Medicine and Health Sciences Commons^™

Developing An Online Questionnaire To Investigate The Covid-19 Pandemic’S Impacts On Social Isolation And Health In Older Adults Living With Multimorbidity: A Pilot Study, Patricia Nistor

Electronic Thesis and Dissertation Repository

Introduction. Social restrictions preventing the spread of COVID-19 possibly increased social isolation and loneliness. The validity and reliability of a questionnaire assessing the COVID-19 pandemic’s impact on social isolation and loneliness in community dwelling older adults with multimorbidity was investigated.

Methods. A conceptual framework was developed to guide questionnaire construction. Participants were recruited through professional networks, comprising a convenience sample. Feedback interviews assessed usability and face validity. Content validity was assessed using a Content Validity Matrix, and construct validity through tests of association. Reliability of validated scales was assessed using Cronbach’s ⍺. Descriptive statistics and logistic regression were computed. …

Social Connectedness, Adolescent Mental Health And Well-Being At The Later Stages Of The Covid-19 Pandemic: A Mixed Methods Exploration, Sarah Abdunnabi

Electronic Thesis and Dissertation Repository

COVID-19 posed novel challenges by limiting in-person interactions and shifting interactions online. Effects of online and offline social connectedness on adolescent mental health and well-being, and the moderating role of the social determinants of health (SDoH) were explored. Canadian adolescents (n=1,586; M_age=15.3, range 13 to 18 years; surveyed summer 2022) reported their social connectedness, psychological distress, and mental well-being. An ordinal logistic regression was performed to examine the association between social connectedness (online and offline) and dual-factor mental health. Responses to two open-ended survey questions were analyzed. Social disconnection was associated with higher odds of being in a …

Rehabilitation Interventions For Physical Capacity And Quality Of Life In Adults With Post-Covid-19 Condition: A Systematic Review And Meta-Analysis., Dimitra V Pouliopoulou, Joy C Macdermid, Emily Saunders, Sue Peters, Laura Brunton, Erin Miller, Kieran L Quinn, Tiago V Pereira, Pavlos Bobos

Physical Therapy Publications

IMPORTANCE: Current rehabilitation guidelines for patients with post-COVID-19 condition (PCC) are primarily based on expert opinions and observational data, and there is an urgent need for evidence-based rehabilitation interventions to support patients with PCC.

OBJECTIVE: To synthesize the findings of existing studies that report on physical capacity (including functional exercise capacity, muscle function, dyspnea, and respiratory function) and quality of life outcomes following rehabilitation interventions in patients with PCC.

DATA SOURCES: A systematic electronic search was performed from January 2020 until February 2023, in MEDLINE, Scopus, CINAHL, and the Clinical Trials Registry. Key terms that were used to identify potentially …

Ontario Adults' Mental Health, Wellbeing, And Prosocial Behaviour During The First 16 Months Of The Covid-19 Pandemic: A Longitudinal Study, Katie J. Shillington

Electronic Thesis and Dissertation Repository

The overall purpose of this dissertation was to provide a detailed assessment of the mental health, wellbeing, and prosocial behaviour of Ontario adults aged 30–59 (those at highest risk for losing years of healthy life due to chronic disease) during the first 16 months of the COVID-19 pandemic (April 2020–August 2021). To address this dissertation’s purpose specifically, four distinct yet thematically connected articles were written. Article 1 provides the starting point of this program of research via an overview of Ontario adults’ inter-related health behaviours (i.e., physical activity, sedentary behaviours, and dietary intake) and outcomes including, mental health, and wellbeing …

The Resilience And Socioeconomic Status Of Caregivers And School-Aged Children In The Context Of The Covid-19 Pandemic, Julia Yates

Electronic Thesis and Dissertation Repository

Introduction: The COVID-19 pandemic has challenged caregivers’ and school-aged children’s ability to adapt. Their adaptability may be due to their resilience, which socioeconomic status (SES) may impact.

