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Full-Text Articles in Medicine and Health Sciences

Implementation And Sustainment Of A Statewide Telemedicine Diabetic Retinopathy Screening Network For Federally Designated Safety-Net Clinics, Ana Bastos De Carvalho, S. Lee Ware, Feitong Lei, Heather M. Bush, Robert Sprang, Eric B. Higgins Nov 2020

Implementation And Sustainment Of A Statewide Telemedicine Diabetic Retinopathy Screening Network For Federally Designated Safety-Net Clinics, Ana Bastos De Carvalho, S. Lee Ware, Feitong Lei, Heather M. Bush, Robert Sprang, Eric B. Higgins

Ophthalmology and Visual Science Faculty Publications

CONTEXT: Diabetic retinopathy (DR) is the leading cause of incident blindness among working-age adults in the United States. Federally designated safety-net clinics (FDSC) often serve as point-of-contact for patients least likely to receive recommended DR screenings, creating opportunity for targeted interventions to increase screening access and compliance.

STUDY DESIGN AND METHODS: With such a goal, we implemented and assessed the longitudinal performance of an FDSC-based telemedicine DR screening (TDRS) network of 22 clinical sites providing nonmydriatic fundus photography with remote interpretation and reporting. Retrospective analysis of patient encounters between February 2014 and January 2019 was performed to assess rates of …


Implications Of Long Non-Coding Rnas In The Pathogenesis Of Diabetic Retinopathy: A Novel Epigenetic Paradigm., Saumik Biswas Jul 2020

Implications Of Long Non-Coding Rnas In The Pathogenesis Of Diabetic Retinopathy: A Novel Epigenetic Paradigm., Saumik Biswas

Electronic Thesis and Dissertation Repository

With the rising incidence of diabetic retinopathy (DR), there is an urgent need for novel therapies. Presently, several altered metabolic pathways have been implicated in the pathogenesis of DR. Recent advances in genomic technologies have identified considerable epigenetic alterations that also contribute to DR progression. Long non-coding RNAs (lncRNAs; >200 nucleotides), critical regulators of gene expression, are aberrantly expressed in DR and have not been comprehensively characterized. Our microarray analyses using human retinal endothelial cells (HRECs) revealed thousands of differentially expressed lncRNAs following high glucose (HG) exposure, with profound increases in the lncRNAs MALAT1 and HOTAIR. Using multiple techniques, …


Topical Bromfenac Vs Focal Laser Photocoagulation In Treatment Of Focal Diabetic Macular Edema, Abd El Khalek Ebrahim Al Saadany, Eman A Hossam Eldin, Marwa A. Zaky, Sameh M. Elgouhary Jun 2020

Topical Bromfenac Vs Focal Laser Photocoagulation In Treatment Of Focal Diabetic Macular Edema, Abd El Khalek Ebrahim Al Saadany, Eman A Hossam Eldin, Marwa A. Zaky, Sameh M. Elgouhary

Menoufia Medical Journal

Objective The aim was to evaluate the safety and efficacy of topical bromfenac in comparison with focal laser photocoagulation in treatment of focal diabetic macular edema (DME). Background DME, a serious eye condition caused primarily by hyperglycemia, is the major cause of visual loss in the working population of developed countries. Patients and methods A total of 30 eyes from 30 diabetic patients with previously untreated focal DME were enrolled in this prospective randomized controlled study from October 2017 to October 2018. Patients with central macular thickness (CMT) less than 350 μm were included. Patients were divided into two equal …


Diabetic Retinopathy: Targeting Bigh3 To Develop Novel Molecular Therapies, Reanna Rodriguez, Anjalee Choudhury, Daniela Gonzalez, Cristian Mercado, Andrew Tsin May 2020

Diabetic Retinopathy: Targeting Bigh3 To Develop Novel Molecular Therapies, Reanna Rodriguez, Anjalee Choudhury, Daniela Gonzalez, Cristian Mercado, Andrew Tsin

School of Medicine Publications and Presentations

Diabetic retinopathy (DR) is a complication of diabetes due to damage of blood vessels in the retina. Aside from being a major cause of blindness in the world, DR also has a significant impact on quality of life. Although there are methods to delay the progression of DR, there are no existing therapeutic regimens for early intervention. Thus, it is critical to develop cost-effective therapies towards preventing DR development.


