Medicine and Health Sciences Commons^™

Sex Differences In Stress Reactivity, Brain Morphology, And Oxytocin In The Hypothalamus Of The Gray Short-Tailed Opossum (Monodelphis Domestica), Esperanza I. Zacarias, Daniela Rodriguez, Alexandra Chalons, Sasawan Heingraj, Nicole Altamirano, Joseph Rafac, John L. Vandeberg, Mario Gil

Research Colloquium

Understanding the effects of stress on behavior and cognition is important due to its impact on mental health and wellbeing (Schneiderman et al. 2005). Translational animal research can contribute to the development of new treatments that can improve therapeutic outcomes and our understanding of the neurobiology of stress. In the present study, we complement behavioral stress reactivity with immunohistochemical localization of oxytocin in the hypothalamus, a neuropeptide that regulates stress (Neumann & Slattery, 2016). Oxytocin has potential therapeutic use for mental health disorders (Neumann & Slattery, 2016), and the effects of oxytocin seem to be sexually dimorphic (Love, 2018). Using …

The Effects Of Music Therapy On Elderly Adults With Dementia, Jeante J. Jackson

Dissertations, Theses, and Capstone Projects

As people age, the brain is more susceptible to changes that diminish cognitive function. In recent years neuroscience has found convergent evidence between music therapy and brain architecture, as it has shown the generation of new connections in the brain or a reorganization and possible strengthening of existing connections already in the brain. However, the literature regarding music training’s effects on executive control, selective attention, and speech processing is lacking particularly when it comes to older populations.

This study investigated Verbal Working Memory, Visuospatial Attention and Task Initiation, and Auditory Selective Attention in a 91-year-old adult (B.P.) diagnosed with dementia. …

The Influence Of Early Childhood Parental Feeding Behaviors On Self-Regulation & Food Decision-Making In Young Adults, Natasha Singareddy

CMC Senior Theses

This study used data from a diverse set of undergraduates from the Claremont Colleges to examine the relationship between cognitive control (impulsivity and response inhibition) and self-regulatory ability as an indicator of sustained early childhood parental feeding behaviors in adulthood. In addition, the current study explored if early childhood parental feeding behaviors predicted food decision-making in adulthood as a result of perceived taste and nutritional value of food items. It was hypothesized that heightened impulsivity and impaired response inhibition as measures of cognitive control would correlate to poorer self-regulation, in turn reflecting a particular mode of early childhood parental feeding …

"I Just Want To Be Me, Authentically": Identity Shifting Among Racially And Ethnically Diverse Young Adults, Aerika Brittian Loyd, Dulce Wilkinson Westberg, Lenisha Williams, Marisha Humphries, Alan Meca, Julie Carmen Rodil

Psychology Faculty Publications

Identity shifting represents a common but complex social, behavioral, and cognitive phenomenon. However, some forms of identity shifting originate in response to structural, institutional, and interpersonal marginalization enacted on lower status groups, such as people of color in the United States. The current study investigated ways young adults from diverse ethnic/racial groups discussed shifting to fit in with White Americans (a dominant group) in the United States and their own ethnic/racial group (a minoritized group) and elucidated self-reported motivations for shifting. Participants consisted of 764 young adults (ages = 18–23) recruited from two large public universities in the Southeast and …

The Impact Of Alzheimer Disease On Semantic Knowledge, Maileen G. Ulep

UNLV Theses, Dissertations, Professional Papers, and Capstones

The research furthers the understanding of the impact of Alzheimer disease (AD) on cognition and the organization of semantic knowledge in the brain, which might contribute to the development of diagnostic and staging tools, and interventions to palliate cognitive deficits. The disruption of semantic knowledge in AD is well documented in the literature. Much of the existing research focuses on the general impact AD has on semantic knowledge. This study explores the impact of AD on specific domains of knowledge, chiefly, living kinds and artifacts, critical to ordinary functioning. The content, organization and structure of the investigated domains of knowledge …

