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Articles 1 - 23 of 23
Full-Text Articles in Medicine and Health Sciences
Practical Mouse Model To Investigate Therapeutics For Staphylococcus Aureus Contaminated Surgical Mesh Implants, Madison M. Collins, Brent Race, Ronald J. Messer, Chase Baune, Scott D. Kobayashi, Dan Long, Katie Williams, Aaron M. Hasenkrug, Kim Hasenkrug, Natalia Malachowa
Practical Mouse Model To Investigate Therapeutics For Staphylococcus Aureus Contaminated Surgical Mesh Implants, Madison M. Collins, Brent Race, Ronald J. Messer, Chase Baune, Scott D. Kobayashi, Dan Long, Katie Williams, Aaron M. Hasenkrug, Kim Hasenkrug, Natalia Malachowa
School of Medicine Faculty Publications
Introduction: The use of prosthetic mesh in hernia repair provides a powerful tool to increase repair longevity, decrease recurrence rates, and facilitate complex abdominal wall reconstruction. Overall infection rates with mesh are low, but for those affected there is high morbidity and economic cost. The availability of a practicable small animal model would be advantageous for the preclinical testing of prophylactics, therapeutics, and new biomaterials. To this end, we have developed a novel mouse model for implantation of methicillin-resistant Staphylococcus aureus–infected surgical mesh and provide results from antibiotic and immunotherapeutic testing. Materials and Methods: Implantation of surgical mesh between fascial …
Objective Evaluation Of Clock Face Suture Using The Objective Structured Assessment Of Technical Skill Checklist, Lucille Treil, Nicole Neumann, Nicolas Chanes, Anne Lejay, Tristan Bourcier, Jean Bismuth, Jason T. Lee, Malachi Sheahan, Anne Florence Rouby, Nabil Chakfé, John Eidt, Yannick Georg, Erica Leith Mitchell, David Rigberg, Murray Shames, Fabien Thaveau, Claudie Sheahan
Objective Evaluation Of Clock Face Suture Using The Objective Structured Assessment Of Technical Skill Checklist, Lucille Treil, Nicole Neumann, Nicolas Chanes, Anne Lejay, Tristan Bourcier, Jean Bismuth, Jason T. Lee, Malachi Sheahan, Anne Florence Rouby, Nabil Chakfé, John Eidt, Yannick Georg, Erica Leith Mitchell, David Rigberg, Murray Shames, Fabien Thaveau, Claudie Sheahan
School of Medicine Faculty Publications
Objective: Assessment of the quality of the final product (QFP) is critical in simulation training, such as the clock face suture (CFS) exercise that is used to assess trainees’ needle handling and suturing accuracy. Objective Structured Assessment of Technical Skill (OSATS) scores are the gold standard for the evaluation of trainees. The aim was to investigate variability in the use of OSATS checklists and to evaluate a semi-automatic method of suture analysis vs. OSATS scores. Methods: Details of 287 CFSs performed by trainees during Fundamentals in Vascular Surgery examinations were collected. All were rated according to a seven item OSATS …
An Algorithm To Prevent Missed Bowel Injuries In Blunt And Penetrating Abdominal Trauma Patients, Ashley Clement, Logan Gold, Lance Stuke, Patrick Greiffenstein, Jonathan Schoen, John Hunt, Alan Marr, Monique St. Romain, Alison Smith
An Algorithm To Prevent Missed Bowel Injuries In Blunt And Penetrating Abdominal Trauma Patients, Ashley Clement, Logan Gold, Lance Stuke, Patrick Greiffenstein, Jonathan Schoen, John Hunt, Alan Marr, Monique St. Romain, Alison Smith
Medical Student Research Poster Symposium
Background: Bowel injuries from trauma require immediate recognition and operative intervention. Missed bowel result in significant morbidity and mortality such as infection, enterocutaneous fistulas, additional surgeries, prolonged hospitalization, and mortality. Clinical and diagnostic expertise are limited as significant blunt bowel and/or mesenteric injuries can be evasive to detect with current imaging modalities, and physical exam findings can be unreliable. Current guidelines for the management of patients with a possible bowel injury do not offer clear direction. Objective: The objective of this study was to develop decision-making algorithms to identify patients at high risk for missed bowel injuries. Methods: A retrospective …