Improving Assessment, Documentation, And Ordering Of Diabetic Retinopathy Screenings In A Primary Care Clinic, Lauren N. Motto Jan 2020

Improving Assessment, Documentation, And Ordering Of Diabetic Retinopathy Screenings In A Primary Care Clinic, Lauren N. Motto

DNP Projects

Abstract

BACKGROUND: Diabetes mellitus (DM) is the leading cause of new blindness in American adults. As the number of people with type 2 diabetes continues to increase, the total number of people affected by diabetic retinopathy (DR) will continue to rise. Improved access to screening for DR, followed by treatment, if necessary, can reduce the progression to vision loss. Despite national recommendations, less than half of Americans with DM complete annual diabetic retinopathy screenings (DRS).

PURPOSE: The purpose of this project was to improve assessment, education, documentation, and ordering of DRS for patients with a diagnosis of type 1 and/or …


Thrombotic Microangiopathy And Acute Kidney Injury Induced After Intravitreal Injection Of Vascular Endothelial Growth Factor Inhibitors Vegf Blockade-Related Tma After Intravitreal Use, R. M. Hanna, N. Tran, S. S. Patel, J. Hou, K. D. Jhaveri, R. Parikh, U. Selamet, L. Ghobry, V. Bijol, I. B. Kurtz, +6 Additional Authors Jan 2020

Thrombotic Microangiopathy And Acute Kidney Injury Induced After Intravitreal Injection Of Vascular Endothelial Growth Factor Inhibitors Vegf Blockade-Related Tma After Intravitreal Use, R. M. Hanna, N. Tran, S. S. Patel, J. Hou, K. D. Jhaveri, R. Parikh, U. Selamet, L. Ghobry, V. Bijol, I. B. Kurtz, +6 Additional Authors

Journal Articles

No abstract provided.


Eye Screening In U.S. Adults With Diabetes: Examination Of Trends, Racial And Ethnic Differences, And Contribution Of Medicaid Expansion, Meps 2010-2017, Karon Lewis Jan 2020

Eye Screening In U.S. Adults With Diabetes: Examination Of Trends, Racial And Ethnic Differences, And Contribution Of Medicaid Expansion, Meps 2010-2017, Karon Lewis

Electronic Theses and Dissertations

Diabetic retinopathy (DR) is a prevalent cause of vision impairment and blindness among adults in the United States. Early diagnosis of DR through dilated eye examinations can reduce the risk of vision impairment or loss. Differences in eye examination rates by race and ethnicity have been suggested by prior studies emphasizing importance of increasing insurance coverage and access to care among minority populations. The Affordable Care Act aimed to expand health insurance coverage and improve access to care. This study examined trends overall and by race and ethnicity in eye examination rates and the contribution of Medicaid expansion on changes …


Evaluating Knowledge And Educating Patients About Diabetic Retinopathy Screening In Washington County, Vt, Delaney Curran Jan 2020

Evaluating Knowledge And Educating Patients About Diabetic Retinopathy Screening In Washington County, Vt, Delaney Curran

Family Medicine Clerkship Student Projects

No abstract provided.


Evaluating Knowledge And Educating Patients About Diabetic Retinopathy Screening In Washington County, Vt, Delaney Curran Jan 2020

Evaluating Knowledge And Educating Patients About Diabetic Retinopathy Screening In Washington County, Vt, Delaney Curran

Family Medicine Clerkship Student Projects

Diabetic retinopathy (DR) is a leading cause of blindness in adults. Early detection and subsequent treatment of DR has been shown to be effective at saving vision and medical costs. However, adherence to annual dilated eye exams is relatively poor among people with diabetes. This project in Waterbury, VT aimed to identify patients' potential knowledge gaps about the connection between diabetes and eye disease, educate patients about DR with a 2 min educational video in the primary care office, and then assess their level of interest in getting an eye exam after watching the video.