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Articles 1 - 30 of 463
Full-Text Articles in Medicine and Health Sciences
Exploring The Longitudinal Associations Between Diet And Heart Failure With Preserved Ejection Fraction Among Middle-Aged Adults In The Cardia Study, Meaghan Osborne, Dragana Komnenov
Exploring The Longitudinal Associations Between Diet And Heart Failure With Preserved Ejection Fraction Among Middle-Aged Adults In The Cardia Study, Meaghan Osborne, Dragana Komnenov
Medical Student Research Symposium
There is currently limited evidence for the use of pharmacotherapies for heart failure with preserved ejection fraction (HFpEF). Given that diet is a key health behavior, the purpose of this study was to explore dietary predictors of HFpEF among middle-aged adults. All data were obtained from the Coronary Artery Risk Development in Young Adults study, a longitudinal cohort study. We analyzed the data from males and females (n= 2505) who had (1) completed the diet questionnaire at year(Y) 20 of follow-up and (2) undergone Doppler scan at Y30. We then classified participants as having HFpEF or not using three separate …
Maximal Isometric Contraction In Skeletal Muscle Of Endurance Trained Rats With Heart Failure, Dillon Harris, Jacob Kendra, Quinten Pigg, Shadi Golpasandi, Aaron Garcia, Daniela Inoue Yoshimura, Aaron Morton, Mariana Janini Gomes
Maximal Isometric Contraction In Skeletal Muscle Of Endurance Trained Rats With Heart Failure, Dillon Harris, Jacob Kendra, Quinten Pigg, Shadi Golpasandi, Aaron Garcia, Daniela Inoue Yoshimura, Aaron Morton, Mariana Janini Gomes
International Journal of Exercise Science: Conference Proceedings
Heart failure (HF) leads to debilitating skeletal muscle dysfunction and atrophy, with exercise tolerance (ET) remaining a crucial indicator of clinical, practical, and mortality-based outcomes. To simulate these comorbidities, monocrotaline (MCT) is a pharmacological agent typically used to aid in replicating experimental models of right ventricle HF. PURPOSE: To investigate the viability of moderate-intensity aerobic training to preserve skeletal muscle function and ameliorate muscle atrophy in MCT-induced HF. METHODS: Thirty 8-week-old male Wistar rats were randomly divided into sedentary (SED) or trained groups (EX; 30min/day treadmill running sessions, 5 days/wk, for 4 weeks) at 60% intensity determined by a maximal …
Relationship Between Non-Alcoholic Steatohepatitis And Left Ventricular Diastolic Dysfunction In Type 2 Diabetic Patients, Alaa Eldin A. Dawood, Mervat A. Mostafa, Wessam E. El-Shafey, Esraa N. Abo El-Rous, Shimaa K. Zewain
Relationship Between Non-Alcoholic Steatohepatitis And Left Ventricular Diastolic Dysfunction In Type 2 Diabetic Patients, Alaa Eldin A. Dawood, Mervat A. Mostafa, Wessam E. El-Shafey, Esraa N. Abo El-Rous, Shimaa K. Zewain
Menoufia Medical Journal
Objectives: To determine if the poor diastolic function of the left ventricle was independently correlated with hepatic steatosis and fibrosis in type 2 diabetes mellitus (T2DM). Background: There is growing evidence that it is related to nonalcoholic fatty liver disease (NAFLD) and left ventricular diastolic dysfunction (LVDD). We sought to learn more about the relationship between LV diastolic dysfunction and liver fibrosis in T2DM patients. Methods: a case control study was conducted on 100 patients, 50 of them with type 2 diabetes patients without NAFLD and 50 diabetic patients with NAFLD. NAFLD fibrosis score (NFS) and abdominal ultrasonography were used …
Preventing Diabetes Through Prediabetes Screening And Treatment In Primary Care, Dewona Beal
Preventing Diabetes Through Prediabetes Screening And Treatment In Primary Care, Dewona Beal
Doctoral Projects
Diabetes is an epidemic in the United States. There are three types of diabetes: type 1, 2, and gestational diabetes. Type 2 diabetes mellitus (T2DM) is the most common type of diabetes. This type of diabetes can be prevented or delayed. In persons with T2DM, the body cannot use insulin well to keep blood glucose within normal limits. Several factors, including genetics, lifestyle such as poor diet and physical inactivity, obesity, insulin resistance, hormones, and certain medications, can cause it. A precursor to T2DM is prediabetes. Prediabetes is when blood sugar levels are elevated but not elevated enough to be …
