaynna C. Kears Do, Kaitlyn Musco Md, Dylan Soller Do, Arjan Ahluwalia Md Apr 2021

The Undetected Myopathy: Anti-Pl-12 Antisynthetase Syndrome, Alaynna C. Kears Do, Kaitlyn Musco Md, Dylan Soller Do, Arjan Ahluwalia Md

Department of Medicine

No abstract provided.


Presence And Implications Of Sarcopenia In Non-Alcoholic Steatohepatitis., Gregory Habig, Christa Smaltz, Dina Halegoua-De Marzio Apr 2021

Presence And Implications Of Sarcopenia In Non-Alcoholic Steatohepatitis., Gregory Habig, Christa Smaltz, Dina Halegoua-De Marzio

Department of Medicine Faculty Papers

Sarcopenia, defined as the loss of muscle strength, mass, and functionality, confers a poor prognosis in the setting of cirrhosis. Given its clinical significance, a better understanding of the underlying mechanisms leading to cirrhosis, sarcopenia, and their co-occurrence may improve these patients' outcomes. Non-alcoholic steatohepatitis (NASH) shares many of the same etiologies as sarcopenia, including insulin resistance, chronic inflammation, and ectopic adipocyte deposition, which are hallmarks of metabolic syndrome (MS). NASH thus serves as a prime candidate for further exploration into the underlying pathophysiology and relationship between these three conditions. In this review, we discuss the natural history of NASH …


Analysis Of Falls Efficacy Scale And Vulnerable Elders Survey As Predictors Of Falls., Marna R. Greenberg Do, Mph, Facep, Jeanne L. Jacoby Md, Robert D. Barraco Md, Mph, Ali Yazdanyar Do, Phd, Mmm, Ryan M Surmaitis Do, Alexander Youngdahl Do, Richard Chow Do, Sofia Murillo, Allen Zeng, Bryan G. Kane Md Apr 2021

Analysis Of Falls Efficacy Scale And Vulnerable Elders Survey As Predictors Of Falls., Marna R. Greenberg Do, Mph, Facep, Jeanne L. Jacoby Md, Robert D. Barraco Md, Mph, Ali Yazdanyar Do, Phd, Mmm, Ryan M Surmaitis Do, Alexander Youngdahl Do, Richard Chow Do, Sofia Murillo, Allen Zeng, Bryan G. Kane Md

Department of Emergency Medicine

Introduction Falls are the leading cause of injury-related death among older adults according to the Centers for Disease Control and Prevention (CDC). The Falls Efficacy Scale (FES) and Vulnerable Elder Survey (VES-13) are validated screening tools used to assess concern of falling, health deterioration and functional decline. We set out to determine if the FES or VES-13 could serve as a predictor of falls among older adults in the Emergency Department (ED) setting. Methods This prospective pilot cohort study was conducted at a Level 1 Trauma Center. ED patients aged ≥65 were eligible for the study if they had a …


Myocardial T1 And T2 Mapping By Magnetic Resonance In Patients With Immune Checkpoint Inhibitor-Associated Myocarditis., Paaladinesh Thavendiranathan, Lili Zhang, Amna Zafar, Zsofia D Drobni, Syed S Mahmood, Marcella Cabral, Magid Awadalla, Anju Nohria, Daniel A Zlotoff, Franck Thuny, Lucie M Heinzerling, Ana Barac, Ryan J Sullivan, Carol L Chen, Dipti Gupta, Michael C Kirchberger, Sarah E Hartmann, Jonathan W Weinsaft, Hannah K Gilman, Muhammad A. Rizvi Md, Bojan Kovacina, Caroline Michel, Gagan Sahni, Ana González-Mansilla, Antonio Calles, Francisco Fernández-Avilés, Michael Mahmoudi, Kerry L Reynolds, Sarju Ganatra, Juan José Gavira, Nahikari Salterain González, Manuel García De Yébenes Castro, Raymond Y Kwong, Michael Jerosch-Herold, Otavio R Coelho-Filho, Jonathan Afilalo, Eduardo Zataraín-Nicolás, A John Baksi, Bernd J Wintersperger, Oscar Calvillo-Arguelles, Stephane Ederhy, Eric H Yang, Alexander R Lyon, Michael G Fradley, Tomas G Neilan Mar 2021

