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Alzheimer's disease

Utah State University

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

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Full-Text Articles in Medicine and Health Sciences

Relationship Between Cognitive Reserve And Rate Of Decline In Alzheimer’S Disease: A Population Study, Katherine Treiber May 2010

Relationship Between Cognitive Reserve And Rate Of Decline In Alzheimer’S Disease: A Population Study, Katherine Treiber

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

According to the theory of cognitive reserve, cognitively enriching aspects of life experience (e.g., education, occupation, and leisure activity) foster the development of more efficient neural networks and cognitive strategies, enabling individuals to cope more effectively with the pathology of dementia. Using extant data from a population-based study, we examined: (1) the effect of reserve accrued through middle life on course of neuropsychological decline; and (2) the role of ongoing engagement in mentally stimulating leisure activities in rate of general cognitive and functional deterioration.

In linear mixed models, level of occupational attainment did not affect rate of cognitive or functional …


Glycemic Load And Risk Of Alzheimer's Disease: The Cache County Study On Memory, Health, And Aging, Eun Young Choi May 2008

Glycemic Load And Risk Of Alzheimer's Disease: The Cache County Study On Memory, Health, And Aging, Eun Young Choi

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Carbohydrates are a major energy source for the human body and particularly glucose is the only energy source for the brain. Thus glucose metabolism is important to maintain normal brain function. Evidence showed insulin resistance and diabetes are associated with cognitive decline and a large amount of highly processed carbohydrate intake; in other words, a high glycemic load diet, which increases blood glucose faster and insulin demand, is associated with increased risk of insulin resistance and diabetes.

Based on this premise, the hypothesis that a high glycemic load (GL) diet increases the risk of incident Alzheimer’s disease (AD) was examined …