Local Control Of Pyoderma Gangrenosum, Cameron J. Fontenot, Mark A. Maier, Nicholas Taylor, Alison A. Smith, Frank Lau
Local Control Of Pyoderma Gangrenosum, Cameron J. Fontenot, Mark A. Maier, Nicholas Taylor, Alison A. Smith, Frank Lau
Medical Student Research Poster Symposium
Background: Pyoderma gangrenosum (PG) is a rare, non-infectious neutrophilic dermatosis that presents as painful, ulcerative, non-healing wounds. Pathergy, defined as hyperreactivity of the skin following minor trauma, is one of the hallmarks of PG. Currently, there is no consensus involving the diagnosis, treatment, and management of PG. A recent case report demonstrated that the use of a dehydrated human amnion/chorion membrane (dHACM) following surgical debridement in a single patient promoted wound healing. However, the physiologic mechanism underlying the effects of PG wound treatment with dHACM remains unknown. Objective: The objective of this study is to characterize and compare PG wounds …
Medical Therapy And Sinus Surgery For The Treatment Of Chronic Rhinosinusitis: Indications For Louisiana Medicaid, Hayden J. Guidry, Sanket Dhruva, Rita Redberg
Medical Therapy And Sinus Surgery For The Treatment Of Chronic Rhinosinusitis: Indications For Louisiana Medicaid, Hayden J. Guidry, Sanket Dhruva, Rita Redberg
Medical Student Research Poster Symposium
Background: Chronic rhinosinusitis (CRS) is common and incurs a significant human and economic cost. CRS is defined as symptomatic inflammation of the paranasal sinuses and nasal cavities lasting longer than 12 weeks. Treatments include medical therapy such as saline irrigation, nasal corticosteroids, oral antibiotics, biologics, and other agents as well as procedures such as balloon ostial dilation and functional endoscopic sinus surgery (FESS). In an analysis of Louisiana Medicaid’s expenditures for calendar year 2019, there were 1,102 distinct recipients of sinus surgery (either balloon ostial dilation or FESS) for a total of $2,382,366 in professional services expenditures. Objective: This study …
Prospective Observational Registry Study Of Myriad™ Matrix And Myriad™ Morcells In Soft Tissue Reconstruction, Tyler Hernandez, Cameron Fontenot, Cayley Leblanc, Paige Deville, Frank Lau, Alison Smith
Prospective Observational Registry Study Of Myriad™ Matrix And Myriad™ Morcells In Soft Tissue Reconstruction, Tyler Hernandez, Cameron Fontenot, Cayley Leblanc, Paige Deville, Frank Lau, Alison Smith
Medical Student Research Poster Symposium
Soft tissue reconstruction is a procedure that is fundamental to the practice of surgery. Due to the paramount importance of soft tissue repair, the need to improve this procedure through the use of modernized technologies is ever-present. Myriad Matrix is an intact extracellular matrix (ECM) that is available in a 3-layer or a 5-layer configuration. It is derived from ovine (sheep) forestomach tissue and retains the innate biological structure of the native ECM-associated macromolecules, including elastin, fibronectin, glycosaminoglycans, and laminin. When rehydrated with wound exudate or sterile saline, Myriad Matrix transforms into a malleable and compliant sheet that naturally incorporates …
Risk Of Malignancy Following Radiofrequency Ablation Of Thyroid Nodules, Peter P. Issa, M Omar, C P. Issa, Y Buti, M Hussein, M Aboueisha, A Abdelhady, M Shama, G S. Lee, E Toraih, Emad Kandil
Risk Of Malignancy Following Radiofrequency Ablation Of Thyroid Nodules, Peter P. Issa, M Omar, C P. Issa, Y Buti, M Hussein, M Aboueisha, A Abdelhady, M Shama, G S. Lee, E Toraih, Emad Kandil
Medical Student Research Poster Symposium
