Medicine and Health Sciences Commons^™

Hospital Emergency Room Visits For Heavy Menstrual Bleeding, Henry John Mead

Walden Dissertations and Doctoral Studies

Heavy menstrual bleeding (HMB) is a well-recognized health issue among women of reproductive age. The characteristics and demographics of women in the community with HMB who present at the emergency department (ED) are not well described. This research aimed to describe the cohort of women who seek treatment at the ED. The Healthcare Cost and Utilization Project 2016 National Emergency Department Sample was examined. The theory of reasoned action predicts that women who present at the ED are exhibiting health seeking behavior. From 32 million records, the inception cohort identified N = 111,555 cases. Using national estimation weights, this translates …

Hyperphosphatemia Contributes To Functional Iron Deficiency And Skeletal Muscle Wasting, Brian Anthony Czaya

All ETDs from UAB

Chronic kidney disease (CKD) is a global health threat that increases risk of death, which is credible to both impaired renal function and a multitude of CKD- associated comorbidities such as systemic inflammation, anemia and skeletal muscle dys- function. A distinctive feature of CKD is the dysregulation of mineral metabolism, where excess serum levels of phosphate (hyperphosphatemia) and of fibroblast growth factor 23 (FGF23) are not only viewed as biomarkers for disease severity but also exert deleterious effects towards various CKD-associated pathologies. Elevated levels of FGF23 can lead to the activation of FGF receptor 4 (FGFR4) in cell types that …

Screening For Iron-Deficiency Anemia In The Pediatric Population (Ages 1-17) In Gonaïves, Haiti, Cara Rose Fratianni

Doctor of Nursing Practice Final Manuscripts

Abstract

Purpose: The purpose of this pilot project is to screen for iron-deficiency anemia in pediatric patients (ages 1-17) in a primary school in Gonaïves, Haiti. Patients with anemia will be treated with oral supplemental iron for a period of four weeks according to WHO guidelines (WHO, 2011). All students will be treated empirically for helminths per WHO guidelines, unless treated elsewhere in the last six months (WHO, 2017). Nutritional status will also be assessed using MUAC according to WHO guidelines (2017).

Background Summary: Malnutrition contributes significantly to the problem of iron-deficiency anemia, with one in four children exhibiting stunting …

Kujdesi Infermieror Te Pacientët Me Anemi, Leonora Ademi

Theses and Dissertations

Qëllimi i këtij hulumtimi është që të konstatohet se sa pacientë janë të prekur nga anemia në rajonin e Gjilanit, menaxhimi i anemisë, mosha dhe gjinia më e prekur.

Nga protokolet e repartit të internos në Spitalin e Përgjithshëm të Gjilanit janë të regjistruar 359 pacientë në periudhën janar 2018 – janar 2019, prej të cilëve më të prekur janë pacientët e gjinisë femërore me 238 raste si dhe mosha më e atakuar është 65- 74 vjeç.

Disa nga këshillat infermierore për të evituar aneminë:

Përdorimi i ushqimeve me përmbajtje hekuri dhe vitaminash, përdorimi i suplimenteve për të zvogëluar mungesën …

Kujdesi Infermieror Tek Të Sëmurët Me Anemi Sideropenike, Zejnepe Zeqiri

Theses and Dissertations

Anemia paraqet uljen e numrave të eritrociteve në qarkullimin e gjakut, ulje e sasisë së gjakut në trup dhe sasi e zvogluar e hemoglobinës në eritrocite, që natyrisht shkon edhe me ulje të hematokritit.

Eritrocitet janë qeliza të gjakut që shërbejnë për transportimin e oksigjenit dhe dioksidit të karbonit në trupin e njeriut.

Anemia nuk është një sëmundje në vetvete por përshkruan një gjendje organizmi, domethënë ekzistenca e asaj sëmundje. Anemia mund të jetë sëmundje shumë e lodhshme dhe e rëndë për pacientin dhe mund të ndikojë seriozisht në jetën e pacientit.

Në punim do të diskutohet klasifikimi i anemive, …

Adult Postoperative Open-Heart Patients: Anemia And 30-Day Hospital Readmission, Lindsey Ryan

Dissertations

Background. In 2013 alone, more than 4% (3.9 million) of patients discharged from a hospital were readmitted. Anemia following a surgical procedure is associated with early hospital readmission.

