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Articles 1 - 30 of 40
Full-Text Articles in Medicine and Health Sciences
Gender In The Time Of Covid-19: Evaluating National Leadership And Covid-19 Fatalities, Leah C. Windsor, Gina Yannitell Reinhardt, Alistair J. Windsor, Robert Ostergard, Susan Allen, Courtney Burns, Jarod Giger, Reed Wood
Gender In The Time Of Covid-19: Evaluating National Leadership And Covid-19 Fatalities, Leah C. Windsor, Gina Yannitell Reinhardt, Alistair J. Windsor, Robert Ostergard, Susan Allen, Courtney Burns, Jarod Giger, Reed Wood
Social Work Faculty Publications
In this paper we explore whether countries led by women have fared better during the COVID-19 pandemic than those led by men. Media and public health officials have lauded the perceived gender-related influence on policies and strategies for reducing the deleterious effects of the pandemic. We examine this proposition by analyzing COVID-19-related deaths globally across countries led by men and women. While we find some limited support for lower reported fatality rates in countries led by women, they are not statistically significant. Country cultural values offer more substantive explanation for COVID-19 outcomes. We offer several potential explanations for the pervasive …
Hips That Harm: When Medical Devices Fail Women, Sophie N. Putka
Hips That Harm: When Medical Devices Fail Women, Sophie N. Putka
Capstones
Medical devices that save the lives of thousands of Americans each year advance at a rapid pace - but some of them consistently leave women behind. When it comes to joint replacements and even heart devices, women have worse health outcomes. Behind this preventable problem is a system that overlooks women from start to finish. Female bodies are different from male bodies, but women are often underrepresented in medical trials for device approval. Women’s participation in clinical testing for devices has increased, but there’s rarely a detailed analysis of performance by sex, and even less information on women by race …
Gender Integration In Social And Behavior Change, Debora B. Freitas Lopez, Sanyukta Mathur, Haley Brightman, Kathryn Berryman, Kamden Hoffmann
Gender Integration In Social And Behavior Change, Debora B. Freitas Lopez, Sanyukta Mathur, Haley Brightman, Kathryn Berryman, Kamden Hoffmann
Poverty, Gender, and Youth
This document is a review of recent social and behavior change-focused program literature focusing on the integration of gender considerations into health and non-health social and behavior change interventions. The review revealed eight promising practices: employing a gender perspective throughout the program cycle to improve outcomes; synchronizing gender strategies to ensure inclusion of men and women, boys and girls; addressing gendered health disparities that affect service use; reducing harmful traditional practices; ensuring community involvement and accountability for promotion of gender equality; considering gender during emergency preparedness and response; accounting for intersecting gendered vulnerabilities that influence health and development outcomes; and …
Nursing Care In Patients With Corneal Inflammation, Kaltrina Azizi, Doruntina Ismaili
Nursing Care In Patients With Corneal Inflammation, Kaltrina Azizi, Doruntina Ismaili
UBT International Conference
There are two types of keratitis, the one which includes substance loss (ulcer) and the one where the inflammation process develops in deep layers without epithelium damage (keratitis stromalis or parenchimatosa).Common signs for all the types of keratitis are: cular pain that is intensified during the movement of palpebra on cornea. photophobia, it occurs from the painful contraction of the inflamed iris, decrease on sight sharpness, and watering.According to etiology, keratitis is divided in bacterial, viral, mitotic, allergic and trophic keratitis. According to this study, masculine gender is much more affected with 41 cases in total or 68.33%, then comes …
Association Of Depression And Resilience With Fertility Quality Of Life Among Patients Presenting To The Infertility Centre For Treatment In Karachi, Pakistan, Shireen Shehzad Bhamani, Nida Zahid, Wajeeha Zahid, Salima Farooq, Saima Sachwani, Marilyn Chapman, Nargis Asad
Association Of Depression And Resilience With Fertility Quality Of Life Among Patients Presenting To The Infertility Centre For Treatment In Karachi, Pakistan, Shireen Shehzad Bhamani, Nida Zahid, Wajeeha Zahid, Salima Farooq, Saima Sachwani, Marilyn Chapman, Nargis Asad
School of Nursing & Midwifery
Background: In Pakistan there is a dire need to explore the quality of life in infertile males and females and its undesirable psychological outcomes. This, study aimed to compare the quality of life (QoL) of males and females visiting an infertility centre for treatment and to assess its association with resilience, depression, and other socio-demographic factors.