The Role Of Leisure Engagement In Fostering Cognition In Aging, Karen Wenzel

All Dissertations

Leisure activities are a major component of healthy aging, associated with reduced risk of cognitive decline and enhanced cognitive function. However, there is wide variation in the conceptualization and measurement of leisure. Specific leisure activities or domains have been studied in association with cognition in aging. More recently, researchers have noted that attributes of the activity, rather than the activity itself, may be significant. This study explored the current state of knowledge regarding attributes of leisure activities that foster cognition in aging. A literature review using PRISMA Scoping Review guidelines identified objectively and subjectively measured attributes of leisure engagement in …

Early Life Exposure To Unpredictable Parental Sensory Signals Shapes Cognitive Development Across Three Species, Elyssia Poggi Davis, Kari Mccormack, Hina Arora, Desiree Sharpe, Annabel K. Short, Jocelyne Bachevalier, Laura M. Glynn, Curt A. Sandman, Hal S. Stern, Mar Sanchez, Tallie Z. Baram

Psychology Faculty Articles and Research

Exposure to early life adversity has long term consequences on cognitive function. Most research has focused on understanding components of early life adversities that contribute to later risk, including poverty, trauma, maltreatment, and neglect. Whereas these factors, in the aggregate, explain a significant proportion of emotional and cognitive problems, there are serious gaps in our ability to identify potential mechanisms by which early life adversities might promote vulnerability or resilience. Here we discuss early life exposure to unpredictable signals from the caretaker as an understudied type of adversity that is amenable to prevention and intervention. We employ a translational approach …

Neuroanatomy In Mild Cognitive Impairment: Relationship To Functional Skills, Treatment Expectancy, And Comorbid Depression, Sara Rushia

Dissertations, Theses, and Capstone Projects

Mild cognitive impairment (MCI) is a neurocognitive disorder defined by cognitive decline in older adults. Although MCI has been studied for decades, there remain important areas to be explored in order to adequately characterize aspects of this disorder that provide information valuable for possible interventions and disease progression to dementia, including a better understanding of the neuroanatomical variables relevant to this disorder. Such neuroanatomical variables include cortical thickness, hippocampal volume, and white matter hyperintensities (WMHs). This dissertation consists of three separate studies aimed at addressing gaps in the literature on MCI in relation to brain morphometrics and under-studied characteristics involved …

The Effects Of Physical Function And Genetics On Cognition And Blood Biomarkers In Individuals At-Risk For Alzheimer’S Disease And Related Dementias, Joshua Louis Gills

Graduate Theses and Dissertations

Alzheimer’s disease and related dementia (ADRD) rates are expected to triple by the year 2050. Early detection and specific mitigation efforts are warranted to blunt the alarming rate. Physical function (PF) declines with age, but higher physical function is associated with better cognitive functioning in middle-to- older age individuals. Moreover, greater physical activity (PA) is associated with better global cognition; however, Apoliporotein e4 carriers may not gain the same benefits with exercise. Additionally, plasma phosphorylated tau 217 (p-tau217) has been identified as a novel diagnostic ADRD biomarker which needs further research to examine associations with risk factors. Therefore, the aims …

Occupational Depression In A Spanish-Speaking Sample: Associations With Cognitive Performance And Work-Life Characteristics, Bianchi Renzo, Guadalupe Manzano García, Maria Pilar Montanes, Emily A. Schonfeld, Irvin Sam Schonfeld

Publications and Research

This 386-participant study investigated the structural and psychometric properties of the Spanish version of the Occupational Depression Inventory (ODI). Exploratory structural equation modeling bifactor analysis revealed that the ODI meets the requirements for essential unidimensionality. Measurement invariance held across our sample and the English- and French-speaking samples used in the ODI’s initial validation study. Mokken scale analysis indicated that (a) the scalability of the instrument was strong, (b) no violations of monotonicity or local independence were present, and (c) invariant item ordering was sufficiently accurate. The ODI’s reliability was optimal. The ODI exhibited both convergent validity and discriminant validity vis-à-vis …