Purpose/Aims. The following were specific aims of this dissertation:

• Aim 1. To develop an operational definition of the term condition-based maintenance as applied to health care and discuss the applicability and effectiveness of condition-based maintenance within health care.
• Aim 2. To identify the number of adult patients undergoing elective open-heart surgery with preoperative anemia.
• Aim 3. To examine the relationship between preoperative anemia, sociodemographics, and 30-day hospital readmission rates among postoperative open-heart …

Preoperative Anemia Management In Adult Outpatient Coronary Artery Bypass Graft Surgical Patients To Improve Treatment Of Preoperative Anemia, Katherine Mills

Doctoral Projects

The transfusion of blood products can lead to life-threatening complications after surgery. In addition, blood products are a scarce and expensive resource. Even though anemia in coronary artery bypass surgery patients is currently undertreated, research has shown that the intravenous infusion of iron products, as well as a single dose of erythropoietin-alpha prior to surgery, decreases the amount of blood products used in the perioperative setting. The goal of this pilot project was to increase the number of patients screened for anemia, and if necessary, treated prior to coronary artery bypass graft surgery.

Methods: This was a practice improvement, pilot …

Mechanisms Of Arsenic-Induced Suppression Of Early Red Blood Cell Development, Sebastian Medina

Biomedical Sciences ETDs

Anemia adversely impacts the health of more than a billion people worldwide. A strong association between anemia and arsenic exposure has been reported in epidemiological studies from multiple countries. However, the mechanistic bases for the association between arsenic exposure and anemia is not fully understood. In this study, we found an inverse association between drinking water arsenic exposures and clinical indicators of anemia (i.e., red blood cell counts and hematocrit/packet cell volumes) in a cohort of men from rural Bangladesh enrolled in the Health Effects of Arsenic Longitudinal Study.

Follow-up studies in mice, revealed that 60-day exposure to trivalent inorganic …

Iron Deficiency Anemia, Heather Weaver

Nursing Student Class Projects (Formerly MSN)

“Iron deficiency anemia (IDA) is the most common type of nutritional disorder worldwide, occurring in both developing and developed countries and affecting as many as one-fifth of the world population” (Huether & McCance, 2018, p. 934). There are many causes including bleeding (usually intestinal or menstrual), pregnancy, malnutrition, and malabsorption. Some of the signs and symptoms include fatigue, dizziness, headaches, exertional shortness of breath, cold intolerance, and paler than normal skin tones. The American Society of Hematology (2019) reports iron is important in the production of hemoglobin and maintenance of healthy cells. The topic of IDA was chosen as a …

Evaluation Of Anemia In Communities Served By Shoulder To Shoulder Global: A Cross-Sectional Study In Santo Domingo, Ecuador, Kevin Mercer

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

BACKGROUND: Shoulder to Shoulder Global (STSG) recognizes anemia as a cause of morbidity among patients in Santo Domingo, Ecuador. Little research has been done to assess targetable anemia risk factors to serve as a foundation for future pharmacotherapeutic interventions. This study sought to identify risk factors for anemia in this population.

METHODS: Data obtained from existing patient records from January 1, 2010 to August 31, 2016 included hemoglobin/hematocrit, age, sex, pregnancy status, and presenting community. Chi-square tests compared means to examine risk factors associated with anemia. Poisson regression and incidence rate ratios (IRR) were used to estimate risk factors associated …

Determinants Of Low Birth Weight In A Population-Based Sample Of Zimbabwe, Paul Nesara

Walden Dissertations and Doctoral Studies

Low birth weight (LBW) is a major public health concern globally. Despite its negative social and economic impact on the family and community at large, it has remained relatively unexplored at population level in Zimbabwe. The purpose of the study was to establish determinants of LBW using data from the 2015 Zimbabwe Demographic and Health Survey. The socioecological model was the conceptual framework for the study. A secondary analysis was conducted on 4,227 mother-infant dyads. Independent variables were duration of pregnancy, number of births within the past 5-year period, exposure to mass media, type of fuel used for cooking in …

Predictors Of Anemia Among Hiv Patients In Uganda, Catherine Nagawa

Masters Theses

HIV-related anemia is associated with increased risk of death. Prior studies suggest an inverse relationship between CD4 cell count and anemia, and a positive relationship between HIV-clinical stage and anemia. However, none have assessed the role of antiretroviral therapy (ART) treatment combinations in these relationships. Therefore, we conducted a cross-sectional study to evaluate the relationship between CD4 cell count, HIV clinical stage and anemia among 4803 Ugandan HIV-patients, and assessed the role of ART treatment combinations. We included HIV patients (> 15 years) receiving ART therapy combinations between 2010- 2015. We evaluated CD4 cell count and anemia using blood tests, …

Comparison Of Iron Supplementation And Albendazole On Anemia In Ghanaian Children, Megan M. Zitting

Theses and Dissertations

Half a billion school aged children suffer from anemia, with the majority of anemia caused by iron deficiency. Researchers have shown a strong correlation between low hemoglobin levels and presence of intestinal parasites in children with anemia. Childhood anemia has profound negative effects on physical growth, maturation, and cognitive development leading to poorer educational achievement. Using hemoglobin as a measure of anemia, this quasi-experimental study investigated impact of either iron supplementation or an antiparasitic medication on hemoglobin levels in two groups of children in a rural region of Eastern Ghana. Surprisingly, after a 6-month intervention period, hemoglobin levels in both …

