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Unprovoked Seizures And Myoclonus In Patients With Alzheimer's Disease, Marcia L. Morris

Journal of the Minnesota Academy of Science

Although anecdotal references commonly presume that seizures eventually occur in patients affected with dementia of the Alzheimer type (DAT), no previous American study has documented the rate of new onset, unprovoked seizures in DAT patients. There are few documented cases of the occurrence of myoclonus in autopsy-proven DAT. In a series of 83 autopsy-proven DAT cases, medical records were scrutinized for the presence of any seizure or myoclonic activity. Final evaluations were made by a neurologist. Of the 83 cases, 8 had experienced one or more unprovoked seizures after the onset of DAT. Based on age-specific incidence rates from a …