Medicine and Health Sciences Commons^™

The Engineering Of A Microscale Niche To Test A Novel Anti-Cancer Agent, Dominic M. Halsmer, William Ranahan, Alexander C. Mills

Christian Engineering Conference

Cutting-edge biomedical research often relies on innovative tools from the field of engineering. Some of these tools are designed to investigate or probe a niche, analyzing its characteristics and affordances. Other devices are engineered to create a niche in which a specific, unique interaction can take place, while the outcomes are carefully monitored. This paper will focus of the latter and, more specifically, the production of a niche for inducing promising interaction between cancer cells and certain types of fungi. Preliminary research suggests that when maintained in close proximity to breast cancer cells, mushroom mycelia secrete compounds which trigger the …

The Science Of Singing: A Voice Lesson From Anatomy And Physiology, Gracie Bennett

The Research and Scholarship Symposium (2013-2019)

The voice is the oldest instrument in existence. Throughout its history, there have been many vocal performances practices. The purpose of my research is to show the correlation between modern vocal practices and the current medical technology available to help us understand the physiology of the voice. I am studying and analyzing the vocal performance and pedagogical practices from the early church to present day. I want to know why these vocal strategies have changed over time. There have been several different schools of thinking in regards to vocal practices. From the Italian style bel canto singing that was widely …

Patients’ Perceptions Of Pharmacist Intervention Through Pre-Screened Medication Therapy Management Service, Danielle E. Baker, Colin J. Behm, Bryan Feldmann, Jeremy Flikkema, Thaddeus T. Franz

The Research and Scholarship Symposium (2013-2019)

Background: The continued challenge of time commitment in a community pharmacy setting is reported by pharmacists as the single largest setback in providing quality patient care. Additionally, when efforts are made by pharmacists to intervene on a patient’s therapy through medication therapy management (MTM), patient “no shows” further challenge an already busy community pharmacy world. Many studies show the value of a pharmacist-patient relationship. However, continued barriers prevent the value of this relationship to take full effect. While numerous methods of comprehensive medication review take place, the issue of establishing a model that best suits the needs of community pharmacy …

The Effectiveness Of Cognitive Behavioral Therapy On Management Of Symptoms In Rheumatoid Arthritis Patients, Miriam J. Morris, Bernadette F. Rowe, Jessica L. Stauf

The Research and Scholarship Symposium (2013-2019)

Objectives: To carry out a systematic review of literature examining the effectiveness of cognitive behavioral therapy (CBT) alongside pharmacological treatment of rheumatoid arthritis (RA) symptoms compared to pharmacological treatments (standard care) without CBT.

Methods: The Iowa Model of Evidence-Based Practice to Promote Quality Care was used as the theoretical framework for this review of literature. Databases utilized: CINAHL, OneSearch, PubMed, and MedLine. The inclusion criteria for this search were: CBT as an intervention, articles published within 2006-2016, and English full text articles.

Exclusion criteria were: participants less than 18 years of age, interventions other than CBT, or any other type …

E,E-Farnesol Inhibits Swarming Motility In Burkholderia Cepacia Through Rhamnolipid Production, Stephanie E. Nicholls, Alayna N. Sanderson, Andrea P. Schwartz, Lauren E. Ward, Jessica N. Weisensee, Molly Yandrofski, Tracy L. Collins

The Research and Scholarship Symposium (2013-2019)

Burkholderia cepacia and Candida albicans both exhibit cell-to-cell communication through the use of quorum-sensing molecules (QSM) known as autoinducers. E,E-farnesol is a QSM produced by C. albicans which regulates its conversion from yeast to mycelium. Because there is a positive correlation between the presence of B. cepacia and C. albicans in the lungs of individuals with cystic fibrosis (CF), we examined whether E,E-farnesol had an effect on swarming motility in B. cepacia. Swarming motility was inhibited when B. cepacia was exposed to 250 µM of E,E-farnesol. In addition, there was a 26.8% decrease in rhamnolipid production when cells were grown …

2017 Symposium Overview, Cedarville University

The Research and Scholarship Symposium (2013-2019)

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Employing “Fdalabel” Database To Extract Pharmacogenomics Information From Fda Drug Labeling To Advance The Study Of Precision Medicine, Ryley B. Uber, Hong Fang, Zhichao Liu, Joshua Xu, Shraddha Thakkar, Shashi Amur, Padmaja Mummaneni, Minjun Chen, Baitang Ning, Steve Harris, Guangxu Zhou, Leihong Wu, Paul Howard, Weida Tong

The Research and Scholarship Symposium (2013-2019)