Radiofrequency ablation (RFA) is a safe and effective treatment of symptomatic benign thyroid nodules. However, some publications have cautioned against the use of RFA in Bethesda III, IV, and V thyroid nodules due to risk of developing follicular thyroid cancer. Unfortunately, these studies lack in statistical power due to small sample size. We aim to investigate the pathological changes following RFA of Bethesda III, IV, and V thyroid nodules. Patients treated by RFA with pre-operative and post-operative fine needle aspiration (FNA) were included. Nondiagnostic nodules were subsequently subjected to ThyGeNEXT and ThyraMIR testing. The FNA results following RFA were compared …
Solid Organ Pseudoaneurysms In Patients With High-Grade Traumatic Injuries: A Case Series, Shivani Jain, Harrison Travis, Meredyth Berard, Alexis Scheurermann, Alison A. Smith
Solid Organ Pseudoaneurysms In Patients With High-Grade Traumatic Injuries: A Case Series, Shivani Jain, Harrison Travis, Meredyth Berard, Alexis Scheurermann, Alison A. Smith
Medical Student Research Poster Symposium
Objectives: Blunt abdominal trauma affects 25% of all patients admitted with traumatic injuries. Although relatively rare (occurring in 2-10% of cases of solid organ injury), the development of solid organ (splenic, hepatic, or renal) pseudoaneurysms (PSA), particularly after initial imaging, can pose a significant threat to patients. If untreated, these PSAs may rupture and lead to lifethreatening hemorrhage. Despite this risk, the use of follow-up imaging after initial CT for blunt abdominal trauma remains controversial and has not been widely embraced. This case series shares experiences at two hospitals, a level 1 and level 2 trauma center, with 47 cases …
Neurologic Outcomes Of Vasopressor Use In Patients With Traumatic Spine Cord Injury, Zohaib Lakhani, Brock Lingle, Ina Du, Emily Noel, Alison Smith
Neurologic Outcomes Of Vasopressor Use In Patients With Traumatic Spine Cord Injury, Zohaib Lakhani, Brock Lingle, Ina Du, Emily Noel, Alison Smith
Medical Student Research Poster Symposium
The incidence of spinal cord injury is approximately 54 cases per million persons in the United States, with motor vehicle collisions and falls representing the primary etiologies. The National Spinal Cord Injury Statistical Center (NSCISC) defines traumatic spinal cord injury (TSCI) as a lesion within the spinal cord and cauda equina with any sensory or motor deficit following traumatic injury. Management of TSCI involves early spinal stabilization and immobilization, pharmacologic cord protection, and surgical cord decompression if needed. Adequate spinal cord perfusion is necessary for appropriate healing and repair of injury, as well as to prevent further ischemia. The current …
Interhospital Transfers Do Not Affect Outcomes Of Necrotizing Soft Tissue Infections, Casey Landreneau, Rachel Saravia, Sarah Stobbs, Jonathan Schoen, Alison Smith
Interhospital Transfers Do Not Affect Outcomes Of Necrotizing Soft Tissue Infections, Casey Landreneau, Rachel Saravia, Sarah Stobbs, Jonathan Schoen, Alison Smith
Medical Student Research Poster Symposium
BACKGROUND: Necrotizing soft tissue infection (NSTI) is a rapidly progressive disease with high morbidity and mortality that requires extensive care and multifaceted rehabilitation typically found at a tertiary facility. However, many patients initially present to smaller outside hospitals with less resources and require inter-hospital transfer during their treatment. OBJECTIVE: The aim of in this study was to further characterize the overall prognosis of subjects with NSTI transferred to a higher echelon of care and to determine if there is a clinical difference in outcomes based on transfer status. METHODS: We conducted a retrospective, multi-institutional review of subjects admitted for NSTI …
Impact Of Mean Arterial Blood Pressure Compliance On Neurologic Outcomein Patients With Traumatic Spinal Cord Injuries, Brock D. Lingle, Zohaib Lakhani, Emily Noel, Ina Du, Alison Smith
Impact Of Mean Arterial Blood Pressure Compliance On Neurologic Outcomein Patients With Traumatic Spinal Cord Injuries, Brock D. Lingle, Zohaib Lakhani, Emily Noel, Ina Du, Alison Smith
Medical Student Research Poster Symposium
No abstract provided.