Cluster Sets To Prescribe Interval Resistance Training: A Potential Method To Optimise Resistance Training Safety, Feasibility And Efficacy In Cardiac Patients, Kimberley L. Way, Hannah J. Thomas, Lewan Parker, Andrew Maiorana, Michelle A. Keske, David Scott, Jennifer L. Reed, Jessica Tieng, Daniel Hackett, Tess Hawkins, Christopher Latella, Rachael Cordina, Derek L. Tran
Cluster Sets To Prescribe Interval Resistance Training: A Potential Method To Optimise Resistance Training Safety, Feasibility And Efficacy In Cardiac Patients, Kimberley L. Way, Hannah J. Thomas, Lewan Parker, Andrew Maiorana, Michelle A. Keske, David Scott, Jennifer L. Reed, Jessica Tieng, Daniel Hackett, Tess Hawkins, Christopher Latella, Rachael Cordina, Derek L. Tran
Research outputs 2022 to 2026
The integration of resistance training for cardiac patients leads to important health outcomes that are not optimally obtained with aerobic exercise; these include an increase in muscle mass, maintenance of bone mineral density, and improvements in muscular fitness parameters. Despite the proliferation of evidence supporting resistance exercise in recent decades, the implementation of resistance training is underutilised, and prescription is often sub-optimal in cardiac patients. This is frequently associated with safety concerns and inadequate methods of practical exercise prescription. This review discusses the potential application of cluster sets to prescribe interval resistance training in cardiac populations. The addition of planned, …
Triglyceride-Glucose Index, Renal Function And Cardiovascular Disease: A National Cohort Study, Cancan Cui, Lin Liu, Te Zhang, Ling Fang, Zhanhao Mo, Yitian Qi, Jia Zheng, Zhijia Wang, Haikun Xu, Han Yan, Siqi Yue, Xuekui Wang, Zhiyuan Wu
Triglyceride-Glucose Index, Renal Function And Cardiovascular Disease: A National Cohort Study, Cancan Cui, Lin Liu, Te Zhang, Ling Fang, Zhanhao Mo, Yitian Qi, Jia Zheng, Zhijia Wang, Haikun Xu, Han Yan, Siqi Yue, Xuekui Wang, Zhiyuan Wu
Research outputs 2022 to 2026
Background: The triglyceride-glucose (TyG) index is a predictor of cardiovascular diseases; however, to what extent the TyG index is associated with cardiovascular diseases through renal function is unclear. This study aimed to evaluate the complex association of the TyG index and renal function with cardiovascular diseases using a cohort design. Methods: This study included participants from the China Health and Retirement Longitudinal Study (CHARLS) free of cardiovascular diseases at baseline. We performed adjusted regression analyses and mediation analyses using Cox models. The TyG index was calculated as Ln [fasting triglyceride (mg/dL) × fasting glucose (mg/dL)/2]. Renal function was defined by …
Utilizing Stakeholder Input Within The Tennessee Heart Health Network To Improve Cardiovascular Health Outcomes In Tennessee, Abigail C. Bennett
Utilizing Stakeholder Input Within The Tennessee Heart Health Network To Improve Cardiovascular Health Outcomes In Tennessee, Abigail C. Bennett
Longitudinal Scholar's Project
Background: Tennessee ranks sixth nationwide for most deaths related to heart disease. The Tennessee Heart Health Network (TN-HHN), an initiative coordinated by the Tennessee Population Health Consortium (TN-PHC), was created to combat this issue. The TN-HHN is a statewide network of primary care practices, health systems, and academic centers committed to implementing patient-centered outcomes research (PCOR) approaches to demonstrably improve cardiovascular disease (CVD) health outcomes and health equity across Tennessee.
Objective: Evaluate stakeholder experiences in participating in the Network in an effort to assess partner satisfaction and improve the TN-HHN as a whole.
Methods: Eligible stakeholders were invited via …
Assessment Of Preoperative Anxiety, Its Contributing Factors, And Impact On Immediate Postoperative Outcomes Among Cardiac Surgery Patients - A Cross-Sectional Study, Naveen Nizar Ali
Theses & Dissertations
Background: Preoperative anxiety is characterized by an intense sensation of fear, apprehension, and nervousness. In the domain of cardiac surgery, the assessment and management of preoperative anxiety is of paramount importance, as it plays a pivotal role in shaping the patient's surgical experience and immediate postoperative outcomes. While the etiology of preoperative anxiety is multifaceted, the influence of sociodemographic factors in this context is of paramount importance. However, limited studies have been conducted in developing countries regarding this phenomenon.