Myocardial T1 And T2 Mapping By Magnetic Resonance In Patients With Immune Checkpoint Inhibitor-Associated Myocarditis., Paaladinesh Thavendiranathan, Lili Zhang, Amna Zafar, Zsofia D Drobni, Syed S Mahmood, Marcella Cabral, Magid Awadalla, Anju Nohria, Daniel A Zlotoff, Franck Thuny, Lucie M Heinzerling, Ana Barac, Ryan J Sullivan, Carol L Chen, Dipti Gupta, Michael C Kirchberger, Sarah E Hartmann, Jonathan W Weinsaft, Hannah K Gilman, Muhammad A. Rizvi Md, Bojan Kovacina, Caroline Michel, Gagan Sahni, Ana González-Mansilla, Antonio Calles, Francisco Fernández-Avilés, Michael Mahmoudi, Kerry L Reynolds, Sarju Ganatra, Juan José Gavira, Nahikari Salterain González, Manuel García De Yébenes Castro, Raymond Y Kwong, Michael Jerosch-Herold, Otavio R Coelho-Filho, Jonathan Afilalo, Eduardo Zataraín-Nicolás, A John Baksi, Bernd J Wintersperger, Oscar Calvillo-Arguelles, Stephane Ederhy, Eric H Yang, Alexander R Lyon, Michael G Fradley, Tomas G Neilan

Hematology-Medical Oncology Division

BACKGROUND: Myocarditis is a potentially fatal complication of immune checkpoint inhibitor (ICI) therapy. Data on the utility of cardiovascular magnetic resonance (CMR) T1 and T2 mapping in ICI myocarditis are limited.

OBJECTIVES: This study sought to assess the value of CMR T1 and T2 mapping in patients with ICI myocarditis.

METHODS: In this retrospective study from an international registry of patients with ICI myocarditis, clinical and CMR findings (including T1 and T2 maps) were collected. Abnormal T1 and T2 were defined as 2 SD above site (vendor/field strength specific) reference values and a z-score was calculated for each patient. Major …


A Rare Case Of A Plurihormonal Pituitary Adenoma, Alisha Hossain Do, Lindor Gelin Do, Arjan Ahluwalia Md, Emily C. Skutnik Do, Sonum Singh Md, Gretchen A. Perilli Md, Sharmila C. Koshy Md Mar 2021

A Rare Case Of A Plurihormonal Pituitary Adenoma, Alisha Hossain Do, Lindor Gelin Do, Arjan Ahluwalia Md, Emily C. Skutnik Do, Sonum Singh Md, Gretchen A. Perilli Md, Sharmila C. Koshy Md

Department of Medicine

No abstract provided.


The Difficulty Of Post-Operative Surveillance Of Calcitonin Negative Medullary Thyroid Cancer, Emily C. Skutnik Do, Rachel Kinney Do, Rebecca A. Lopes Do, Chun Siu Do, Angela Magdaleno Do, Gretchen A. Perilli Md Mar 2021

The Difficulty Of Post-Operative Surveillance Of Calcitonin Negative Medullary Thyroid Cancer, Emily C. Skutnik Do, Rachel Kinney Do, Rebecca A. Lopes Do, Chun Siu Do, Angela Magdaleno Do, Gretchen A. Perilli Md

Department of Medicine

No abstract provided.


Brucella Melitensis-Induced Transaminitis., Rajesh Essrani Md, Anastasia Shnitser Md Mar 2021

Brucella Melitensis-Induced Transaminitis., Rajesh Essrani Md, Anastasia Shnitser Md

Department of Medicine

Brucellosis is infrequently reported in the United States and is mostly an occupational hazard among workers engaged in livestock raising and processing. It is a systemic infectious disease and can involve the liver in varying ways, ranging from benign subclinical increases in serum aminotransferase levels to ominous chronic suppurative disease. It is endemic in many countries, primarily those of the Mediterranean region. It is usually treated with antibiotics. We present a case of a 37-year-old female who developed


Development And Validation Of A Prediction Model For Stroke, Cardiac, And Mortality Risk After Non-Cardiac Surgery., Sang H Woo, Gregary D. Marhefka, Scott W. Cowan, Md, Lily Ackermann, Md Feb 2021

Development And Validation Of A Prediction Model For Stroke, Cardiac, And Mortality Risk After Non-Cardiac Surgery., Sang H Woo, Gregary D. Marhefka, Scott W. Cowan, Md, Lily Ackermann, Md

Department of Medicine Faculty Papers

Background: Commonly used cardiovascular risk calculators do not provide risk estimation of stroke, a major postoperative complication with high morbidity and mortality. We developed and validated an accurate cardiovascular risk prediction tool for stroke, major cardiac complications (myocardial infarction or cardiac arrest), and mortality after non-cardiac surgery.