Pharmacogenomics (PGx) focuses on how genomics and genetic variants (inherited and acquired) affect drug response. A better understanding of the association between genetic markers and individual phenotypes may improve therapy by enhancing drug efficacy, safety, and advance precision medicine. The FDALabel database (https://rm2.scinet.fda.gov/druglabel/#simsearch-0) was developed from the FDA's Structured Product Labeling (SPL) repository to allow users to perform full-text and customizable searches of the labeling section {e.g. Boxed Warning, Warning and Precautions, Adverse Reaction (AR) sections}. In this study, 48 known biomarkers were used to query PGx relevant contents from the FDALabel database, including Indication, Clinical Pharmacology, Clinical Studies, and …

Relationship Quality Of Siblings Attending The Same University, Ashley M. Belles

The Research and Scholarship Symposium (2013-2019)

This phenomenological qualitative study explores the relationship quality of siblings who both attend Cedarville University. This study seeks to identify commonalities and key components to close sibling relationships. The desire to attend the same school, or remain close to a sibling was explored, as well. Questions specifically focused on family life growing up, and current family life, while attending Cedarville University. These questions were designed to gain background information, while also gaining insight to current relationship quality and conflict. Some themes that have emerged are similarities in sibling roles based on birth order, and influencing each other in making morally …

Developmental Results Of Military Kids’ Upbringing: A Qualitative Analysis, Michael W. Firmin, Taylor E. Hobbs, Aubrey Gillette, Hannah Grammer

The Research and Scholarship Symposium (2013-2019)

In the present qualitative study, researchers focused on the similarities among college-aged military kids due to similar upbringings and shared experiences. The study was conducted through semi-structured interviews in which participants were asked to draw conclusions between past experiences and present attitudes. Researchers found major themes during the interviews and the themes of military pride, respect, and acculturation are the focus of the current presentation.

The Effects Of Square-Stepping Exercise On Risk Of Falling And Balance In Senior Adults, Grace A. Miorelli, Michaela Nelson, Elizabeth A. Sled, Benjamin T. Massa, Mackenzi J. Clemens, Hope E. Mccoll, April D. Crommett

The Research and Scholarship Symposium (2013-2019)

As people age, their body systems gradually deteriorate. Muscle function and the vestibular system slowly deteriorate leading to lower body instability. Older adults who struggle with dizziness and imbalance are more prone to falling. Dizziness and imbalance cause falls, and falls are the leading cause of hospitalization and accidental death in older adults (Shinichi & Tatsuya, 2015). It is possible to prevent and reduce the risk of falls through balance training. It is crucial that older adults take the steps needed to improve their balance and therefore reduce their risk of falling. PURPOSE: To evaluate the effect of a 10-week …

Correlation Study: Student Success In Biochemistry As A Prerequisite For Integrated Pharmacology And Medicinal Chemistry, April Filter, Stacy Lin, Sydney Schultz, Rachel Anderson, Tori Twinem, Denise S. Simpson, Melissa J. Beck

The Research and Scholarship Symposium (2013-2019)

Background

A rise in new schools of pharmacy has led to implementation of new curriculums. Pharmacy schools must adhere to standards set by the Accreditation Council of Pharmacy Education in order to provide knowledge of foundational sciences and prepare pharmacy students for the future. Prerequisites are typically foundational science courses taken early in the program so that students have the knowledge necessary to be excellent pharmacists. Within the Cedarville University School of Pharmacy, Biochemistry is a prerequisite course for Integrated Medicinal Chemistry and Pharmacology (PCoMedChem).

Objectives

The goal of this study is to determine if Biochemistry should remain a prerequisite …

The Effect Of Photoactivated Tmp On Burkholderia Cepacia Biofilms, Reyna G. Osorio, Chandra N. Swiech, Tracy L. Collins

The Research and Scholarship Symposium (2013-2019)

Burkholderia cepacia is an opportunistic pathogen that causes infections in immunocompromised individuals such as cystic fibrosis patients. B. cepacia infections are typically characterized by the formation of complex communities of cells known as biofilms. Because B. cepacia biofilms are difficult to eradicate using antibiotics, it is important to pursue alternative treatment methods. Photodynamic therapy (PDT) is a type of therapy that uses light, a photosensitizer, and oxygen to elicit cell death through the production of reactive oxygen species. PDT has been shown in previous studies to be successful in killing both Pseudomonas aeruginosa and Staphylococcus aureus. In this study, we …

Stress And Sleep Quality: Mediating Effects Of Social Support, Felisha L. Younkin, Elizabeth A. Axtell, Chelsea R. Anderton

The Research and Scholarship Symposium (2013-2019)

Stress is defined as the “nonspecific response of the body to any demand made upon it” (Kohn & Frazer, 1986). Stress is among the top five threats to academic performance among college students (Pettit & DeBarr, 2011). The purpose of the study was to investigate whether stress affects perceived sleep quality, as mediated by social support, and to determine whether stress levels vary based on academic major. Using ANOVA in SPSS 24, we tested three hypotheses: stress and sleep quality are negatively correlated, social support mediates the relationship between stress and sleep quality, and stress levels will vary by academic …