Methods: Surveys were administered to 22 caregivers and 27 school-aged children (7-10 years) living in Ontario to measure their resilience and SES in the context of COVID-19. Correlations were employed to explore relationships between: (1) caregiver and child resilience; and (2) resilience and SES.

Results: Analyses found no significant relationship between caregiver and child resilience, nor resilience and SES in the context of COVID-19. Trends revealed caregivers with normal resilience had a higher …

Return To Play: Impact Of Urbanicity And Socioeconomic Status On Parents’ Attitudes Regarding Their Children's Play And Sport During The Covid-19 Pandemic, Kendall Saravanamuttoo

Electronic Thesis and Dissertation Repository

The COVID-19 pandemic has had a profound impact on the daily routines of parents and children. The primary aim of this study was to explore the influence of socioeconomic status (SES) and urbanicity on parents’ attitudes toward their children’s active play opportunities 6 months and 1.5 years into COVID-19. The secondary objective was to explore how parents’ attitudes at 6 months related to the structured and unstructured play opportunities that children returned to 1 year later, while moderating the effects of SES and urbanicity. A sample of 239 Ontario parents of children (< 12) completed two online surveys (August – December 2020; 2021). In general, parents in communities with urban features (e.g., densely populated areas), single-parents, full-time employed parents, and parents of lower-income were more hesitant to return their children to active play during the pandemic. Findings from this work highlight SES and urbanicity disparities that continue to exist during COVID-19.

Family Physicians' Responses To Personal Protective Equipment Shortages In Four Regions In Canada: A Qualitative Study., Maria Mathews, Dana Ryan, Lindsay Hedden, Julia Lukewich, Emily Gard Marshall, Shabnam Asghari, Amanda Lee Terry, Richard Buote, Leslie Meredith, Lauren Moritz, Sarah Spencer, Judith B. Brown, Erin Christian, Thomas R. Freeman, Paul S. Gill, Shannon L. Sibbald, Eric Wong

Health Studies Publications

BACKGROUND: Despite well-documented increased demands and shortages of personal protective equipment (PPE) during previous disease outbreaks, health systems in Canada were poorly prepared to meet the need for PPE during the COVID-19 pandemic. In the primary care sector, PPE shortages impacted the delivery of health services and contributed to increased workload, fear, and anxiety among primary care providers. This study examines family physicians' (FPs) response to PPE shortages during the first year of the COVID-19 pandemic to inform future pandemic planning.

METHODS: As part of a multiple case study, we conducted semi-structured qualitative interviews with FPs across four regions in …

Family Physicians' Responses To Personal Protective Equipment Shortages In Four Regions In Canada: A Qualitative Study., Maria Mathews, Dana Ryan, Lindsay Hedden, Julia Lukewich, Emily Gard Marshall, Shabnam Asghari, Amanda L. Terry Dr., Richard Buote, Leslie Meredith, Lauren Moritz, Sarah Spencer, Judith B Brown, Erin Christian, Thomas R Freeman, Paul S Gill, Shannon L Sibbald, Eric Wong

Health Studies Publications

BACKGROUND: Despite well-documented increased demands and shortages of personal protective equipment (PPE) during previous disease outbreaks, health systems in Canada were poorly prepared to meet the need for PPE during the COVID-19 pandemic. In the primary care sector, PPE shortages impacted the delivery of health services and contributed to increased workload, fear, and anxiety among primary care providers. This study examines family physicians' (FPs) response to PPE shortages during the first year of the COVID-19 pandemic to inform future pandemic planning.

METHODS: As part of a multiple case study, we conducted semi-structured qualitative interviews with FPs across four regions in …

Examining The Barriers, Facilitators And Attitudes Towards Covid-19 Vaccine And Public Health Measures For Black Communities In Canada: A Qualitative Study Protocol., Obidimma Ezezika, Bethelehem Girmay, Toluwalope Adedugbe, Isaac Jonas, Yanaminah Thullah, Chris Thompson

Health Studies Publications

INTRODUCTION: Black communities claim the highest number of cases and deaths due to COVID-19 in Canada. Generating culturally/contextually appropriate public health measures and strategies for vaccine uptake in black communities within Canada can better support the disproportionate impact of this pandemic. This study explores the barriers and enablers to public health measures limited to mask-wearing, disinfection, sanitation, social distancing and handwashing, as well as the barriers and attitudes towards COVID-19 vaccines among the black community.

