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Relationship Between Cognitive Reserve And Rate Of Decline In Alzheimer’S Disease: A Population Study, Katherine Treiber

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

According to the theory of cognitive reserve, cognitively enriching aspects of life experience (e.g., education, occupation, and leisure activity) foster the development of more efficient neural networks and cognitive strategies, enabling individuals to cope more effectively with the pathology of dementia. Using extant data from a population-based study, we examined: (1) the effect of reserve accrued through middle life on course of neuropsychological decline; and (2) the role of ongoing engagement in mentally stimulating leisure activities in rate of general cognitive and functional deterioration.

In linear mixed models, level of occupational attainment did not affect rate of cognitive or functional …