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Full-Text Articles in Medicine and Health Sciences
Accuracy Of Multiparametric Magnetic Resonance Imaging To Detect Significant Prostate Cancer And Index Lesion Location, Hariette Goldman, Neha Singh, Catherine Harding, Joe Mcgirr, Alexa Seal, Ian Duncan, Steven Sowter
Accuracy Of Multiparametric Magnetic Resonance Imaging To Detect Significant Prostate Cancer And Index Lesion Location, Hariette Goldman, Neha Singh, Catherine Harding, Joe Mcgirr, Alexa Seal, Ian Duncan, Steven Sowter
Medical Papers and Journal Articles
Background: Multiparametric magnetic resonance imaging (mpMRI) of the prostate appears to improve prostate cancer detection, but studies comparing mpMRI to histopathology at the time of radical prostatectomy (RP) are lacking. This retrospective study determined the accuracy of mpMRI predicting Gleason score and index lesion location at the time of RP, the current gold standard for diagnosis.
Methods: Between April 2013 and April 2016, a database of all men aged more than 40 years who underwent RP after positive transrectal ultrasound biopsy by an experienced urological surgeon was collated at a single regional centre. This was cross‐referenced with a database of …
Added Value Of Second Biopsy Target In Screen-Detected Widespread Suspicious Breast Calcifications, Nathalie M. Falkner, Dana A. Hince, Gareth Porter, Ben Dessauvagie, Sanjay Jeganathan, Max Bulsara, Glen Lo
Added Value Of Second Biopsy Target In Screen-Detected Widespread Suspicious Breast Calcifications, Nathalie M. Falkner, Dana A. Hince, Gareth Porter, Ben Dessauvagie, Sanjay Jeganathan, Max Bulsara, Glen Lo
Health Sciences Papers and Journal Articles
Introduction: There is controversy on the optimal work‐up of screen‐detected widespread breast calcifications: whether to biopsy a single target or multiple targets. This study evaluates agreement between multiple biopsy targets within the same screen‐detected widespread (≥25 mm) breast calcification to determine if the second biopsy adds value.
Methods: Retrospective observational study of women screened in a statewide general population risk breast cancer mammographic screening program from 2009 to 2016. Screening episodes recalled for widespread calcifications where further views indicated biopsy, and two or more separate target areas were sampled within the same lesion were included. Percentage agreement and Cohen's Kappa …
Intraoperative Detection Of Blood Vessels With An Imaging Needle During Neurosurgery In Humans, Hari Ramakonar, Bryden C. Quirk, Rodney W. Kirk, Jiawen Li, Angela Jacques, Christopher R.P Lind, Robert A. Mclaughlin
Intraoperative Detection Of Blood Vessels With An Imaging Needle During Neurosurgery In Humans, Hari Ramakonar, Bryden C. Quirk, Rodney W. Kirk, Jiawen Li, Angela Jacques, Christopher R.P Lind, Robert A. Mclaughlin
Health Sciences Papers and Journal Articles
Intracranial hemorrhage can be a devastating complication associated with needle biopsies of the brain. Hemorrhage can occur to vessels located adjacent to the biopsy needle as tissue is aspirated into the needle and removed. No intraoperative technology exists to reliably identify blood vessels that are at risk of damage. To address this problem, we developed an “imaging needle” that can visualize nearby blood vessels in real time. The imaging needle contains a miniaturized optical coherence tomography probe that allows differentiation of blood flow and tissue. In 11 patients, we were able to intraoperatively detect blood vessels (diameter, >500 μm) with …