Methods: An Analytical Cross-Sectional study was conducted amongst infertile males and females at the Australian Concept Infertility Medical Centre (ACIMC), Karachi, Pakistan. The non-probability (purposive) sampling strategy was used to recruit the participants. The sample size was 668. Data was analysed using STATA version …
Doing Nonbinary Gender: The Occupational Experience Of Nonbinary Persons In The Environment, Karen Mccarthy, Meghan Ballog, Maria Mayela Carranza, Katherine Lee
Doing Nonbinary Gender: The Occupational Experience Of Nonbinary Persons In The Environment, Karen Mccarthy, Meghan Ballog, Maria Mayela Carranza, Katherine Lee
Occupational Therapy | Faculty Scholarship
Understanding the effect of the environment is fundamental to grasping the occupational experiences of nonbinary individuals. Current research in occupational science addresses the occupations of the transgender population but often fails to distinguish between the binary and nonbinary experience. There is an absence of occupational science research that solely focuses on the nonbinary experience. This study focuses on nonbinary individuals and aims to illuminate the environmental factors that support or hinder occupational engagement for nonbinary individuals. Using a descriptive qualitative research design, we conducted two interviews per participant and photo-elicitation. Data analysis resulted in three themes: binary environments and safe …
Considerations For Studying Sex As A Biological Variable In Spinal Cord Injury, Andrew N. Stewart, Steven M. Maclean, Arnold J. Stromberg, Jessica P. Whelan, William M. Bailey, John C. Gensel, Melinda E. Wilson
Considerations For Studying Sex As A Biological Variable In Spinal Cord Injury, Andrew N. Stewart, Steven M. Maclean, Arnold J. Stromberg, Jessica P. Whelan, William M. Bailey, John C. Gensel, Melinda E. Wilson
Physiology Faculty Publications
In response to NIH initiatives to investigate sex as a biological variable in preclinical animal studies, researchers have increased their focus on male and female differences in neurotrauma. Inclusion of both sexes when modeling neurotrauma is leading to the identification of novel areas for therapeutic and scientific exploitation. Here, we review the organizational and activational effects of sex hormones on recovery from injury and how these changes impact the long-term health of spinal cord injury (SCI) patients. When determining how sex affects SCI it remains imperative to expand outcomes beyond locomotor recovery and consider other complications plaguing the quality of …
University Crime Alerts: Do They Contribute To Institutional Betrayal And Rape Myths?, Alexis A. Adams-Clark, Carly P. Smith, Prachi H. Bhuptani, Jennifer J. Freyd
University Crime Alerts: Do They Contribute To Institutional Betrayal And Rape Myths?, Alexis A. Adams-Clark, Carly P. Smith, Prachi H. Bhuptani, Jennifer J. Freyd
Dignity: A Journal of Analysis of Exploitation and Violence
Universities are mandated by the Clery Act (20 USC § 1092(f)) to publicize the occurrence of certain campus crimes. Many universities rely on “Crime Alert” emails to quickly and effectively communicate when a crime has occurred. However, communications of sexual crimes are often narrow (e.g., limited to stranger-perpetrated crimes) and misleading (e.g., containing safety tips that are not applicable to most types of sexual violence). The current paper presents the results of two studies that test the effects of reading crime alert emails on subsequent endorsement of rape myths and institutional betrayal. In Study 1, participants read a typical crime …
Individual Differences In Infants' Temperament Affect Face Processing, Jennifer L. Rennels, Andrea J. Kayl, Kirsty M. Kulhanek
Individual Differences In Infants' Temperament Affect Face Processing, Jennifer L. Rennels, Andrea J. Kayl, Kirsty M. Kulhanek
Psychology Faculty Research
Infants show an advantage in processing female and familiar race faces, but the effect sizes are often small, suggesting individual differences in their discrimination abilities. This research assessed whether differences in 6–10-month-olds’ temperament (surgency and orienting) predicted how they scanned individual faces varying in race and gender during familiarization and whether and how long it took them to locate the face during a visual search task. This study also examined whether infants viewing faces posing pleasant relative to neutral expressions would facilitate their discrimination of male and unfamiliar race faces. Results showed that infants’ surgency on its own or in …
Intimate Partner Violence (Ipv): Clinical And Societal Perspectives, Marudan Sivagurunathan
Intimate Partner Violence (Ipv): Clinical And Societal Perspectives, Marudan Sivagurunathan
Electronic Thesis and Dissertation Repository
Intimate Partner Violence (IPV) can have a lasting impact on survivors’ emotional, physical, and psychological wellbeing. IPV is multifaceted and can influence survivors’ interactions across various institutions, including healthcare settings. This PhD project consists of both qualitative and quantitative studies aimed at exploring the clinical and societal perspectives around IPV.