Prehospital Tension Pneumothorax: A Retrospective Review Of Indications, Wil Plants, Elizabeth Lacy, Alison Smith
Prehospital Tension Pneumothorax: A Retrospective Review Of Indications, Wil Plants, Elizabeth Lacy, Alison Smith
Medical Student Research Poster Symposium
Introduction: Thoracic trauma can result in the development of a pneumothorax, which is defined as a collapsed lung. Tension pneumothorax is a life-threatening condition caused by the build up of pressure around the lungs leading to obstructive shock. Needle thoracostomies, which involves the insertion of a needle into the pleural cavity to release pressure, can be used to promptly relieve a tension pneumothorax. Objective: The objective of this study was to evaluate the use of needle thoracostomies in the trauma population by prehospital medical providers. Methods: A retrospective chart review of adult trauma patients with prehospital needle thoracostomies presenting to …
Incidence Of Fat Necrosis Associated With Compromised Subdermal Plexus Of Diep Flaps For Breast Reconstruction, Aran Yoo, Jonathan Richard, Hannah Doran, Daniel J. Womac, Hugo St. Hilaire, Mark Stalder
Incidence Of Fat Necrosis Associated With Compromised Subdermal Plexus Of Diep Flaps For Breast Reconstruction, Aran Yoo, Jonathan Richard, Hannah Doran, Daniel J. Womac, Hugo St. Hilaire, Mark Stalder
Medical Student Research Poster Symposium
Introduction The deep inferior epigastric perforator flap (DIEP) is a major workhorse in autologous breast reconstruction. However, despite advancements in flap optimization, fat necrosis (FN) remains a problematic complication for both the patient and the surgeon, and rates are estimated to range from 6-17.4%.1 The pathophysiology of FN implicates compromised vascular supply and drainage of the flap. Anatomic studies of the blood supply to abdominal fat revealed two sources: perforating blood vessels from a deep subcutaneous plexus and the subdermal plexus.2 In certain types of reconstruction flaps may be almost completely deepithelialized, and thus the subdermal plexus incidentally compromised. The …
Management Of Anticoagulation Therapy After Craniotomy, Kierany B. Shelvin, John M. Wilson, Sarah E. Lawhon, George A. Crabill, Ellery Hayden, Olivia Gilbert, James A. Velander
Management Of Anticoagulation Therapy After Craniotomy, Kierany B. Shelvin, John M. Wilson, Sarah E. Lawhon, George A. Crabill, Ellery Hayden, Olivia Gilbert, James A. Velander
Medical Student Research Poster Symposium
Introduction: In the in-patient setting, physicians routinely administer anticoagulation (AC) therapy to treat venous thromboembolism (VTE). However, AC therapy is often held in neurosurgical patients undergoing craniotomies due to the risk of intracranial hemorrhage (ICH) associated with this operation. In addition to ICH, these patients are at an increased risk for post-operative VTE. It is estimated that 50% of patients experience VTE post-craniotomy. Currently, there is no standard protocol for VTE therapy following craniotomy. This continues to challenge neurosurgeons when determining the most appropriate management of anticoagulation therapy after craniotomy to simultaneously mitigate the risks of ICH and VTE. Purpose: …
Enzymatic Disaggregation Is Superior To Mechanical De-Epithelialization In Preparation Of Cutis Grafts For Hernia Repair: Results Of The Cutis Ex-Vivo Graft I Study (Cute Graft I), Jeanette A. Zavala, Ian Hodgdon, John Paige, Jeff Carter, Herb A. Phelan, Michael W. Cook
Enzymatic Disaggregation Is Superior To Mechanical De-Epithelialization In Preparation Of Cutis Grafts For Hernia Repair: Results Of The Cutis Ex-Vivo Graft I Study (Cute Graft I), Jeanette A. Zavala, Ian Hodgdon, John Paige, Jeff Carter, Herb A. Phelan, Michael W. Cook
Medical Student Research Poster Symposium
Introduction Biologic or synthetic mesh reinforcement is the current standard of care for abdominal hernia repairs but remains prohibitively expensive and can increase healthcare costs by over 100,000 USD per complication. The use of autologous cutis grafts (full thickness skin grafts with the epidermis removed) are a cost-effective solution. However, the process of mechanical de-epithelialization can be physically demanding, time consuming, and result in discrepancies between patients due to differences in skin pigment, with darker pigments being easier to de-epithelialize. To facilitate this process, we proposed the use of enzymatic disaggregation. In this study, we compare the effectiveness of mechanical …
Use Of Viscoelastic Testing In Trauma Patients, Nicolas Chanes, Shyam Murali, Eric Winter, Madhu Subramanian, Allyson Hynes, Mark Seamon, Jeremy Cannon, Alison Smith