Purpose: The study aimed to identify the frequency of preoperative anxiety, its contributing factors, and its impact on immediate postoperative outcomes …
Contaminant Metals And Cardiovascular Health, Karl Kristian Lundin, Yusuf Kamran Qadeer, Zhen Wang, Salim S. Virani, Roman Leischik, Carl J. Lavie, Markus Strauss, Chayakrit Krittanawong
Contaminant Metals And Cardiovascular Health, Karl Kristian Lundin, Yusuf Kamran Qadeer, Zhen Wang, Salim S. Virani, Roman Leischik, Carl J. Lavie, Markus Strauss, Chayakrit Krittanawong
Office of the Provost
A growing body of research has begun to link exposure to environmental contaminants, such as heavy metals, with a variety of negative health outcomes. In this paper, we sought to review the current research describing the impact of certain common contaminant metals on cardiovascular (CV) health. We reviewed ten metals: lead, barium, nickel, chromium, cadmium, arsenic, mercury, selenium, zinc, and copper. After a literature review, we briefly summarized the routes of environmental exposure, pathophysiological mechanisms, CV health impacts, and exposure prevention and/or mitigation strategies for each metal. The resulting article discloses a broad spectrum of pathological significance, from relatively benign …
Cardiac Rehabilitation In Abu Dhabi: A Retrospective Investigation Of Program Delivery, Participants, And Factors Associated With Program Completion Utilizing A Hospital Registry, Aaron Heisey Thrush
Cardiac Rehabilitation In Abu Dhabi: A Retrospective Investigation Of Program Delivery, Participants, And Factors Associated With Program Completion Utilizing A Hospital Registry, Aaron Heisey Thrush
Journal of the Saudi Heart Association
Objectives: Investigations into the provision of cardiac rehabilitation from the Arabian Gulf countries are rare, despite suffering from an unusually high prevalence of cardiovascular disease. This study reports patient and program characteristics from an exercise-based cardiac rehabilitation program in Abu Dhabi, and factors associated with program completion. Methods: Data was drawn from the institution’s cardiac rehabilitation registry, populated from the electronic medical record of patients enrolled in the hospital-based cardiac rehabilitation program, from 2015 to 2022. The program was administered by physical therapist and nurse specialists and guided by individualized exercise parameters. Completion of the program was defined as attendance …
The Prevention And Cardiac Rehabilitation Group Of The Saudi Heart Association Recommendations Regarding Establishing A Cardiac Rehabilitation Service, Abdulhalim Jamal Kinsara, Raghdah Aljehani, Jadwiga Wolszakiewicz, Adam Staron, Muteb A. Alsulaimy
The Prevention And Cardiac Rehabilitation Group Of The Saudi Heart Association Recommendations Regarding Establishing A Cardiac Rehabilitation Service, Abdulhalim Jamal Kinsara, Raghdah Aljehani, Jadwiga Wolszakiewicz, Adam Staron, Muteb A. Alsulaimy
Journal of the Saudi Heart Association
Cardiac rehabilitation (CR) is a cornerstone in the secondary prevention of cardiovascular disease (CVD). Comprehensive cardiac rehabilitation has obtained the highest class of recommendation and the level of evidence for the treatment of patients with ST-segment elevation myocardial infarction, after myocardial revascularization, with chronic coronary syndromes, and in patients with heart failure (HF). Comprehensive cardiac rehabilitation should be implemented as soon as possible, be multi-phasic, and adjusted to the individual needs of the patient. CR is still suboptimally used, and many cardiac centers do not have such services (2). The provision of CR services should be based on standards and …
Association Between Historical Neighborhood Redlining And Cardiovascular Outcomes Among Us Veterans With Atherosclerotic Cardiovascular Diseases, Salil V. Deo, Issam Motairek, Khurram Nasir, Amgad Mentias, Yakov Elgudin, Salim S. Virani, Sanjay Rajagopalan, Sadeer Al-Kindi
Association Between Historical Neighborhood Redlining And Cardiovascular Outcomes Among Us Veterans With Atherosclerotic Cardiovascular Diseases, Salil V. Deo, Issam Motairek, Khurram Nasir, Amgad Mentias, Yakov Elgudin, Salim S. Virani, Sanjay Rajagopalan, Sadeer Al-Kindi
Office of the Provost
Importance: In the 1930s, the government-sponsored Home Owners' Loan Corporation (HOLC) established maps of US neighborhoods that identified mortgage risk (grade A [green] characterizing lowest-risk neighborhoods in the US through mechanisms that transcend traditional risk factors to grade D [red] characterizing highest risk). This practice led to disinvestments and segregation in neighborhoods considered redlined. Very few studies have targeted whether there is an association between redlining and cardiovascular disease.
Objective: To evaluate whether redlining is associated with adverse cardiovascular outcomes in US veterans.
Design, setting, and participants: In this longitudinal cohort study, US veterans were followed up (January 1, 2016, …
Utilizing Mhealth To Increase Follow-Up In Latinx Adults With Hyperlipidemia., Jessica Raymond Richards
Utilizing Mhealth To Increase Follow-Up In Latinx Adults With Hyperlipidemia., Jessica Raymond Richards
Doctor of Nursing Practice Papers
Background: Management of hyperlipidemia (HLD) is crucial to the prevention and management of cardiovascular disease cardiovascular disease (CVD), a leading cause of death in the United States (US) and Latinx adults (Centers for Disease Control and Prevention (CDC), 2019). The main difficulty affecting monitoring of lipid levels in patients diagnosed with HLD is lack of adherence to follow-up appointments.