Examining The Relationship Between Anemia, Cognitive Function, And Socioeconomic Status In School-Aged Ecuadorian Children, Angela Chamberlain

Theses and Dissertations

Background and Objectives: It is estimated that over 40% of children in Ecuador are anemic. Anemia in children can influence physical and cognitive development and have lasting effects on adulthood productivity and quality of life. The objectives of this study were to: (1) evaluate the relationship of anemia and cognitive function, and (2) determine the influence of demographic factors on cognitive function. Population and Setting: The sample consisted of 175 school-aged children between 5 to 11 years old attending a school in a poverty stricken area of Guayaquil, Ecuador. Methods: A descriptive correlational cross sectional design was used to study …

Hereditary Spherocytosis, Dolores Loeser

Nursing Student Class Projects (Formerly MSN)

Hereditary Spherocytosis (HS) is a hemolytic anemia where red blood cell membranes are spherical unlike common red blood cells, which are flat and round. In individuals with HS the spleen does not recognize these amorphous cells and destroys—rather filters—them them, making the individual anemic (MedlinePlus, 2013). HS is an autosomal dominant, or recessive autosomal inherited blood disease (Huq, Pietroni, Rahman & Alam, 2010) HS happens in 1 in 2,000 of the Caucasian population in or from Northern Europe (MedlinePlus, 2013). The proteins involved in HS are ankyrin-1, ά-spectrin, β-spectrin, band 3, and protein 4.2. Hyperbilirubinemia is a common symptoms in …

Is Iron Sucrose (Venofer) A Safe Treatment For People With Chronic Kidney Disease?, Kait Reid

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this study is to determine if Iron Sucrose (Venofer) is a safe treatment for people with Chronic Kidney Disease.

Identification Of Novel Allosteric Regulators Of Human Erythrocyte Pyruvate Kinase, Shilpa S. Kharalkar

Theses and Dissertations

Erythrocyte pyruvate kinase (R-PK) is a key glycolytic enzyme catalyzing the transphosphorylation of phosphoenolpyruvate (PEP) and ADP to pyruvate and ATP respectively3,4. The substrate PEP and product pyruvate of this reaction are involved in a number of energetic and biosynthetic pathways; hence a tight regulation of R-PK activity is crucial not only for glycolysis, but also for the entire cellular metabolism. Deficiency of R-PK is one of the most common enzymatic defects of RBC, and may be caused by mutations of the PK-LR (pyruvate kinase liver red blood cell) gene31, 32. Clinically, R-PK deficiency manifests itself as a chronic life-long …

Effectiveness Of Erythropoietin Therary In The Treatment Of The Anemia In Clients With End-Stage Renal Disease In Mississippi, Elizabeth Duncan

MSN Research Projects

Clients with end-stage renal disease (ESRD) often experience an associated anemia which has been attributed to an endocrine deficiency of erythropoietin. The purpose of this descriptive, retrospective study was to describe the characteristics of the effectiveness of erythropoietin (EPO) therapy on the anemia associated with ESRD. The research question generated was how effective is EPO therapy in the treatment of the anemia in clients with ESRD in Mississippi? Orem's Self-Care Model was the theoretical framework used for this study. The sample (N = 100) consisted of 55 males clients and 45 female clients from an ambulatory dialysis unit in Northeast …

Role Of Iron And Protein In The Treatment Of Hypochromic Anemia, Hodson H. Hansen

MD Theses

No abstract provided.

Pathogenesis Of Hereditary Hemolytic Jaundice, Loren L. Imes

MD Theses

No abstract provided.

Anemias Of Pregnancy, Howard H. Cowlishaw

MD Theses

No abstract provided.

Etiological Considerations Of Pernicious Anemia, Charles C. White

MD Theses

No abstract provided.

Etiology, Diagnosis And Pathology Of Hemolytic Jaundice, Clarence R. Weber

MD Theses

No abstract provided.

Treatment Of Pernicious Anemia, Leo L. Diamond

MD Theses

No abstract provided.

Hemolytic Anemia Blood Findings, Ralph T. Cunningham

MD Theses

No abstract provided.

Etiology Of Pernicious Anemia, Ernest F. Tinetti

MD Theses

No abstract provided.

Idiopathic Hypochromic Anemia, Hollis H. Brainard

MD Theses

No abstract provided.

Treatment Of Pernicious Anemia, J. M. Boomer

MD Theses

No abstract provided.

Pernicious Anemia, Particularly Its Etiology And Treatment, Beber Meyer

MD Theses

No abstract provided.

Idiopathic Aplastic Anemia, Lowell C. Barr

MD Theses

No abstract provided.