Study #1 sought to explore the discourses around male IPV drawn from a social networking site (Reddit.com). While some areas related to IPV are well researched, studies on male intimate partner violence survivors are limited. The results from study #1 show that male IPV disclosure is a complex process. While …
Diversity In Pre-Nursing Majors And Nursing Program Applicants, Christel Fehr
Diversity In Pre-Nursing Majors And Nursing Program Applicants, Christel Fehr
Dissertations
Problem: The population of the US has become increasingly ethnically diverse. This diversity has not been reflected in the nursing workforce with approximately 70% being Caucasian and 85% being female, resulting in a disparity in healthcare delivery by minorities. The purpose of this project was to perform an analysis of race, ethnicity, and gender diversity in undergraduate nursing applicants at a rural midwestern university.
Method: A retrospective review of nursing applications, enrollment reports, and graduation rates were examined for three academic years.
Results: 326 students (N=326) applied to the nursing program from Fall 2016 through Spring 2019. Of …
Comparison Of Dynamic Balance In Male And Female Collegiate Lacrosse And Soccer Athletes, Elizabeth Carter, Brandon Bartlome, Kurt Wilson
Comparison Of Dynamic Balance In Male And Female Collegiate Lacrosse And Soccer Athletes, Elizabeth Carter, Brandon Bartlome, Kurt Wilson
Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association
Please enjoy Volume 6, Issue 1 of the JSMAHS. In this issue, you will find Professional, Graduate, and Undergraduate research abstracts, and case reports.
Thank you for viewing this 6th Annual OATA Special Edition.
An Analysis Of Patients Undergoing Hip And Knee Arthroplasties In An Accountable Care Organization, Harjot Uppal
An Analysis Of Patients Undergoing Hip And Knee Arthroplasties In An Accountable Care Organization, Harjot Uppal
Honors Theses
Background. Total hip arthroplasty (THA) and total knee arthroplasty (TKA) are commonly performed procedures, with over one million executed each year in the United States (U.S.) (Steiner et al., 2012). By 2030, THA and TKA are projected to become the most frequently performed elective surgical procedures in the U.S. (Cram et al., 2012; Kurtz et al., 2009). Many of the previous studies on THA and TKA procedures have focused on women, primarily because they are at increased risks of developing knee osteoarthritis and sustaining hip fractures (Cummings et al., 1990; Hedlund et al., 1987; Hinton et al., 1995; Myers et …
Gender Integration In Social And Behavior Change: What Does It Take?, University Research Co., Breakthrough Research
Gender Integration In Social And Behavior Change: What Does It Take?, University Research Co., Breakthrough Research
Poverty, Gender, and Youth
This document pulls from a recent review of social and behavior change (SBC)-focused literature and highlights eight promising practices regarding how to integrate gender considerations in health and non-health SBC interventions. The practices are operationalized at different levels of the Socio-Ecological Model for Change and are mutually reinforcing. The purpose of this document is to share these promising practices with SBC partners to strengthen gender integration and mainstreaming efforts in SBC programming.
‘It’S Been A Huge Stress’: An In-Depth, Exploratory Study Of Vaccine Hesitant Parents In Southern California, Mika Kadono
‘It’S Been A Huge Stress’: An In-Depth, Exploratory Study Of Vaccine Hesitant Parents In Southern California, Mika Kadono
USF Tampa Graduate Theses and Dissertations
In 2015, the US experienced a widespread measles outbreak that originated at Disneyland, California and spread to six other states, Mexico, and Canada. That year, California passed Senate Bill 277 (SB 277), which eliminated the personal belief exemption for vaccinations required for school entry; California became the third state in the country to eliminate nonmedical exemptions. In 2019, Washington, Maine, and New York followed suit eliminating all nonmedical exemptions amid the largest measles outbreak in the US in 25 years. Many countries, including the US, are experiencing a rise in vaccine preventable diseases due, in part, to increasing vaccine hesitancy, …
Effect Of Gender On Intentional Learning Orientation, Sarah Anderson, Loyd Lee Glenn
Effect Of Gender On Intentional Learning Orientation, Sarah Anderson, Loyd Lee Glenn
Undergraduate Honors Theses
Knowledge of how gender affects learning is scarcely understood in the realm of nursing education. Prior studies have indicated certain learning styles are predictors of passing board examinations. Pinpointing specific learning styles could improve educational outcomes and produce thoroughly equipped nurses. Previous researchers have studied the differences in learning preferences according to gender; however, no studies have solely concentrated on gender specific learning preferences among undergraduate nursing students. Learning Interest, as well as Goal Orientation, were found to be statistically significant between genders.