METHODS AND ANALYSIS: We will use qualitative approaches informed by the widely accepted Consolidated Framework for Implementation Research (CFIR) to aid our investigation. We will …

Maid (Medical Assistance In Dying) And Meaning: An Exploration Of The Experience And Ability To Make Meaning Through Involvement In A Maid-Specific Bereavement Group, The Synergistic Potential Of Covid-19 And Maid, And The Impact Of Healthcare Providers Relationships From The Perspective Of Relational Ethics On The Legacy Of Maid-Involved Families Into Their Bereavement, Allyson Van Kessel

Electronic Thesis and Dissertation Repository

MAiD became legally accessible to Canadians with a grievous and irremediable illness in June of 2016. As I write in 2023, MAiD has been expanded to include patients who do not have a foreseeable death, with anticipated inclusion of those with mental illness as a sole underlying medical condition (MI-SUMC) in 2024. As MAiD now accounts for over 3% of all deaths annually in Canada, there is a growing impetus to explore ways by which MAiD practice can be improved and care can be extended to the family members following the death of a patient.

A hospital in southwestern Ontario …

Perspectives Of Middle Eastern Immigrant Parents Regarding Accessing Healthcare Services For Children During The Covid-19 Pandemic In London, Ontario, Sarvenaz Mehrabi

Electronic Thesis and Dissertation Repository

Background: During the COVID-19 pandemic, immigrants have been disproportionally affected and faced difficulties in accessing healthcare services. While it has been reported that the rate of pediatric healthcare utilization decreased during the COVID-19 pandemic, the reasons behind this decline are unclear. It has been suggested that immigrant children might be affected by the COVID-19 pandemic restrictions regarding accessing healthcare services. This study aims to understand the Middle Eastern immigrant parents’ perspectives regarding their access to healthcare services for their children in the London, Ontario, area during the COVID-19 pandemic.

Methods: This qualitative study was conducted with an interpretive description methodology …

Respiratory Pattern Analysis For Covid-19 Digital Screening Using Ai Techniques, Annita Tahsin Priyoti

Electronic Thesis and Dissertation Repository

Corona Virus (COVID-19) is a highly contagious respiratory disease that the World Health Organization (WHO) has declared a worldwide epidemic. This virus has spread worldwide, affecting various countries until now, causing millions of deaths globally. To tackle this public health crisis, medical professionals and researchers are working relentlessly, applying different techniques and methods. In terms of diagnosis, respiratory sound has been recognized as an indicator of one’s health condition. Our work is based on cough sound analysis. This study has included an in-depth analysis of the diagnosis of COVID-19 based on human cough sound. Based on cough audio samples from …

How Can Single Mothers Care For Themselves And Their Children During The Covid-19 Pandemic?, Lisbeth Alexandra Pino Gavidia

Electronic Thesis and Dissertation Repository

This work investigates how single mothers maintain healthy behaviours for themselves and their children as they try to meet the evolving COVID-19 public recommendations. Everyone has had to adapt to changing public health rules. Single mothers may have unique challenges as they juggle to adapt to changing family responsibilities since they do not have another person helping in the home, and help outside the home may be restricted by public health rules. My research plan addressed these questions to learn more about the experiences of single mothers during the pandemic: 1) What are the changes in family responsibilities? 2) How …

Wellness Study: Functional Visual Outcomes In Eye Disease Patients Following The Covid-19 Pandemic, Andrew Maher

Undergraduate Student Research Internships Conference

The COVID-19 pandemic has caused delays in health services and medical appointments, affecting approximately one in three Canadian adults. Elderly eye disease patients experienced delays in treatment for eye conditions including cataracts, glaucoma, and retinal diseases. The impact of these delays on functional visual outcomes and general health rating of elderly patients is not well understood. As part of the Wellness Study, we aimed to investigate the pandemic-related impacts on functional vision and general health rating in an elderly eye patient population in London, Ontario.