Physical Activity, Academic Performance And Cognition In Children And Adolescents. A Systematic Review, Eero Hapala

Baltic Journal of Health and Physical Activity

A literature review was conducted to investigate the effect of physical exercise and physical training on cognition and academic performance in children and adolescents. Nine randomized or quasi-randomized controlled trials with 2,013 participants were identified by employing the following data sources: the Cochrane Register of Controlled Trials, Medline, Eric, CINAHL, PsychINFO, and ISI Web of Knowledge. Five studies indicated positive effects of physical exercise on attention, concentration, and working memory, and three studies reported positive effects of 14 to 64 week physical training on language and arithmetic skills. Thus, there is some evidence that physical exercise may facilitate cognitive functions …

The Lived Experience Of Individuals Thinking About Food And Coping With Stress, Tobi Martin

Walden Dissertations and Doctoral Studies

Stress results in many people altering their eating patterns, often consuming food high in sugar and fat. Such behavior is a factor in the growing obesity epidemic and can potentially cause the development of chronic diseases, resulting in employment problems and billions of extra dollars spent on national health care programs. Researchers have focused on the concept of “emotional eating” while overlooking the overarching research question of this study, which was about exploring the experience of individuals using eating behavior as a coping mechanism to deal with stress. All responses were viewed through the lens of social cognitive theory. Interviews …

Parent Reports Of Executive Functions In Students With Learning Disability, Jane Roitsch, Annemarie L. Horn, Lisa Morin

Communication Disorders & Special Education Faculty Publications

This study examines the results of the Behavior Rating Inventory of Executive Function (BRIEF-2) (Gioia et al., 2015) reported by parents of children with Specific Learning Disability (LD) and/or other comorbid disabilities. LD is most notably associated with comorbid attention deficit hyperactivity disorder (ADHD) (Alloway & Stein, 2014; Westby &Watson, 2004; Willcutt et al., 2013). A total of 43 parents completed the BRIEF-2 rating scale. Findings suggest children with LD and ADHD display greater challenges with inhibition, working memory, planning, along with greater challenges in organization and metacognition. Parents of children with LD reported their children have greater levels of …

Eye Movement And Pupil Measures: A Review, Bhanuka Mahanama, Yasith Jayawardana, Sundararaman Rengarajan, Gavindya Jayawardena, Leanne Chukoskie, Joseph Snider, Sampath Jayarathna

Computer Science Faculty Publications

Our subjective visual experiences involve complex interaction between our eyes, our brain, and the surrounding world. It gives us the sense of sight, color, stereopsis, distance, pattern recognition, motor coordination, and more. The increasing ubiquity of gaze-aware technology brings with it the ability to track gaze and pupil measures with varying degrees of fidelity. With this in mind, a review that considers the various gaze measures becomes increasingly relevant, especially considering our ability to make sense of these signals given different spatio-temporal sampling capacities. In this paper, we selectively review prior work on eye movements and pupil measures. We first …

Early Indicators Of Cognitive Dysfunction: The Role Of Mild Behavioral Impairment, Hillary J. Rouse

USF Tampa Graduate Theses and Dissertations

Older age is associated with an increased risk for cognitively impairing diseases such as dementia. Despite significant research to find ways to cure this disease, there has been little success. However, a critical need when an intervention is discovered is a need to find ways to identify people who are at the greatest risk of developing dementia earlier in the disease process so that interventions can be implemented at that time. This could potentially lessen their risk or delay when they are diagnosed. Using longitudinal data from the National Alzheimer’s Coordinating Center (NACC), the aims of this current dissertation were …

Negative Urgency's Influence On State-Level, Emotion-Based Changes In Alcohol-Related Cognitions, Noah Wolkowicz