The Effects Of Food Insecurity On Indigenous Women In Maine, Sara Imam
The Effects Of Food Insecurity On Indigenous Women In Maine, Sara Imam
Honors College
Indigenous women have been affected by food insecurity due to historical and continued impacts of settler-colonialism, which include the stripping of traditional gendered roles and responsibilities, environmental degradation, and poverty that limit access to traditional foods and resources. As a result, Indigenous women remain among the most vulnerable to malnourishment and hunger, as well as chronic health conditions that arise in part from colonial diets. Despite the severity of this issue in Native North America, there has been little research carried out on the topic in the state of Maine. This thesis analyzes the connections between factors underlying food insecurity …
Gender Differences In Correctional Supervisor Wellbeing, Work, And Home Demands, Emily Long
Gender Differences In Correctional Supervisor Wellbeing, Work, And Home Demands, Emily Long
Honors Scholar Theses
In recent years women’s participation in the American workforce has risen dramatically, while they still maintain the majority of the workload at home and in family life. Despite this increase in employment, women’s occupational health has been consistently underresearched and virtually no research has been conducted on female correctional workers. In this study we utilized a cross-sectional survey administered to 143 participants, both male and female, who work as correctional supervisors at the Connecticut Department of Correction. Participants responded to questions collecting information about their demographics, wellbeing, work, and home demands. Data analysis indicated that women, compared to men, did …
Movement In High School: Proportion Of Chinese Adolescents Meeting 24-Hour Movement Guidelines, Li Ying, Xihe Zhu, Justin A. Haegele, Yang Wen
Movement In High School: Proportion Of Chinese Adolescents Meeting 24-Hour Movement Guidelines, Li Ying, Xihe Zhu, Justin A. Haegele, Yang Wen
Human Movement Studies & Special Education Faculty Publications
The purposes of this study were (a) to examine the proportions of adolescents in China who partially or fully meet three 24-h movement guidelines on physical activity, screen-time, and sleep duration and (b) to examine whether there were gender differences in the proportion of boys and girls meeting these guidelines. The sample was made up of high school adolescents from an eastern province of China (N = 1338). The participants completed a self-reported survey on demographic variables and weekly health behaviors including physical activity, screen-time, and sleep duration. A frequency analysis was conducted to summarize the number of 24-h …
The Gender Gap In Alcohol Deaths Is Much Larger In Some States Than Others, Erin Bisesti
The Gender Gap In Alcohol Deaths Is Much Larger In Some States Than Others, Erin Bisesti
Population Health Research Brief Series
Alcohol-related deaths have been on the rise in the U.S. over the past several years. Men have higher rates of alcohol-related death than women, and the gender gap is largest in the western and southern regions of the U.S. This brief describes which states have the highest rates of alcohol-related death among men and women.
Exploring Gender Equity Through Occupation: A Critical Decolonizing Ethnography In Tanzania, Stephanie Huff
Exploring Gender Equity Through Occupation: A Critical Decolonizing Ethnography In Tanzania, Stephanie Huff
Electronic Thesis and Dissertation Repository
Within the discipline of occupational science, scholars of increasingly diverse geographical spaces have highlighted the necessity of diversity and epistemological expansion to enact transformative scholarship. In response, this dissertation enacted a critical decolonizing ethnographic project with 5 women from Tanzania to explore their experiences of gender inequities.