Compassion Fatigue In Healthcare Professionals During Covid-19: Scoping Review Protocol, Lucy Hui, Christina Oleynikov, Sheila Boamah, Anna Garnett

Undergraduate Student Research Internships Conference

The COVID-19 pandemic has presented unprecedented challenges to the healthcare system. With the sudden increase in workload, under-resourced facilities, and evolving healthcare practices, healthcare professionals are faced with a great psychological burden. Compassion is a crucial component to providing safe and quality care. However, the effects of the prolonged exposure to high-stress environments during COVID-19 on compassion fatigue remains understudied. This scoping literature review was conducted with the goal of answering two questions: (1) What research has been undertaken on compassion fatigue among healthcare providers over the course of COVID-19, and, (2) how did compassion fatigue among healthcare providers impact …

A Collaborative Approach To Caring For Refugees In The Covid-19 Pandemic, Sara Mojdehi

Undergraduate Student Research Internships Conference

With higher cases rates, it is clear that newcomer and refugee populations in Ontario have been disproportionately affected by the COVID-19 pandemic. These vulnerable populations generally work in settings that increase their risk of infection and do not offer sick leave (ICES, 2021). In addition, overcrowded and multigenerational housing make it difficult for these individuals to adhere to self-isolation guidelines. Language and cultural barriers among refugee populations have also limited their access to information about the virus, making it challenging to follow public health measures (ICES, 2021).

The increased likelihood of an outbreak in these communities manifested itself in London, …

(Re) Evaluating Critical Care Nurse Support Program(S) In A Tertiary Care Hospital: Intersecting The Art And Science Of Nursing, C. Patricia Mazzotta

The Dissertation-in-Practice at Western University

There is a growing critical care nurse staffing shortage with increases in nurse vacancy rates. Moral distress has been exacerbated by the SARS-CoV-2 (COVID-19) pandemic and, in particular, impacting critical care nurses. COVID-19 is a significant contributor to staffing shortages and continued nursing crisis. Thus, the impetus for the Problem of Practice (PoP): the lack of support to address the psychological, emotional, and spiritual distress suffered by critical care registered nurses in a tertiary care hospital in Central Ontario. To comprehend the realities of working in the intensive care units, leaders must first understand nurses’ lived experiences, narratives, and what …

The Quality Of Life Of Patients With Eye Diseases, Brian Edward Yu

Electronic Thesis and Dissertation Repository

Background: Health-related Quality of Life (HRQoL) values determined using direct elicitation methods and generic preference-based measures are important for economic evaluations of healthcare interventions. The ophthalmology clientele is vulnerable to psychological stressors in the context of the coronavirus disease 2019 (COVID-19) pandemic.

Objectives: To systematically identify and summarize the quality of life (QoL) of eye disease patients in general in North America and seniors with eye diseases during the COVID-19 pandemic.

Methods: A systematic review identified North American studies that quantified HRQoL of eye disease patients. A cross-sectional study was conducted among seniors with eye diseases and backwards stepwise regression …

Family Physician Leadership During The Covid-19 Pandemic: Roles, Functions And Key Supports., Maria Mathews, Dana Ryan, Lindsay Hedden, Julia Lukewich, Emily Gard Marshall, Judith Belle Brown, Paul S Gill, Madeleine Mckay, Eric Wong, Stephen J Wetmore, Richard Buote, Leslie Meredith, Lauren Moritz, Sarah Spencer, Maria Alexiadis, Thomas R Freeman, Aimee Letto, Bridget L Ryan, Shannon L Sibbald, Amanda Lee Terry

Health Studies Publications

PURPOSE: Strong leadership in primary care is necessary to coordinate an effective pandemic response; however, descriptions of leadership roles for family physicians are absent from previous pandemic plans. This study aims to describe the leadership roles and functions family physicians played during the COVID-19 pandemic in Canada and identify supports and barriers to formalizing these roles in future pandemic plans.

