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Full-Text Articles in Medicine and Health Sciences
Dual Functional Magnetic Nanoparticles Conjugated With Carbon Quantum Dots For Hyperthermia And Photodynamic Therapy For Cancer, Mounika Choppadandi, Kondi Soumya, Sumanta Ghosh, Aishwarya Balu, Tanvi Shingote, Srivalliputtur Sarath Babu, Vani Sai Prasanna, Somasundaram Arumugam, Ravichandiran Velyutham, Murali M. Yallapu, Govinda Kapusetti
Dual Functional Magnetic Nanoparticles Conjugated With Carbon Quantum Dots For Hyperthermia And Photodynamic Therapy For Cancer, Mounika Choppadandi, Kondi Soumya, Sumanta Ghosh, Aishwarya Balu, Tanvi Shingote, Srivalliputtur Sarath Babu, Vani Sai Prasanna, Somasundaram Arumugam, Ravichandiran Velyutham, Murali M. Yallapu, Govinda Kapusetti
School of Medicine Publications and Presentations
The global incidence of cancer continues to rise, posing a significant public health concern. Although numerous cancer therapies exist, each has limitations and complications. The present study explores alternative cancer treatment approaches, combining hyperthermia and photodynamic therapy (PDT). Magnetic nanoparticles (MNPs) and amine-functionalized carbon quantum dots (A-CQDs) were synthesized separately and then covalently conjugated to form a single nanosystem for combinational therapy (M-CQDs). The successful conjugation was confirmed using zeta potential, Fourier transform infrared spectroscopy (FT-IR), and UV-visible spectroscopy. Morphological examination in transmission electron microscopy (TEM) further verified the conjugation of CQDs with MNPs. Energy dispersive X-ray spectroscopy (EDX) revealed …
Nebulization Based Inhalation Nanomedicine For Lung Cancer Treatments, Rahul Tiwari, Meghana Kolli, Neeraj Chauhan, Eswara Naga Hanuma, Vivek Kashyap, Subhash Chauhan, Murali Yallapu
Nebulization Based Inhalation Nanomedicine For Lung Cancer Treatments, Rahul Tiwari, Meghana Kolli, Neeraj Chauhan, Eswara Naga Hanuma, Vivek Kashyap, Subhash Chauhan, Murali Yallapu
Research Symposium
Background: Lung cancer is reported to have a high incidence rate and first leading cause of cancer-related morbidity and mortality across the world including in the United States. Noninvasive nebulized inhalation is a promising delivery strategy for lung, which can enhance the targeting efficiency and detention time interval of nanoparticles in the lung tissue, thus elevating the therapeutic index of therapeutic agent(s) at lower dosages. The aim of this study is to develop inhalable nanoparticles (INPs) for effective delivery of therapeutic agents in lung cancer cell lines and ex vivo models.
Methods: The inhalation nanoparticles (INPs) were prepared by solvent …
Engaging The South Texas Latino Community: Utilizing Community Member Feedback To Inform Research On Community Engagement, Dolores Garcia, Rebecca Jones, Sonia Rincon-Sanchez, Paula Bravo
Engaging The South Texas Latino Community: Utilizing Community Member Feedback To Inform Research On Community Engagement, Dolores Garcia, Rebecca Jones, Sonia Rincon-Sanchez, Paula Bravo
Research Symposium
Background: The UT Health San Antonio Mays Cancer Center Community Outreach and Engagement Core is identifying how South Texas Latino residents navigate cancer-related health needs. Our team explored these from a class and place perspective.
Methods: Listening sessions were conducted across South Texas. Sessions lasted 1.5 hours, were in English and Spanish, and recorded. Recordings were transcribed, and a thematic analysis was completed.
Results: Seventy-four South Texas residents participated in the sessions.
Insurance status and healthcare access were key factors impacting communities’ ability to navigate cancer-related health needs. Analyses were explored from an urban, rural, inland, and border perspective.
Urban …