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Full-Text Articles in Medicine and Health Sciences
Renoprotective Effects Of Megadose Vitamin C On Cisplatin-Induced Kidney Injury, Supa Sithanukul, Chollada Buranakarl, Chutamas Benjanirut, Anudep Rungsipipat
Renoprotective Effects Of Megadose Vitamin C On Cisplatin-Induced Kidney Injury, Supa Sithanukul, Chollada Buranakarl, Chutamas Benjanirut, Anudep Rungsipipat
The Thai Journal of Veterinary Medicine
Cisplatin (CDDP)-induced nephrotoxicity is mediated via oxidative stress and may be alleviated using antioxidant activity. Although megadose of vitamin C may cause oxalate nephropathy and apoptosis, the antioxidant effect of vitamin C may be beneficial when given along with CDDP. The objective of this study was to investigate the renoprotective effects of megadose vitamin C on rats receiving CDDP. Rats were divided into 4 groups: group 1, control rats (CONT); group 2, vitamin C-treated rats (VIT C); group 3, CDDP-treated rats (CDDP) and group 4, CDDP + vitamin C-treated rats (CDDP + VIT C). Vitamin C (1000 mg/kg) was given …
Cisplatin Intralesional Chemotherapy Of Recurrence Schwannoma In Horse: A Case Report, Rungrueang Yodsheewan, Kanittha Phetudomsinsuk
Cisplatin Intralesional Chemotherapy Of Recurrence Schwannoma In Horse: A Case Report, Rungrueang Yodsheewan, Kanittha Phetudomsinsuk
The Thai Journal of Veterinary Medicine
A 7-year-old crossbred stallion had multiple solitary cutaneous masses at the right infraorbital area which were recurrent for two months. The biggest mass size was 5 x 7 x 1 cm3 and had superficial bleeding. This case was diagnosed as peripheral nerve sheath tumors based on cytological and histological examination which showed numerous spindle cells with cancerous characteristics, cell patterns of the tumor were interlacing bundle and a whirl. Most areas showed tense palisading nuclei of tumor cells (Verocay bodies) known as Antoni A area. The rest showed loose paucicellular tissue known as Antoni B area. Within histologic sections, the …