Graduate Theses and Dissertations

This project expanded on the Acquired Preparedness Model of Risk (APMR) by examining how Negative Urgency (NU), the tendency to act rashly in negative emotional states, affects emotion-based changes in alcohol cognitions to produce risk for alcohol use. The APMR prioritizes the role of outcome expectancies as the means through which traits such as NU, convey alcohol use risk. However, this model treats these cognitions as static and often fails to assess their valence; further, alcohol-cognitions fluctuate in response to negative emotions and may become more salient during these states. Therefore, this study examined: 1) how NU impacts negative emotion-based, …

The Cerebellum's Relationship To Language Function Following Perinatal Stroke, Carolina Alexis Vias

FIU Electronic Theses and Dissertations

While recent studies have demonstrated the association between the cerebellum and higher-order cognitive functioning, it is still unclear how volumetric differences of specific regions of interests within the cerebellum across typical and atypical development are related to language function. We have done so by measuring the volume of cerebellar subregions of healthy controls, and compared the volume to behavioral measures of language function. We then followed with an analysis of the cerebellum’s relationship to language function following perinatal stroke, which provides us with a greater knowledge of the impact of a cortical injury on cerebellar development and the cognitive outcomes …

The Influence Of Mental Fatigue On Sessional Ratings Of Perceived Exertion In Elite Open And Closed Skill Sports Athletes, Joseph O. C. Coyne, Aaron J. Coutts, Robert U. Newton, G. Gregory Haff

Research outputs 2014 to 2021

ABSTRACT: Coyne, JOC, Coutts, AJ, Newton, RU, and Haff, GG. The influence of mental fatigue on sessional ratings of perceived exertion in elite open and closed skill sports athletes. J Strength Cond Res 35(4): 963-969, 2021-The main purpose of this investigation was to examine influence of mental fatigue on sessional ratings of perceived exertion (sRPE) over a training week in elite athletes in open skill (OS, i.e., more unpredictable and externally paced sports) and closed skill (CS, i.e., more predictable and internally paced) sports. Visual analogue scales for mental fatigue, sRPE (CR-10 scale), and training duration were collected from an …

L-Theanine Prevents Long-Term Affective And Cognitive Side Effects Of Adolescent Δ-9-Tetrahydrocannabinol Exposure And Blocks Associated Molecular And Neuronal Abnormalities In The Mesocorticolimbic Circuitry, Marta De Felice, Justine Renard, Roger Hudson, Hanna J. Szkudlarek, Brian J. Pereira, Susanne Schmid, Walter J. Rushlow, Steven R. Laviolette

Brain and Mind Institute Researchers' Publications

Chronic adolescent exposure to Δ-9-tetrahydrocannabinol (THC) is linked to elevated neuropsychiatric risk and induces neuronal, molecular and behavioral abnormalities resembling neuropsychiatric endophenotypes. Previous evidence has revealed that the mesocorticolimbic circuitry, including the prefrontal cortex (PFC) and mesolimbic dopamine (DA) pathway are particularly susceptible to THC-induced pathologic alterations, including dysregulation of DAergic activity states, loss of PFC GABAergic inhibitory control and affective and cognitive abnormalities. There are currently limited pharmacological intervention strategies capable of preventing THC-induced neuropathological adaptations. L-Theanine is an amino acid analog of L-glutamate and L-glutamine derived from various plant sources, including green tea leaves. L-Theanine has previously been …

New Frontiers In Translational Research: Touchscreens, Open Science, And The Mouse Translational Research Accelerator Platform, Jacqueline A. Sullivan, Julie R. Dumont, Sara Memar, Miguel Skirzewski, Jinxia Wan, Maryam H. Mofrad, Hassam Zafar Ansari, Yulong Li, Lyle Muller, Vania F. Prado, Marco A.M. Prado, Lisa M. Saksida, Timothy J. Bussey