Purpose: The purpose of this Quality Improvement (QI) project is to evaluate the impact of culturally competent translated short message service (SMS) texts to increase adherence follow-up on a Latinx population served at the Kentucky Racing Services Health Center (KRSHC).
Intervention: …
Covid-19 Severity And Cardiovascular Outcomes In Sars-Cov-2-Infected Patients With Cancer And Cardiovascular Disease, Melissa Y.Y. Moey, Cassandra Hennessy, Benjamin French, Jeremy L. Warner, Matthew D. Tucker, Daniel J. Hausrath, Dimpy P. Shah, Jeanne M. Decara, Ziad Bakouny, Chris Labaki, Toni K. Choueiri, Susan Dent, Nausheen Akhter, Roohi Ismail-Khan, Lisa Tachiki, David Slosky, Tamar S. Polonsky, Joy A. Awosika, Audrey Crago, Trisha Wise-Draper, Nino Balanchivadze, Clara Hwang, Leslie A. Fecher, Cyndi Gonzalez Gomez, Brandon Hayes-Lattin, Michael J. Glover, Sumit A. Shah, Dharmesh Gopalakrishnan, Elizabeth A. Griffiths, Daniel H. Kwon, Vadim S. Koshkin, Sana Mahmood, Babar Bashir, Taylor Nonato, Pedram Razavi, Rana R. Mckay, Gayathri Nagaraj, Eric Oligino, Matthew Puc, Polina Tregubenko, Elizabeth M. Wulff-Burchfield, Zhuoer Xie, Thorvardur R. Halfdanarson, Dimitrios Farmakiotis, Elizabeth J. Klein, Elizabeth V. Robilotti, Gregory J. Riely, Jean-Bernard Durand, Salim S. Hayek, Lavanya Kondapalli, Stephanie Berg, Timothy E. O'Connor, Mehmet A. Bilen, Cecilia Castellano, Melissa K. Accordino, Blau Sibel, Lisa B. Weissmann, Chinmay Jani, Daniel B. Flora, Lawrence Rudski, Miriam Santos Dutra, Bouganim Nathaniel, Erika Ruíz-García, Diana Vilar-Compte, Shilpa Gupta, Alicia Morgans, Anju Nohria
Covid-19 Severity And Cardiovascular Outcomes In Sars-Cov-2-Infected Patients With Cancer And Cardiovascular Disease, Melissa Y.Y. Moey, Cassandra Hennessy, Benjamin French, Jeremy L. Warner, Matthew D. Tucker, Daniel J. Hausrath, Dimpy P. Shah, Jeanne M. Decara, Ziad Bakouny, Chris Labaki, Toni K. Choueiri, Susan Dent, Nausheen Akhter, Roohi Ismail-Khan, Lisa Tachiki, David Slosky, Tamar S. Polonsky, Joy A. Awosika, Audrey Crago, Trisha Wise-Draper, Nino Balanchivadze, Clara Hwang, Leslie A. Fecher, Cyndi Gonzalez Gomez, Brandon Hayes-Lattin, Michael J. Glover, Sumit A. Shah, Dharmesh Gopalakrishnan, Elizabeth A. Griffiths, Daniel H. Kwon, Vadim S. Koshkin, Sana Mahmood, Babar Bashir, Taylor Nonato, Pedram Razavi, Rana R. Mckay, Gayathri Nagaraj, Eric Oligino, Matthew Puc, Polina Tregubenko, Elizabeth M. Wulff-Burchfield, Zhuoer Xie, Thorvardur R. Halfdanarson, Dimitrios Farmakiotis, Elizabeth J. Klein, Elizabeth V. Robilotti, Gregory J. Riely, Jean-Bernard Durand, Salim S. Hayek, Lavanya Kondapalli, Stephanie Berg, Timothy E. O'Connor, Mehmet A. Bilen, Cecilia Castellano, Melissa K. Accordino, Blau Sibel, Lisa B. Weissmann, Chinmay Jani, Daniel B. Flora, Lawrence Rudski, Miriam Santos Dutra, Bouganim Nathaniel, Erika Ruíz-García, Diana Vilar-Compte, Shilpa Gupta, Alicia Morgans, Anju Nohria
Kimmel Cancer Center Faculty Papers
BACKGROUND: Data regarding outcomes among patients with cancer and co-morbid cardiovascular disease (CVD)/cardiovascular risk factors (CVRF) after SARS-CoV-2 infection are limited.
OBJECTIVES: To compare Coronavirus disease 2019 (COVID-19) related complications among cancer patients with and without co-morbid CVD/CVRF.
