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Medicine and Health Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

2022

Depression

Philadelphia College of Osteopathic Medicine

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Full-Text Articles in Medicine and Health Sciences

Is S-Adenosylmethionine (Same) An Effective Drug To Help Treat Patients With Depression?, Cassidy M. Flanigan Jan 2022

Is S-Adenosylmethionine (Same) An Effective Drug To Help Treat Patients With Depression?, Cassidy M. Flanigan

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of the selective EBM review is to determine whether or not “Is Sadenosylmethionine (SAMe) an Effective Drug to Help Treat Patients with Depression?”

Study Design: A systematic review of three randomized controlled trials (RCTs) published between 2016-2020.

Data Sources: All three RCTs were discovered using PubMed. The articles were published in English in peer-reviewed journals and selected based on applicability to the clinical question.

Outcome Measured: A reduction in depressive symptoms was the outcome measured in all three studies using the Montgomery-Asbery Depression Rating Scale (MADRS). The mean change in baseline was calculated once intervention was received. …


Do Probiotics Decrease Depressive Symptoms In Patients With Low Mood?, Kaitlyn Talt Jan 2022

Do Probiotics Decrease Depressive Symptoms In Patients With Low Mood?, Kaitlyn Talt

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review is to determine, “Do probiotics decrease depressive symptoms in patients with low mood?”

Study Design: A systematic review of three double blind, randomized control trials (RCTs) published between 2016 and 2019.

Data Sources: All three RCTs were found using PubMed and published in English in peer-reviewed journals. The articles were chosen based on their attention to patient-oriented evidence that matters (POEMS) and their relevance to the clinical question.

Outcome Measured: All three articles utilized either the Beck Depression Index (BDI) and/or the Depression Anxiety Stress Scale (DASS) to measure the severity of …