Brain and Mind Institute Researchers' Publications

© 2020 International Behavioural and Neural Genetics Society and John Wiley & Sons Ltd Many neurodegenerative and neuropsychiatric diseases and other brain disorders are accompanied by impairments in high-level cognitive functions including memory, attention, motivation, and decision-making. Despite several decades of extensive research, neuroscience is little closer to discovering new treatments. Key impediments include the absence of validated and robust cognitive assessment tools for facilitating translation from animal models to humans. In this review, we describe a state-of-the-art platform poised to overcome these impediments and improve the success of translational research, the Mouse Translational Research Accelerator Platform (MouseTRAP), which is …

The Effect Of Microdosing Classical Psychedelics On Cognitive Performance, Michael Harris

Honors Undergraduate Theses

Public interest and scientific inquiry are currently bringing psychedelic research back into the spotlight after a decades-long respite from clinical human trials. A majority of the research during this recent renaissance has surrounded applications of psychedelics in the fields of mental health. Less attention is being focused to other research areas where psychedelics may also prove informative, such as cognition and information processing. A common trend taking place is the act of administering very small doses of psychedelics as a potential cognitive enhancer, called microdosing. With less research being focused on these areas however, it is not well documented whether …

Occupational Depression, Cognitive Performance, And Task Appreciation: A Study Based On Raven’S Advanced Progressive Matrices, Renzo Bianchi, Irvin Sam Schonfeld

Publications and Research

The Occupational Depression Inventory (ODI) was recently developed to assess depressive symptoms that individuals specifically attribute to their work. Research on the criterion validity of the instrument is still in its infancy. In this study, we examined whether the ODI predicted performance on, and appreciation of, a cognitively challenging test. In light of the link established between clinical depression and neuropsychological impairment, and considering that individuals with depressive symptoms are more likely to feel helpless under challenging circumstances, we hypothesized that occupational depression would be associated with poorer cognitive performance and a darkened appreciation of the task undertaken. We relied …

Why Do You Wear A Mask? Children’S Conceptualizations Of Covid-19 And Contagion Avoidance Behaviors, Emily Hillman

Scripps Senior Theses

With the outbreak of the COVID-19 pandemic, a need has emerged for psychological research on children’s understanding of infectious disease transmission. However, little existing research examines the link between children’s cognitive reasoning about illness and their subsequent behaviors regarding its transmissibility. This study will examine children’s conceptualizations of contagious illnesses such as COVID-19 and their subsequent contagion avoidance. A mixed methods approach will be used to establish the content of children’s conceptualizations of contagion and level of causal reasoning related to illness transmission. Dyads will be constructed comprising 4-12-year-old children and their parents. It is expected that parental contagion avoidance …

What Was Lost: How Dance/Movement Therapy Can Support The Retention And Repair Of Cognitive Abilities In Cancer Patients, A Literature Review, Sarah E. Menser

Expressive Therapies Capstone Theses

This literature review examines research surrounding the effects of chemotherapy on cognitive abilities alongside methods of increasing cognitive functioning throughout treatment. Cancer-related cognitive impairment (CRCI) is seen in many patients undergoing chemotherapy yet has had little attention in cancer research. However, research that has been performed shows that by increasing physical activity during chemotherapy often results in improved cognitive abilities as well as increasing individual’s memory, focus, and multi-tasking abilities. With this connection between physical exercise and cognitive functioning, this author is interested in investigating the idea that dance/movement therapy can assist in the recovery and repair of residual cognitive …

Correlation Between Cognition And Balance Among Middle-Aged And Older Adults Observed Through A Tai Chi Intervention Program, Tao Xiao, Lin Yang, Lee Smith, Paul D. Loprinzi, Nicola Veronese, Jie Yao, Zonghao Zhang, Jane Jie Yu

Faculty and Student Publications

© Copyright © 2020 Xiao, Yang, Smith, Loprinzi, Veronese, Yao, Zhang and Yu. Background: Age-associated decline in cognition and balance may cause severe ability loss for daily living activities among middle-aged and older adults. The relationship between cognition and balance in this aging population remains to be explored. Objective: The present study Is exploratory in nature and aimed to examine the relationship between balance (both static and dynamic components) and global cognitive function among middle-aged and older adults through Tai Chi (TC) practice as a research avenue. Methods: A short-term (12 weeks) intervention of TC was conducted among middle-aged and …