Use Of Viscoelastic Testing In Trauma Patients, Nicolas Chanes, Shyam Murali, Eric Winter, Madhu Subramanian, Allyson Hynes, Mark Seamon, Jeremy Cannon, Alison Smith
Medical Student Research Poster Symposium
Background: Coagulopathic trauma patients are at a three-fold higher risk of death compared to noncoagulopathic patients. However, identification and targeted treatment of coagulopathy is still being researched. Thromboelastography (TEG) may allow us to not only identify these patients, but also provide optimal transfusion to reverse coagulopathy. Methods: This was a secondary analysis of a multicenter retrospective review, which included adult patients receiving massive transfusion protocol. A numerical “TEG score” was calculated for each patient based on abnormalities in TEG alpha angle (<65 >degrees), clot time (>8.9 min), and clot strength (<55 >mm). Each abnormal value was assigned a point …
Severity Of Chronic Venous Insufficiency On Primary Total Knee Arthroplasty Outcomes, Tanner Reed, Eden Gallegos, Berje Shammassian, Alan Marr, Lance Stuke, Patrick Greiffenstein, Jonathan Schoen, John P. Hunt, Alison Smith
Severity Of Chronic Venous Insufficiency On Primary Total Knee Arthroplasty Outcomes, Tanner Reed, Eden Gallegos, Berje Shammassian, Alan Marr, Lance Stuke, Patrick Greiffenstein, Jonathan Schoen, John P. Hunt, Alison Smith
Medical Student Research Poster Symposium
Current screening guidelines for intoxicated trauma patients favor the routine use of cervicalspine (c-spine) CT scans. The objective of this study was to identify parameters that predispose intoxicated trauma patients to c-spine injuries in order to refine diagnostic imaging utilization. A retrospective chart review of intoxicated adult trauma patients involved in motor vehicle collisions presenting to a Level I trauma center from March 2020-September 2021 was performed. Baseline demographics, protective devices, and Injury Severity Score (ISS) were assessed in patients with c-spine fractures or nerve root damage, diagnosed by clinical examination and imaging, compared to patients without injuries. Univariate and …
Pilot Study Of Minimally Adherent Silver Dressings For Acute Surgical Wounds, Meredyth B. Berard, Frank H. Lau
Pilot Study Of Minimally Adherent Silver Dressings For Acute Surgical Wounds, Meredyth B. Berard, Frank H. Lau
School of Medicine Faculty Publications
Background and Aims: Minimally adherent silver dressings (SILVER MASD) are antimicrobial, nonirritating, provide a moist wound healing environment, and low cost. The purpose of this pilot, single-center, non-blinded randomized controlled trial was to quantify the outcomes of acute surgical wounds treated with MASD versus standard of care (SoC) dressings. Methods: Thirty-two patients with acute wounds were randomized 1:1 to be treated with MASD once weekly or SoC following surgical excision of skin and/or subcutaneous tissue between September 13, 2016 and November 28, 2017. The outcome variables included clinical infection, time to wound closure, and pain scores at dressing changes. Two …
Cholecystitis Secondary To Salmonella Typhi: A Rare Pathology With An Unreported Management Option—A Case Report And Literature Review, Michael Ghio, Angelle Billiot, Jessica A. Zagory, Mary L. Brandt
Cholecystitis Secondary To Salmonella Typhi: A Rare Pathology With An Unreported Management Option—A Case Report And Literature Review, Michael Ghio, Angelle Billiot, Jessica A. Zagory, Mary L. Brandt
School of Medicine Faculty Publications
Background: This report describes the presentation and course of treatment for one of the youngest reported cases of empyema of the gallbladder. Given the rare occurrence of this disease process, we elected to proceed with a systematic review of the literature. This is only the 7th case series discussing pediatric empyema of the gallbladder due to Salmonella typhi in the literature, and the second case ever reported in the USA. Case presentation: We report a case of a previously healthy 13-month-old girl who presented with diffuse peritonitis and equivocal imaging studies. Diagnostic laparoscopy revealed purulent peritonitis. The gallbladder was distended …
A Modular Surgical Simulator For Microlaryngoscopy Using Standard Instruments And The Carbon Dioxide Laser, Sara E. Bressler, Lacey K. Adkins, Michael E. Dunham, Rohan R. Walvekar, Jangwook P. Jung, Jorge A. Belgodere, Adam X. Bao, Lizabeth S. Breaux, Hunter C. Lee, Soheil Saneei, Austin P. Veal, John S. Carleton
A Modular Surgical Simulator For Microlaryngoscopy Using Standard Instruments And The Carbon Dioxide Laser, Sara E. Bressler, Lacey K. Adkins, Michael E. Dunham, Rohan R. Walvekar, Jangwook P. Jung, Jorge A. Belgodere, Adam X. Bao, Lizabeth S. Breaux, Hunter C. Lee, Soheil Saneei, Austin P. Veal, John S. Carleton
