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Neuronal Correlates For Neuroendocrine Habituation To Repeated Stress, Sara Matovic Dec 2017

Neuronal Correlates For Neuroendocrine Habituation To Repeated Stress, Sara Matovic

Electronic Thesis and Dissertation Repository

One way that the body actively responds to an impending stressor is by increasing systemic glucocorticoids through the activation of the hypothalamic-pituitary-adrenal (HPA) axis. While it is essential for short-term adaptation to stress, the sustained activation of the HPA axis during chronic stress can be detrimental and is linked to stress-related psychiatric conditions such as anxiety and depression. Therefore, it is important that the HPA axis adapts, or habituates, during chronic stress to minimize the negative consequences. Corticotropin releasing hormone (CRH) neurons in the paraventricular nucleus of the hypothalamus (PVN) function to assimilate incoming information from the stress circuitry and …


Resiliency In The Operating Room: Exploring Trainee Stress During Surgery And The Role Of Individual Resilience, Richard Ng Jul 2017

Resiliency In The Operating Room: Exploring Trainee Stress During Surgery And The Role Of Individual Resilience, Richard Ng

Electronic Thesis and Dissertation Repository

Surgical trainees experience significant intraoperative stress, which can negatively impact performance and learning. Psychological resilience suggests why some individuals excel despite severe stress. This study explores the relationship between trainee resilience and intraoperative stress. A novel instrument was developed to assess Surgical TRainee Experiences of StresS in the Operating Room (STRESSOR). Focus groups and a literature review identified eight domains of intraoperative stress. STRESSOR was used in a survey of orthopaedic residents in Canada and surgical trainees at Western University. Resiliency was assessed using the 10-item Connor-Davidson Resiliency Scale. 171 responses were received for a 38 percent response rate. The …