METHODS: Retrospective cohort study of patients with cancer and laboratory-confirmed SARS-CoV-2, reported to the COVID-19 and Cancer Consortium (CCC19) registry from 03/17/2020 to 12/31/2021. CVD/CVRF was defined as established CVD
RESULTS: Among 10,876 SARS-CoV-2 infected patients with cancer (median age 65 [IQR 54-74] years, 53% female, 52% White), 6253 patients (57%) had co-morbid CVD/CVRF. Co-morbid CVD/CVRF was associated with higher COVID-19 severity …
Nanoparticle Approaches For The Renin-Angiotensin System, Sajini D. Hettiarachchi, Young M. Kwon, Yadollah Omidi, Robert C. Speth
Nanoparticle Approaches For The Renin-Angiotensin System, Sajini D. Hettiarachchi, Young M. Kwon, Yadollah Omidi, Robert C. Speth
HPD Articles
The renin-angiotensin system (RAS) is a hormonal cascade that contributes to several disorders: systemic hypertension, heart failure, kidney disease, and neurodegenerative disease. Activation of the RAS can promote inflammation and fibrosis. Drugs that target the RAS can be classified into 3 categories, AT1 angiotensin receptor blockers (ARBs), angiotensin-converting enzyme (ACE) inhibitors, and renin inhibitors. The therapeutic efficacy of current RAS-inhibiting drugs is limited by poor penetration across the blood-brain barrier, low bioavailability, and to some extent, short half-lives. Nanoparticle-mediated drug delivery systems (DDSs) are possible emerging alternatives to overcome such limitations. Nanoparticles are ideally 1-100 nm in size and are …
Causal Associations Of Air Pollution With Cardiovascular Disease And Respiratory Diseases Among Elder Diabetic Patients, Zhiwei Li, Shiyun Lv, Feng Lu, Moning Guo, Zhiyuan Wu, Yue Liu, Weiming Li, Mengmeng Liu, Siqi Yu, Yanshuang Jiang, Bo Gao, Xiaonan Wang, Xia Li, Wei Wang, Xiangtong Liu, Xiuhua Guo
Causal Associations Of Air Pollution With Cardiovascular Disease And Respiratory Diseases Among Elder Diabetic Patients, Zhiwei Li, Shiyun Lv, Feng Lu, Moning Guo, Zhiyuan Wu, Yue Liu, Weiming Li, Mengmeng Liu, Siqi Yu, Yanshuang Jiang, Bo Gao, Xiaonan Wang, Xia Li, Wei Wang, Xiangtong Liu, Xiuhua Guo
Research outputs 2022 to 2026
Extensive researches have linked air pollutants with cardiovascular disease (CVD) and respiratory diseases (RD), however, there is limited evidence on causal effects of air pollutants on morbidity of CVD or RD with comorbidities, particularly diabetes mellitus in elder patients. We included hospital admissions for CVD or RD among elder ( ≥ 65 years) diabetic patients between 2014 and 2019 in Beijing. A time-stratified case-crossover design based on negative-control exposure was used to assess causal associations of short-term exposure to air pollutants with CVD and RD among diabetic patients with the maximum lag of 7 days. A random forest regression model …
Low Educational Attainment Is Associated With Higher All-Cause And Cardiovascular Mortality In The United States Adult Population, Najah Khan, Zulqarnain Javed, Isaac Acquah, Kobina Hagan, Madiha Khan, Javier Valero-Elizondo, Ryan Chang, Umair Javed, Mohamad B. Taha, Salim S. Virani
Low Educational Attainment Is Associated With Higher All-Cause And Cardiovascular Mortality In The United States Adult Population, Najah Khan, Zulqarnain Javed, Isaac Acquah, Kobina Hagan, Madiha Khan, Javier Valero-Elizondo, Ryan Chang, Umair Javed, Mohamad B. Taha, Salim S. Virani
Office of the Provost
Introduction: Educational attainment is an important social determinant of health (SDOH) for cardiovascular disease (CVD). However, the association between educational attainment and all-cause and CVD mortality has not been longitudinally evaluated on a population-level in the US, especially in individuals with atherosclerotic cardiovascular disease (ASCVD). In this nationally representative study, we assessed the association between educational attainment and the risk of all-cause and cardiovascular (CVD) mortality in the general adult population and in adults with ASCVD in the US.
