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Medicine and Health Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

2021

Epidemiology

Electronic Thesis and Dissertation Repository

Competing risks

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Characterizing Risk Factors Associated With The Recurrence Of Infective Endocarditis And Mortality Among People Who Inject Drugs, Janica A. Adams Apr 2021

Characterizing Risk Factors Associated With The Recurrence Of Infective Endocarditis And Mortality Among People Who Inject Drugs, Janica A. Adams

Electronic Thesis and Dissertation Repository

Background. The incidence of infective endocarditis is progressively rising among people who inject drugs.

Methods. A retrospective cohort study was conducted using data from electronic medical records to characterize important predictors that contribute to the recurrence of infective endocarditis and evaluate the associations of survival time and predictors of interest in the presence of competing risks among people who inject drugs. Multivariate logistic and survival regression analyses were carried out to identify factors associated with infective endocarditis recurrence and death.

Results. We identified a significant association between PICC line misuse and infective endocarditis recurrence (OR=2.62, P=0.005). In addition, survival …