DESIGN/METHODOLOGY/APPROACH: This study conducted semi-structured qualitative interviews with family physicians across four regions in Canada as part of a multiple case study. During the interviews, participants were asked about their roles during each pandemic stage and the facilitators and barriers …

Regulation Of Mhc Ii Trafficking And Expression By Host And Viral Factors, Alex Lac

Electronic Thesis and Dissertation Repository

Antigen presentation by major histocompatibility complex class II (MHC II) to the adaptive immune system is crucial for mounting sterilizing immune responses. This central role has made antigen presentation a target for antagonism by many pathogens. Notably, infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) decrease MHC II expression in several immune cells. The mechanisms responsible for this suppression are unknown but involves either redirecting MHC II molecules away from the cell surface or inhibiting MHC II expression. To understand how pathogens manipulate intracellular MHC II trafficking, we first investigated the role of the Golgi trafficking regulator, ERC1, in …

Examining The Association Between Brain Mri Measures At 7 Tesla And Cognition Following Covid-19 Infection, Helma Heidari

Electronic Thesis and Dissertation Repository

The long-term neuropsychological, cognitive, and neurobiological effects of the severe acute respiratory syndrome (SARS-CoV-2) in survivors with milder symptoms are still poorly understood. In this thesis we evaluated cognitive and psychological changes approximately five weeks after a wide range of symptoms in COVID-19 illness and determined whether advanced diffusion magnetic resonance imaging measures within subcortical brain structures of the limbic system were related to neurological, respiratory, psychiatric, and gastric symptoms experienced during the acute phase of illness. Cognitive and neuropsychological evaluations were performed in 45 participants who experienced neurological symptoms during the acute phase of COVID-19 illness. Participants also underwent …

Automation Through Deep-Learning To Quantify Ventilation Defects In Lungs From High-Resolution Isotropic Hyperpolarized 129xe Magnetic Resonance Imaging, Tuneesh Kaur Ranota

Electronic Thesis and Dissertation Repository

Obstructive lung diseases are characterized by heterogenous ventilation. Hyperpolarized ¹²⁹Xe gas lung magnetic resonance imaging (MRI) can examine lung ventilation heterogeneity by acquiring high-resolution isotropic images. The current gold standard of semi-automated (SA) segmentation can be used to quantify non-isotropic ¹²⁹Xe lung images to generate ventilation defect percent (VDP), however, this method is not suitable for analysis of isotropic voxel ¹²⁹Xe images due to the large number of slices. Therefore, we used a fully automated deep learning-based (DL) lung algorithm to calculate VDP from isotropic images. SNR, SA and DL-based VDP were calculated, showing a strong positive …

Likely Community Transmission Of Covid-19 Infections Between Neighboring, Persistent Hotspots In Ontario, Canada, Ben C. Shirley, Eliseos J. Mucaki, Peter Rogan

Biochemistry Publications

Introduction: This study aimed to produce community-level geo-spatial mapping of confirmed COVID-19 cases in Ontario Canada in near real-time to support decision-making. This was accomplished by area-to-area geostatistical analysis, space-time integration, and spatial interpolation of COVID-19 positive individuals.
Methods: COVID-19 cases and locations were curated for geostatistical analyses from March 2020 through June 2021, corresponding to the first, second, and third waves of infections. Daily cases were aggregated according to designated forward sortation area (FSA), and postal codes (PC) in municipal regions Hamilton, Kitchener/Waterloo, London, Ottawa, Toronto, and Windsor/Essex county. Hotspots were identified with area-to-area tests including Getis-Ord Gi*, Global …

Likely Community Transmission Of Covid-19 Infections Between Neighboring, Persistent Hotspots In Ontario, Canada [Version 1; Peer Review: Awaiting Peer Review], Elisios J. Mucaki, Ben C. Shirley, Peter K. Rogan

Research Articles

This study aimed to produce community-level geo-spatial mapping of confirmed COVID-19 cases in Ontario Canada in near real-time to support decision-making. This was accomplished by area-to-area geostatistical analysis, space-time integration, and spatial interpolation of COVID-19 positive individuals.