Methods: We used data from the 2006-2014 National Death Index-linked National Health Interview Survey for adults ≥ 18 years. We generated …
A Rapid Review Of The Literature: Cardiovascular Disease Preventive Practices And Rural Black Women, Modjadji M. Choshi, Maria Devalpine
A Rapid Review Of The Literature: Cardiovascular Disease Preventive Practices And Rural Black Women, Modjadji M. Choshi, Maria Devalpine
Virginia Journal of Public Health
Cardiovascular disease (CVD) is the leading cause of death among Black/African American women. Rural Black women have the highest CVD prevalence and are more likely to have modifiable risk factors such as high blood pressure, diabetes, and obesity than any other race. Accessible evidence-based culture-appropriate self-care programs for risk reduction and CVD prevention can address these disparities. This rapid review aims to provide a comprehensive collection of such programs. Methods. Searches were performed in PubMed, CINAHL, Web of Science, Psychinfo-Embase, and Scopus for studies reporting CVD prevention programs for rural Black women. Three articles met the inclusion criteria, with …
The Impact Of Personal Barriers To Incorporating The American Heart Association Diet, Aaron Bigando
The Impact Of Personal Barriers To Incorporating The American Heart Association Diet, Aaron Bigando
Doctor of Nursing Practice Scholarly Project
The leading cause of death worldwide is cardiovascular disease. Diet is the most influential, modifiable factor related to the development and progression of cardiovascular disease. The American Heart Association developed a diet that delivers guidelines for diet. Therefore, identifying the most significant factors that hinder the effectiveness of the diet was necessary. These hindrances can be categorized as physical, psychosocial, and socioeconomic barriers. Demographic differences also impact diet.
A survey was developed to identify and account for the most common dietary barriers. The Barriers to Healthy Eating scale addressed different circumstances which impact diet. By using this scale, providers can …
Artificial Intelligence Modelling To Assess The Risk Of Cardiovascular Disease In Oncology Patients., Samer S Al-Droubi, Eiman Jahangir, Karl M Kochendorfer, Marianna Krive, Michal Laufer-Perl, Dan Gilon, Tochukwu M Okwuosa, Christopher P Gans, Joshua H Arnold, Shakthi T Bhaskar, Hesham A Yasin, Jacob Krive
Artificial Intelligence Modelling To Assess The Risk Of Cardiovascular Disease In Oncology Patients., Samer S Al-Droubi, Eiman Jahangir, Karl M Kochendorfer, Marianna Krive, Michal Laufer-Perl, Dan Gilon, Tochukwu M Okwuosa, Christopher P Gans, Joshua H Arnold, Shakthi T Bhaskar, Hesham A Yasin, Jacob Krive
HPD Articles
AIMS: There are no comprehensive machine learning (ML) tools used by oncologists to assist with risk identification and referrals to cardio-oncology. This study applies ML algorithms to identify oncology patients at risk for cardiovascular disease for referrals to cardio-oncology and to generate risk scores to support quality of care.
METHODS AND RESULTS: De-identified patient data were obtained from Vanderbilt University Medical Center. Patients with breast, kidney, and B-cell lymphoma cancers were targeted. Additionally, the study included patients who received immunotherapy drugs for treatment of melanoma, lung cancer, or kidney cancer. Random forest (RF) and artificial neural network (ANN) ML models …
How Can Consuming A Plant-Based Diet Reduce The Risk Of Cardiovascular Disease In Postmenopausal Women?, Rebecca Stack
How Can Consuming A Plant-Based Diet Reduce The Risk Of Cardiovascular Disease In Postmenopausal Women?, Rebecca Stack
Honors Program Theses and Projects
Despite the fact that women suffer higher rates of cardiovascular events after menopause, there exists a significant underrepresentation of women—especially postmenopausal women—in cardiovascular clinical trials to date. Fortunately, current evidence reveals that cardiovascular events in the general population are largely preventable through modifiable lifestyle factors, with dietary intervention being one of the most important (Amiri et al., 2022). As the impact of whole-diet interventions on cardiovascular risk factors is further explored, it has been determined that a plant-based dietary pattern may favorably influence the prevention of cardiovascular events in postmenopausal women (Barańska et al., 2021). Evidence also reveals that certain …
Review Of Cardiovascular Risk Of Androgen Deprivation Therapy And The Influence Of Race In Men With Prostate Cancer, James Fradin, Felix J. Kim, Grace Lu-Yao, Eugene Storozynsky, William K. Kelly
Review Of Cardiovascular Risk Of Androgen Deprivation Therapy And The Influence Of Race In Men With Prostate Cancer, James Fradin, Felix J. Kim, Grace Lu-Yao, Eugene Storozynsky, William K. Kelly
Department of Medical Oncology Faculty Papers
Androgen deprivation therapy is the cornerstone of prostate cancer therapy. Recent studies have revealed an association between androgen deprivation therapy and cardiovascular adverse effects such as myocardial infarction and stroke. This review summarizes the available research on the cardiovascular risk of men using androgen deprivation therapy. We also discuss racial disparities surrounding both prostate cancer and cardiovascular disease, emphasizing the importance of biological/molecular and socioeconomic factors in assessing baseline risk in patients beginning androgen ablation. Based on the literature, we provide recommendations for monitoring patients who are at high risk for a cardiovascular adverse event while being treated on androgen …
History Of Hypertension And Urinary Incontinence Among Adults Aged 40 And Older: A Cross-Sectional Study From The National Health And Nutrition Examination Survey, Puthyda Keath, Karla Cordova Nicolas
History Of Hypertension And Urinary Incontinence Among Adults Aged 40 And Older: A Cross-Sectional Study From The National Health And Nutrition Examination Survey, Puthyda Keath, Karla Cordova Nicolas
OHSU-PSU School of Public Health Annual Conference
Introduction: Urinary incontinence (UI) impacts over 200 million individuals world-wide, though little is known about the causes of this condition. The aim of this cross-sectional study was to examine prevalence of UI and the association between a history of hypertension and UI in older adults. A secondary aim was to determine if sex modified the association between history of hypertension and UI.
