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Full-Text Articles in Medicine and Health Sciences
Correction To: Hif Prolyl Hydroxylase Inhibition Protects Skeletal Muscle From Eccentric Contraction Induced Injury, Andrew N. Billin, Samuel E. Honeycutt, Alan V. Mcdougal, Jaclyn P. Kerr, Zhe Chen, Johannes M. Freudenberg, Deepak K. Rajpal, Guizhen Luo, Henning Fritz Kramer, Robert S. Geske, Frank Fang, Bert Yao, Richard V. Clark, John Lepore, Alex Cobitz, Ram Miller, Kazunori Nosaka, Aaron C. Hinken, Alan J. Russell
Correction To: Hif Prolyl Hydroxylase Inhibition Protects Skeletal Muscle From Eccentric Contraction Induced Injury, Andrew N. Billin, Samuel E. Honeycutt, Alan V. Mcdougal, Jaclyn P. Kerr, Zhe Chen, Johannes M. Freudenberg, Deepak K. Rajpal, Guizhen Luo, Henning Fritz Kramer, Robert S. Geske, Frank Fang, Bert Yao, Richard V. Clark, John Lepore, Alex Cobitz, Ram Miller, Kazunori Nosaka, Aaron C. Hinken, Alan J. Russell
Research outputs 2014 to 2021
Following publication of the original article [1], the authors flagged that there is a discrepancy with the Availability of data and materials statement on page 12 of the article.
Hif Prolyl Hydroxylase Inhibition Protects Skeletal Muscle From Eccentric Contraction-Induced Injury, Andrew N Billin, Samuel E Honeycutt, Alan V Mcdougal, Jaclyn P Kerr, Zhe Chen, Johannes M Freudenberg, Deepak K Rajpal, Guizhen Luo, Henning Fritz Kramer, Robert S Geske, Frank Fang, Bert Yao, Richard V Clark, John Lepore, Alex Cobitz, Ram Miller, Kazunori Nosaka, Aaron C Hinken, Alan J Russell
Hif Prolyl Hydroxylase Inhibition Protects Skeletal Muscle From Eccentric Contraction-Induced Injury, Andrew N Billin, Samuel E Honeycutt, Alan V Mcdougal, Jaclyn P Kerr, Zhe Chen, Johannes M Freudenberg, Deepak K Rajpal, Guizhen Luo, Henning Fritz Kramer, Robert S Geske, Frank Fang, Bert Yao, Richard V Clark, John Lepore, Alex Cobitz, Ram Miller, Kazunori Nosaka, Aaron C Hinken, Alan J Russell
Research outputs 2014 to 2021
BACKGROUND: In muscular dystrophy and old age, skeletal muscle repair is compromised leading to fibrosis and fatty tissue accumulation. Therefore, therapies that protect skeletal muscle or enhance repair would be valuable medical treatments. Hypoxia-inducible factors (HIFs) regulate gene transcription under conditions of low oxygen, and HIF target genes EPO and VEGF have been associated with muscle protection and repair. We tested the importance of HIF activation following skeletal muscle injury, in both a murine model and human volunteers, using prolyl hydroxylase inhibitors that stabilize and activate HIF.
METHODS: Using a mouse eccentric limb injury model, we characterized the protective effects …
Cognitive Impairment And Risk Of All-Cause And Cardiovascular Disease Mortality Over 20-Year Follow-Up: Results From The Blsa, Ji An, Haibin Li, Zhe Tang, Deqiang Zheng, Jin Guo, Yue Liu, Wei Feng, Xia Li, Anxin Wang, Xiangtong Liu, Lixin Tao, Chengbei Hou, Feng Zhang, Xinghua Yang, Qi Gao, Wei Wang, Xiuhua Guo, Yanxia Luo
Cognitive Impairment And Risk Of All-Cause And Cardiovascular Disease Mortality Over 20-Year Follow-Up: Results From The Blsa, Ji An, Haibin Li, Zhe Tang, Deqiang Zheng, Jin Guo, Yue Liu, Wei Feng, Xia Li, Anxin Wang, Xiangtong Liu, Lixin Tao, Chengbei Hou, Feng Zhang, Xinghua Yang, Qi Gao, Wei Wang, Xiuhua Guo, Yanxia Luo
Research outputs 2014 to 2021
Background-Cognitive impairment may increase the risk of all-cause and cardiovascular disease (CVD) mortality. This study examined the association between cognitive function and risk of all-cause and CVD mortality among the elderly in Beijing, China. Methods and Results-A total of 1996 participants aged ≥55 years at baseline were enrolled from the BLSA (Beijing Longitudinal Study of Aging). Cognitive function was assessed using the Mini-Mental State Examination (MMSE), and participants were categorized as: