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Efficacy Of Chitosan Paste As Intracanal Medication Against Enterococcus Faecalis And Candida Albicans Compared To Calcium Hydroxide, Pasika Thien-Ngern

Chulalongkorn University Theses and Dissertations (Chula ETD)

Introduction: Enterococcus faecalis and Candida albicans are frequently found in persistent endodontic infection and are resistant to calcium hydroxide (Ca(OH)2), a commonly used intracanal medication. Thus, an effective and safe antimicrobial medication against such refractory infection is necessary in endodontic retreatment, so we aimed to test the efficacy of chitosan paste against these microorganisms compared with Ca(OH)2 in root canals of extracted human teeth. Methods: Thirty-six sterilized human root samples prepared from extracted premolars and upper maxillary incisors were infected with E.faecalis for 14 days, while 32 were infected with C.albicans for 48 hours, for mature biofilm formation. The samples …