Methods: This study utilized data from the U.S. National Health and Nutrition Examination Survey (NHANES) 2011-2016 cycles. We included 9,717 U.S adults (≥40 years) with complete information on history of hypertension, UI and other independent variables. Participants with …
High Prevalence Of Cardiometabolic Risk Factors Amongst Young Adults In The United Arab Emirates: The Uae Healthy Future Study, Fatima Mezhal, Abderrahim Oulhaj, Abdishakur Abdulle, Abdulla Aljunaibi, Abdulla Alnaeemi, Amar Ahmad, Andrea Leinberger-Jabari, Ayesha S. Al Dhaheri, Eiman Alzaabi, Fatma Al-Maskari, Fatme Alanouti, Fayza Alameri, Habiba Alsafar, Hamad Alblooshi, Juma Alkaabi, Laila Abdel Wareth, Mai Aljaber, Marina Kazim, Michael Weitzman, Mohammad Al-Houqani, Mohammad Hag Ali, E. Murat Tuzcu, Naima Oumeziane, Omar El-Shahawy, Rami H. Al-Rifai, Scott Sherman, Syed M. Shah, Thekra Alzaabi, Tom Loney, Wael Almahmeed
High Prevalence Of Cardiometabolic Risk Factors Amongst Young Adults In The United Arab Emirates: The Uae Healthy Future Study, Fatima Mezhal, Abderrahim Oulhaj, Abdishakur Abdulle, Abdulla Aljunaibi, Abdulla Alnaeemi, Amar Ahmad, Andrea Leinberger-Jabari, Ayesha S. Al Dhaheri, Eiman Alzaabi, Fatma Al-Maskari, Fatme Alanouti, Fayza Alameri, Habiba Alsafar, Hamad Alblooshi, Juma Alkaabi, Laila Abdel Wareth, Mai Aljaber, Marina Kazim, Michael Weitzman, Mohammad Al-Houqani, Mohammad Hag Ali, E. Murat Tuzcu, Naima Oumeziane, Omar El-Shahawy, Rami H. Al-Rifai, Scott Sherman, Syed M. Shah, Thekra Alzaabi, Tom Loney, Wael Almahmeed
All Works
BackgroundCardiovascular disease (CVD) is the leading cause of death in the world. In the United Arab Emirates (UAE), it accounts for 40% of mortality. CVD is caused by multiple cardiometabolic risk factors (CRFs) including obesity, dysglycemia, dyslipidemia, hypertension and central obesity. However, there are limited studies focusing on the CVD risk burden among young Emirati adults. This study investigates the burden of CRFs in a sample of young Emiratis, and estimates the distribution in relation to sociodemographic and behavioral determinants.MethodsData was used from the baseline data of the UAE Healthy Future Study volunteers. The study participants were aged 18 to …
New Egfr Equations: Implications For Cardiologists And Racial Inequities, Nali Gillespie, Rajesh Mohandas
New Egfr Equations: Implications For Cardiologists And Racial Inequities, Nali Gillespie, Rajesh Mohandas
School of Medicine Faculty Publications
Recently, a new equation to predict estimated glomerular filtration rate (eGFR) that does not include a variable for race has been endorsed by professional organizations and increasingly adopted by clinical laboratories. We discuss the reasoning behind the development of the new equation, implications for cardiologists, and how the new eGFR equation could impact disparities in the cardiovascular care of these patients. Race, a social construct, is a poor proxy for biological variability. Clinical trials which recruit underrepresented minorities and advances in genomic medicine could accelerate the development of personalized medicine and help decrease inequalities in clinical outcomes.