This thesis is composed of four integrated manuscripts, as well as introduction and conclusion chapters. Manuscript two examines past perspectives and approaches to research which examined gender equity and inequity in Tanzania, illuminating gaps and recommendations for future gendered research in Tanzania. Manuscript three presents an argument for the uptake of Africana Womanism …
Tracing Change In Female Genital Mutilation/Cutting Through Social Networks: An Intersectional Analysis Of The Influence Of Gender, Generation, Status, And Structural Inequality, Amadou Moreau, Bettina Shell-Duncan
Tracing Change In Female Genital Mutilation/Cutting Through Social Networks: An Intersectional Analysis Of The Influence Of Gender, Generation, Status, And Structural Inequality, Amadou Moreau, Bettina Shell-Duncan
Reproductive Health
Policies and programs designed to eliminate female genital mutilation/cutting (FGM/C) in Senegal have been implemented over several decades, but the practice has been surprisingly tenacious. Strategies for accelerating abandonment have been informed by theories of change, and social norms theory, in particular, has become a prominent framework for understanding behavior change dynamics. FGM/C is held in place by interdependent normative expectations: what one family chooses to do is linked to expectations of others and reinforced through social sanctions. Hence, a key strategy for promoting behavior change rests on coordinating change in norms and behavior among people who interact with one …
Relationship Between Sleep And Obesity Among U.S. And South Korean College Students, Jaesin Sa, Siyoung Choe, Beom-Young Cho, Jean-Philippe Chaput, Gyurin Kim, Chae-Hee Park, Joon Chung, Yoojin Choi, Beatrice Nelson, Yongkyu Kim
Relationship Between Sleep And Obesity Among U.S. And South Korean College Students, Jaesin Sa, Siyoung Choe, Beom-Young Cho, Jean-Philippe Chaput, Gyurin Kim, Chae-Hee Park, Joon Chung, Yoojin Choi, Beatrice Nelson, Yongkyu Kim
Background
Little is known about the relationship between sleep and obesity in young adults, particularly college students. This study examined the relationship between sleep (i.e., sleep duration and quality) and obesity in a large and diverse binational sample of college students.
Methods
Analyses were based on a 40-item paper survey from 2016/2017 to 2017/2018 academic years, with a 72% response rate. The samples were 1578 college students aged 18–25 years from five universities (two in the U.S. and three in South Korea). Weight and height were measured objectively; other measures (e.g., health behaviors) were self-reported. Multinomial logistic regression was used …
Prescribing Biases: Evaluating Race And Gender Biases Held By Medical Professionals, Adelaide Scenti
Prescribing Biases: Evaluating Race And Gender Biases Held By Medical Professionals, Adelaide Scenti
Sociology
Evaluating medical professionals implicit racial and gender biases compared to other professions provides a window into medical professionals’ covertly biased behaviors. I examine whether or not medical professionals, compared to other professions, are more likely to hold predisposed racial and gender biases. Analysis of 2000 to 2014 General Social Survey Data (N=4,772) found the framework of implicitly biased behavior against Black and female- identifying individuals held by medical professionals to be faulty. The results from the multivariate regression revealed the opposite of my hypothesis, regarding sexist (pro-natal) attitudes, medical professionals were less likely than other professions to exhibit sexist attitudes. …
Seen In Science: Lgbtq+ Inclusivity In Anatomy & Physiology Texts, Harshini Sirvisetty, Kat Ray King, Linda Catherine Fuselier
Seen In Science: Lgbtq+ Inclusivity In Anatomy & Physiology Texts, Harshini Sirvisetty, Kat Ray King, Linda Catherine Fuselier
Undergraduate Arts and Research Showcase
Biology is unique from other science disciplines in that concepts taught in core classes can inform our student’s understanding of sex and gender. A biology major encounters lessons on sex determination, sexual reproduction, and sex characteristics in their courses. The language used in these units matters. It is imperative that educators consider how the language, examples, and content that we use in classrooms drive (or not) inclusivity for gender- and sexuality-diverse (GSD) (aka LGBTQ+) individuals. We chose to analyze four college-level human anatomy/physiology (AP) textbooks for GSD population inclusivity. We adopted a queer theory framework to critically examine how sex, …
Tobacco Use Disparities By Sexual And Gender Minority Status Among Ucf Students., Parth N. Patel
Tobacco Use Disparities By Sexual And Gender Minority Status Among Ucf Students., Parth N. Patel
Digital Repository: Showcase of Undergraduate Research Excellence
No abstract provided.