Health Service Experiences And Preferences Of Frail Home Care Clients And Their Family And Friend Caregivers During The Covid-19 Pandemic, Lori E. Weeks, Sue Nesto, Bradley Hiebert, Grace Warner, Wendy Luciano, Kathleen Ledoux, Lorie Donelle

Nursing Publications

Objective: The COVID-19 pandemic has brought about a major upheaval in the lives of older adults and their family/friend caregivers, including those utilizing home care services. In this article, we focus on results from a qualitative component added to a pragmatic randomized controlled trial that focuses on the experiences of our study participants during COVID-19. A total of 29 participants responded to the COVID-19 related questions focused on their health services experiences and preferences from March-June 2020 including 10 home care clients and 19 family/friend caregivers in the provinces of Ontario and Nova Scotia, Canada. Results: Many participants were affected …

Placental Infarction And Intrauterine Growth Restriction Following Sars-Cov-2 Infection, Stephanie Moltner, Barbra De Vrijer, Harrison Banner

Paediatrics Publications

No abstract provided.

New Graduate Nurses’ Experiences Of Engaging In A Leadership Role In Hospital Settings During The Covid-19 Pandemic, Justine Jeanelle Ting

Electronic Thesis and Dissertation Repository

New graduate registered nurses are often expected to assume leadership roles and responsibilities quickly upon entering practice. Since the emergence of the COVID-19 pandemic, new nurses may find their leadership capabilities tested even further as the demands of leadership have been made increasingly complex in the context of an infectious disease outbreak. The purpose of this interpretive descriptive study was to explore new graduate registered nurses’ experiences of engaging in frontline leadership roles in hospital settings during the COVID-19 pandemic. In-depth interviews were conducted with 14 participants across Ontario. Content analysis revealed four main themes: nominated and necessitated into leadership …

Examining Public Health Risk Communication Via Social Media By Provincial And Local Health Authorities In Ontario During The Covid-19 Pandemic, Marc Resendes

Electronic Thesis and Dissertation Repository

Risk communication campaigns are essential during public health crises to inform the public about ways to mitigate, alleviate and manage potential risks. The purpose of this study was to describe risk communication on social media by Ontarian health authorities amid COVID-19, in addition to examining the strategies that guided their social media use. This was completed through (a) a narrative review of risk communication literature; (b) a qualitative content analysis of select health authority Twitter messaging following three major COVID-19 milestones; and (c) key informant interviews with those coordinating social media responses to COVID-19. Information giving and news updates were …

The Impact Of Interruptions In Gender-Affirming Medical Care During Covid-19 On Anxiety And Depression Among Trans And Non-Binary People In Canada: A Longitudinal Study, Sara Todorovic

Electronic Thesis and Dissertation Repository

Background. Transgender and non-binary (TGNB) populations experience disproportionally high levels of anxiety and depression; it is imperative we investigate how the COVID-19 pandemic may have impacted the mental health of TGNB communities. Methods. Among a Canadian sample of TGNB persons aged >=15 years, we used multiple linear regression to examine whether interruptions in gender-affirming care were associated with anxiety and depression, and whether that effect was modified by pre-pandemic mental health. Results. Anxiety and depression levels were high both pre-pandemic and during the pandemic. Approximately a quarter of TGNB persons experienced interruptions in hormonal care. After adjusting for confounders, there …

The Parallel Pandemic: A Systematic Review On The Effects Of The Covid-19 Pandemic On Eating Disorders And Ocd In Children And Adolescents, Nasong A. Luginaah

Undergraduate Student Research Internships Conference

In January 2021, Covid-19 had already been diagnosed in over 100 million individuals¹. Due to the high degree of infectivity, many countries all over the globe attempted to counter the virus by instituting nation-wide lockdowns. The effects of the lockdowns resulting from the Covid-19 Pandemic on the mental health of children and adolescents have drawn a lot of public health attention with many calling for an increased in the understanding of the potential effects the youth of today may have to endure. Two specific mental health illnesses have seemingly worsened are OCD and eating disorders.