It's Time To (Again) Recognize The Considerable Clinical And Public Health Significance Of Cardiorespiratory Fitness, Leonard A. Kaminsky, Mary T. Imboden, Cemal Ozemek
It's Time To (Again) Recognize The Considerable Clinical And Public Health Significance Of Cardiorespiratory Fitness, Leonard A. Kaminsky, Mary T. Imboden, Cemal Ozemek
Faculty Publications - Department of Kinesiology
In this issue of the Journal of the American College of Cardiology, Kokkinos et al5 studied the relationship of both a single CRF value, and change in CRF, with all-cause mortality in a large (n 1⁄4 93,060) sample from the ETHOS (Exercise Testing and Health Outcomes Study) cohort. In this cohort, CRF was estimated as the peak metabolic equivalents (METs) derived from the peak speed and grade obtained on a treadmill exercise test. The findings from the single measure of CRF showed, compared with the low-CRF group (w5 METs), reductions in mortality rate across each higher-CRF group in both those …
Serum Cotinine As A Predictor Of Lipid-Related Indices In Turkish Immigrants With Type 2 Diabetes: A Clinic-Based Cross-Sectional Study, Shiryn D. Sukhram, Gustavo G. Zarini, Lemia H. Shaban, Joan A. Vaccaro, Avinash R. Sukhram, Fatma G. Huffman
Serum Cotinine As A Predictor Of Lipid-Related Indices In Turkish Immigrants With Type 2 Diabetes: A Clinic-Based Cross-Sectional Study, Shiryn D. Sukhram, Gustavo G. Zarini, Lemia H. Shaban, Joan A. Vaccaro, Avinash R. Sukhram, Fatma G. Huffman
Publications and Research
Background: Turkish immigrants form the largest ethnic minority group in the
Netherlands and show a higher prevalence of (i) cardiovascular disease (CVD),
(ii) cigarette smoking, and (iii) type 2 diabetes (T2D) as compared to the native
Dutch. This study examines the association of CVD risk factors: serum cotinine, as
an indicator of cigarette smoke, and lipid-related indices among first-generation
(foreign-born) Turkish immigrants with T2D living in deprived neighbourhoods in the
Netherlands.
Methods: A total of 110 participants, physician-diagnosed with T2D, aged 30 years
and older, were recruited by convenience sampling from the Schilderswijk
neighbourhood of The Hague in a clinic-based …
Disparities In Contraception In Women With Cardiovascular Diseases In The Cardiac-Obstetrical Clinic, Laura Fiorini, Maria De Abreu Pineda, Jason K. Baxter, Rebekah J. Mccurdy, Andria Jones, Indranee Rajapreyar, Amanda Roman-Camargo
Disparities In Contraception In Women With Cardiovascular Diseases In The Cardiac-Obstetrical Clinic, Laura Fiorini, Maria De Abreu Pineda, Jason K. Baxter, Rebekah J. Mccurdy, Andria Jones, Indranee Rajapreyar, Amanda Roman-Camargo
Department of Obstetrics and Gynecology Posters
Objective
- National Survey of Family Growth 2017-19 survey reported a 65.3% contraceptive use:
- 18% tubal, 5.6% vasectomy
- 18% hormonal therapy
- 8.4% intrauterine devices (IUD)
- 8.4% condoms
- To evaluate postpartum contraception plans and use in pregnant women with cardiovascular disease (CVD) after visits to the combined cardio-obstetric clinic
Modifiable Health Disparities And Cardiovascular Disease Risk Factors In Latino Migrant Seasonal Farmworkers: A Meta-Analysis, Cindy Mendez
Modifiable Health Disparities And Cardiovascular Disease Risk Factors In Latino Migrant Seasonal Farmworkers: A Meta-Analysis, Cindy Mendez
Nursing Theses and Dissertations
BACKGROUND: Cardiovascular disease is the leading cause of death in the United States (U.S.). Existing literature concluded that Latino migrant seasonal farmworkers endure higher rates of adverse health disparities and chronic diseases than the general U.S. population. However, research on the Latino migrant seasonal farmworkers’ modifiable health disparities (i.e., alcohol use and smoking) and cardiovascular disease risk factors (i.e., high cholesterol, diabetes mellitus, hypertension, and overweight/obesity) is scarce, particularly studies comparing male and female Latino migrant seasonal farmworkers. PURPOSE: This meta-analysis had two aims. First, examine whether male or female Latino migrant seasonal farmworkers in the U.S. have …
Effects Of A Residential Lifestyle Intervention Program On Selected Lipid Measures And Nutritional Choices, Delores M. Rugless
Effects Of A Residential Lifestyle Intervention Program On Selected Lipid Measures And Nutritional Choices, Delores M. Rugless
DNP Research Projects
Abstract
Objective: Cardiovascular disease has been the leading cause of death since the early 1920s. As with other chronic diseases, cardiovascular disease is primarily influenced by behaviors and the environment, with poor nutrition being a major contributing factor. Despite knowing the importance of lifestyle modification to manage cardiovascular disease effectively, many individuals have difficulty adhering to lifestyle modification principles. Residential lifestyle modification centers provide the education and support necessary to assist individuals with implementing behavioral changes. This DNP project aimed to demonstrate the value of diet modification implemented at a residential lifestyle center to decrease specific cardiovascular risk factors. Method: …