Effect Of Sleep Deprivation And Sleep Recovery On Heart Rate And Heart Rate Variability In Males Versus Females, Abrianna Lochner Spt, Elena Crooks Pt, Dpt, Phd, Myles Gordon Finlay Ba, Julie A. Erwin Ms, Kimberly Honn Phd
Effect Of Sleep Deprivation And Sleep Recovery On Heart Rate And Heart Rate Variability In Males Versus Females, Abrianna Lochner Spt, Elena Crooks Pt, Dpt, Phd, Myles Gordon Finlay Ba, Julie A. Erwin Ms, Kimberly Honn Phd
2020 Symposium Posters
Introduction
Elevated heart rate (HR) and low HR variability (HRV) are indicators of increased sympathetic tone and cardiovascular risk. Here, we assess the effect of one night of sleep deprivation and a subsequent night of recovery sleep on HR and HRV in healthy males versus females.
Methods
Fifty-nine subjects (29.5±8.5y, n=35 female) completed a 4-day/3-night laboratory study. Subjects had a baseline sleep opportunity (22:00–08:00), followed by 38h of sleep deprivation, and a recovery sleep opportunity (22:00–08:00). EKG was monitored via Holter monitors to measure HR and the pNN50 and rMMSD variables of HRV. Time points used for analyses included 09:00–09:20 …
Gender Differences In Marijuana-Related Problems Among Those Who Self-Reported Daily Smoking And Marijuana Use, Justin Ho
Scholarship in Medicine - All Papers
In 2012, the National Survey on Drug Use and Health reported about 5.2% of its respondents using tobacco and marijuana, with strong evidence of increasing marijuana use among tobacco users.1 While smoking cigarettes has been shown to cause lung cancer,2 additional studies associate habitual marijuana smoking with abnormal airway tissue histology, impeded airway conductance,3 decreased memory, psychomotor speed, and manual dexterity.4 Cigarette smoking and marijuana use are shown to have similar withdrawal symptoms such as irritability, anxiety, and depression,2,5 meaning that this example of polysubstance dependence could become a valid public health concern, especially with …
Surfacing Contexts Of Violence In Novel Forms Of The Reproductive Justice Framework Through Lessons From Latin America: A Study Of Brutality, Migration And Bodily Autonomy And Progressive Solutions For Use In Public Health, Angelica M. Campos
CMC Senior Theses
In the last 5 years, Latin America has witnessed a tenacious wave of pañuelo verde and #NiUnaMenos activism. Sparked by increasing mortality rates associated with unsafe, clandestine abortions and femicide, the praxes and fundamental elements of these social movements have proven themselves useful not only in garnering international attention on issues relating to bodily autonomy, but in the synthesis of their respective sociopolitical solutions as well. In the United States, similar efforts have been spearheaded by the lauded reproductive justice framework, which has often been credited for centering the plight of women of color in both reproduction and social justice. …
Relationships Between Plasma Lipids Species, Gender, Risk Factors And Alzheimer’S Disease, Wei Ling Florence Lim, Kevin Huynh, Pratishtha Chatterjee, Ian Martins, Kaushala S. Jayawardana, Corey Giles, Natalie A. Mellett, Simon M. Laws, Ashley I. Bush, Christopher C. Rowe, Victor L. Villemagne, David Ames, Brian G. Drew, Colin L. Masters, Peter J. Meikle, Ralph Martins, Australian Imaging, Biomarker & Lifestyle Research Group
Relationships Between Plasma Lipids Species, Gender, Risk Factors And Alzheimer’S Disease, Wei Ling Florence Lim, Kevin Huynh, Pratishtha Chatterjee, Ian Martins, Kaushala S. Jayawardana, Corey Giles, Natalie A. Mellett, Simon M. Laws, Ashley I. Bush, Christopher C. Rowe, Victor L. Villemagne, David Ames, Brian G. Drew, Colin L. Masters, Peter J. Meikle, Ralph Martins, Australian Imaging, Biomarker & Lifestyle Research Group
Research outputs 2014 to 2021
Background:
Lipid metabolism is altered in Alzheimer’s disease (AD); however, the relationship between AD risk factors (age, APOE ɛ4, and gender) and lipid metabolism is not well defined.
Objective:
We investigated whether altered lipid metabolism associated with increased age, gender, and APOE status may contribute to the development of AD by examining these risk factors in healthy controls and also clinically diagnosed AD individuals.
Methods:
We performed plasma lipidomic profiling (582 lipid species) of the Australian Imaging, Biomarkers and Lifestyle flagship study of aging cohort (AIBL) using liquid chromatography-mass spectrometry. Linear regression and interaction analysis were used to explore …