Hypothesized Mechanisms Through Which Exercise May Attenuate Memory Interference, Lindsay K. Crawford, Hong Li, Liye Zou, Gao Xia Wei, Paul D. Loprinzi

Faculty and Student Publications

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. In this paper we introduce a mechanistic model through which exercise may enhance episodic memory, specifically via attenuating proactive and retroactive memory interference. We discuss the various types of memory, different stages of memory function, review the mechanisms behind forgetting, and the mechanistic role of exercise in facilitating pattern separation (to attenuate memory interference).

The Project Talent Twin And Sibling Study: Zygosity And New Data Collection, Carol A. Prescott, Ellen E. Walters, Thalida Em Arpawong, Catalina Zavala, Tara L. Gruenewald, Margaret Gatz

Psychology Faculty Articles and Research

The Project Talent Twin and Sibling (PTTS) study includes 4481 multiples and their 522 nontwin siblings from 2233 families. The sample was drawn from Project Talent, a U.S. national longitudinal study of 377,000 individuals born 1942–1946, first assessed in 1960 and representative of U.S. students in secondary school (Grades 9–12). In addition to the twins and triplets, the 1960 dataset includes 84,000 siblings from 40,000 other families. This design is both genetically informative and unique in facilitating separation of the ‘common’ environment into three sources of variation: shared by all siblings within a family, specific to twin-pairs, and associated with …

Evaluation Of A Cognitive Affective Model Of Physical Activity Behavior, Paul D. Loprinzi, Sara Pazirei, Gina Robinson, Briahna Dickerson, Meghan Edwards, Ryan E. Rhodes

Faculty and Student Publications

© 2020 The Author(s). Background: To empirically evaluate a cognitive affective model of physical activity. This bidirectional, cyclical model hypotheses that executive control processes directly influence habitual engagement in exercise and also directly subserve the exercise-induced affective response to acute exercise associated with future physical activity. Methods: The present study employed a one-week prospective, multi-site design. Participant recruitment and data collection occurred at two separate University sites (one in the United States and the other in Canada). Participants completed a bout of treadmill exercise, with affect and arousal assessed before, during and after the bout of exercise. Subjective and objective …

Acute Exercise On Memory Function: Open Vs. Closed Skilled Exercise, Justin Cantrelle, Grace Burnett, Paul D. Loprinzi

Faculty and Student Publications

© 2020 The Author(s). Background: Previous studies suggest that acute exercise may improve memory function. Few studies, however, have investigated the differential effect of the acute exercise movement patterns on memory. Such an effect is plausible, as research demonstrates that open-skilled exercise (e.g., racquetball) may have a greater effect on memory-related neurotrophins (e.g., brain-derived neurotrophic factors) when compared to closed-skilled exercise (e.g. treadmill exercise). A key distinction between open- and closed-skilled exercise is that open-skilled exercises are those that require an individual to react in a dynamic way to a changing, unpredictable environment. Our aim in this study was to …

Visual Attention And Emotion Regulation In Schizophrenia, Bern Lee

UNLV Theses, Dissertations, Professional Papers, and Capstones

Emotion regulation and emotion processing deficits cut across the varying symptom presentations of schizophrenia. Emotion processing deficits are inadequately treated by pharmacologic interventions and are related to real-world functional impact and disability. This study investigated behavioral and psychophysiological responses to a series of emotion regulation tasks while concurrently collecting eye tracking data as an index of visual attention. A brief neurocognitive assessment was also completed in order to examine potential cognitive determinants of emotion. Participants completed tasks designed to assess cognitive change and directed attention strategies for down-regulation of unpleasant and pleasant emotion. For each of our two unpleasant emotion …