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Full-Text Articles in Medicine and Health Sciences

Characterization Of The Anti-Angiogenic Properties Of Kdr-Ig4-7 And Its Variants As Potential Anti-Cancer Therapeutics, Jang Pyo Park Dec 2007

Characterization Of The Anti-Angiogenic Properties Of Kdr-Ig4-7 And Its Variants As Potential Anti-Cancer Therapeutics, Jang Pyo Park

All Dissertations

Beginning with the development of an embryo and throughout one's adult life angiogenesis plays an essential role for organ growth and repair. The balancing of pro-angiogenic factors to anti-angiogenic factors is what regulates the process of angiogenesis. When this balance is disrupted in one direction or the other, numerous disorders can occur including ocular and inflammatory diseases and, in particular, tumor growth and metastasis. Therefore, inhibition of angiogenesis has become an effective therapy for arresting the growth of tumors.
A key regulator of angiogenesis involves vascular endothelial growth factor (VEGF) and its receptor, VEGFR-2 (KDR). The binding of VEGF to …


Urban Versus Rural Patterns Of Mammography Use: An Analysis Of Two Southeastern States, Valerie Miranda Bycott Oct 2007

Urban Versus Rural Patterns Of Mammography Use: An Analysis Of Two Southeastern States, Valerie Miranda Bycott

Public Health Theses

Mammography is widely recognized as the best method to detect breast cancer. This study examined the screening rate differences among women who live in urban and rural counties in Georgia and North Carolina. Data on the mammography screening rates was obtained from the Behavior Risk Factor Surveillance System (BRFSS) for 2002 and 2004. To assess the availability of mammography facilities, data was obtained from the Mammography Facility Database provided by the FDA. Multivariate logistic regression showed that having a usual source of care in urban counties was a positive predictor of women 40-59 years of age getting screened in both …