Methods and Results: This retrospective cohort study included 1 165 750 surgical patients over a 4-year period (2007-2010) from the American College of Surgeons National Surgical Quality Improvement Program Database. A predictive model was developed with the following preoperative conditions: age, history of coronary artery disease, history of stroke, emergency surgery, preoperative serum …


Risk Stratification Among Survivors Of Cardiac Arrest Considered For Coronary Angiography., Ahmed A Harhash, Teresa L May, Chiu-Hsieh Hsu, Sachin Agarwal, David B Seder, Michael R Mooney, Nainesh C. Patel Md, John Mcpherson, Paul Mcmullan, Richard Riker, Eldar Soreide, Karen G Hirsch, Pascal Stammet, Alison Dupont, Sten Rubertsson, Hans Friberg, Niklas Nielsen, Tanveer Rab, Karl B Kern Feb 2021

Risk Stratification Among Survivors Of Cardiac Arrest Considered For Coronary Angiography., Ahmed A Harhash, Teresa L May, Chiu-Hsieh Hsu, Sachin Agarwal, David B Seder, Michael R Mooney, Nainesh C. Patel Md, John Mcpherson, Paul Mcmullan, Richard Riker, Eldar Soreide, Karen G Hirsch, Pascal Stammet, Alison Dupont, Sten Rubertsson, Hans Friberg, Niklas Nielsen, Tanveer Rab, Karl B Kern

Cardiology Division

BACKGROUND: The American College of Cardiology Interventional Council published consensus-based recommendations to help identify resuscitated cardiac arrest patients with unfavorable clinical features in whom invasive procedures are unlikely to improve survival.

OBJECTIVES: This study sought to identify how many unfavorable features are required before prognosis is significantly worsened and which features are most impactful in predicting prognosis.

METHODS: Using the INTCAR (International Cardiac Arrest Registry), the impact of each proposed "unfavorable feature" on survival to hospital discharge was individually analyzed. Logistic regression was performed to assess the association of such unfavorable features with poor outcomes.

RESULTS: Seven unfavorable features (of …


Voxelotor Modulates The Analgesic Effect Of Certain Opioids., Samir K. Ballas Feb 2021

Voxelotor Modulates The Analgesic Effect Of Certain Opioids., Samir K. Ballas

Cardeza Foundation for Hematologic Research

No abstract provided.


Ischemic Lumbosacral Plexopathy Following Endoleak Repair Of The Right Iliac Artery, Patrick Davis, Artish Patel, Beth Stepanczuk Md Feb 2021

Ischemic Lumbosacral Plexopathy Following Endoleak Repair Of The Right Iliac Artery, Patrick Davis, Artish Patel, Beth Stepanczuk Md

Department of Medicine

No abstract provided.


A Scoring Tool And Predictive Model To Detect Risk Of Hospitalization From Covid-19, Nicholas Russo Bs, Zhe Chen Md, Matthew M. Miller Do, Robert X. Murphy Jr, Md, Ms, David B. Burmeister Do, Facep, Cpe Feb 2021

A Scoring Tool And Predictive Model To Detect Risk Of Hospitalization From Covid-19, Nicholas Russo Bs, Zhe Chen Md, Matthew M. Miller Do, Robert X. Murphy Jr, Md, Ms, David B. Burmeister Do, Facep, Cpe

Department of Medicine

No abstract provided.


An Outpatient Total Knee Protocol For Optimizing Outcomes And Reducing Variability Of Care, Christopher Johns Pt, Dpt, Ocs, Cert. Mdt, Kimberly Fritts Dpt Feb 2021

An Outpatient Total Knee Protocol For Optimizing Outcomes And Reducing Variability Of Care, Christopher Johns Pt, Dpt, Ocs, Cert. Mdt, Kimberly Fritts Dpt

Department of Medicine

No abstract provided.


Post Stroke Focal Aware Seizures Presenting As Delayed Onset Choreoathetosis, Artish Patel, Patrick Davis, Beth Stepanczuk Md Feb 2021

Post Stroke Focal Aware Seizures Presenting As Delayed Onset Choreoathetosis, Artish Patel, Patrick Davis, Beth Stepanczuk Md

Department of Medicine

No abstract provided.