School of Medicine Faculty Publications
Objective: Build a microlaryngoscopy surgical simulator for endoscopic laryngeal surgery using standard microsurgical instruments and a CO2 laser. Study design: Anatomical modeling, CAD design and 3D printed manufacturing. Subjects and methods: We created a modular design for a microlaryngoscopy simulator in CAD software. Components include plastic and stainless-steel models of a standard operating laryngoscope and a cassette system for mounting porcine or synthetic models of the vocal folds. All simulator parts, including the metallic laryngoscope model, were manufactured using 3D printing technology. Tumors were simulated in porcine tissue models by injecting a soy protein-based tumor phantom. Residents and faculty in …
Pilot Phase Results Of A Prospective, Randomized Controlled Trial Of Narrowband Ultraviolet B Phototherapy In Hospitalized Covid-19 Patients, Frank H. Lau, Catherine E. Powell, Giacomo Adonecchi, Denise M. Danos, Andrew R. Dinardo, Robert J. Chugden, Peter Wolf, Carmen F. Castilla
Pilot Phase Results Of A Prospective, Randomized Controlled Trial Of Narrowband Ultraviolet B Phototherapy In Hospitalized Covid-19 Patients, Frank H. Lau, Catherine E. Powell, Giacomo Adonecchi, Denise M. Danos, Andrew R. Dinardo, Robert J. Chugden, Peter Wolf, Carmen F. Castilla
School of Medicine Faculty Publications
COVID-19 morbidity and mortality are driven by poor immune regulation. Narrowband ultraviolet B (NB-UVB) phototherapy is standard of care in a number of immune-dysregulated diseases. To assess the efficacy of NB-UVB phototherapy for improving COVID-19 outcomes in high-risk, hospitalized, we developed the Adaptive Photo-Protection Trial. This is a multi-center, prospective, double-blinded, randomized, placebo-controlled trial. The pilot phase results are reported here. Consecutive patients admitted with a positive COVID-19 PCR were screened for eligibility. Enrolled subjects were computer randomized 1:1 to NB-UVB or placebo phototherapy. Subjects were treated daily with escalating doses on 27% of their body surface area for up …
Expression Of The Preadipocyte Marker Zfp423 Is Dysregulated Between Well-Differentiated And Dedifferentiated Liposarcoma, Thanh N. Dang, Rafael P. Tiongco, Loren M. Brown, Jessica L. Taylor, John M. Lyons, Frank H. Lau, Z. Elizabeth Floyd
Expression Of The Preadipocyte Marker Zfp423 Is Dysregulated Between Well-Differentiated And Dedifferentiated Liposarcoma, Thanh N. Dang, Rafael P. Tiongco, Loren M. Brown, Jessica L. Taylor, John M. Lyons, Frank H. Lau, Z. Elizabeth Floyd
School of Medicine Faculty Publications
Background: Well-differentiated and dedifferentiated liposarcomas are rare soft tissue tumors originating in adipose tissue that share genetic abnormalities but have significantly different metastatic potential. Dedifferentiated liposarcoma (DDLPS) is highly aggressive and has an overall 5-year survival rate of 30% as compared to 90% for well-differentiated liposarcoma (WDLPS). This discrepancy may be connected to their potential to form adipocytes, where WDLPS is adipogenic but DDLPS is adipogenic-impaired. Normal adipogenesis requires Zinc Finger Protein 423 (ZFP423), a transcriptional coregulator of Perixosome Proliferator Activated Receptor gamma (PPARG2) mRNA expression that defines committed preadipocytes. Expression of ZFP423 in preadipocytes is promoted by Seven-In-Absentia Homolog …
Laser Interstitial Thermal Therapy For Posterior Fossa Lesions: A Systematic Review And Analysis Of Multi-Institutional Outcomes, Mohammadmahdi Sabahi, Stephen J. Bordes, Edinson Najera, Alireza M. Mohammadi, Gene H. Barnett, Badih Adada, Hamid Borghei-Razavi
Laser Interstitial Thermal Therapy For Posterior Fossa Lesions: A Systematic Review And Analysis Of Multi-Institutional Outcomes, Mohammadmahdi Sabahi, Stephen J. Bordes, Edinson Najera, Alireza M. Mohammadi, Gene H. Barnett, Badih Adada, Hamid Borghei-Razavi
School of Medicine Faculty Publications
Background: Laser interstitial thermal therapy (LITT) has emerged as a treatment option for deep-seated primary and metastatic brain lesions; however, hardly any data exist regarding LITT for lesions of the posterior fossa. Methods: A quantitative systematic review was performed. Article selection was performed by searching MEDLINE (using PubMed), Scopus, and Cochrane electronic bibliographic databases. Inclusion criteria were studies assessing LITT on posterior fossa tumors. Results: 16 studies comprising 150 patients (76.1% female) with a mean age of 56.47 years between 2014 and 2021 were systematically reviewed for treatment outcomes and efficacy. Morbidity and mortality data could be extracted for 131 …