Medicine and Health Sciences Commons^™

The Precarious Health Of Young Mexican American Men In South Texas, Cameron County Hispanic Cohort, 2004–2015, Gordon P. Watt, Kristina Vatcheva, Derek M. Griffith, Belinda M. Reininger, Laura Beretta, Michael Fallon, Joseph B. Mccormick, Susan P. Fisher-Hoch

School of Mathematical and Statistical Sciences Faculty Publications and Presentations

Introduction

Hispanic men have higher rates of illness and death from various chronic conditions than do non-Hispanic men. We aimed to characterize the health of Mexican American men living on the US–Mexico border in South Texas and elucidate indications of chronic disease in young men.

Methods

We sampled all male participants from the Cameron County Hispanic Cohort, an ongoing population-based cohort of Mexican Americans in Brownsville, Texas. We calculated descriptive statistics and stratified the sample into 3 age groups to estimate the prevalence of sociodemographic, behavioral, and clinical factors by age group and evaluated differences between age groups.

Results

Obesity …

A Review On The Respiratory System Toxicity Of Carbon Nanoparticles, Maricica Pacurari, Kristine L. Lowe, Paul B. Tchounwou, Ramzi Kafoury

Biology Faculty Publications and Presentations

The respiratory system represents the main gateway for nanoparticles’ entry into the human body. Although there is a myriad of engineered nanoparticles, carbon nanoparticles/nanotubes (CNPs/CNTs) have received much attention mainly due to their light weight, very high surface area, durability, and their diverse applications. Since their discovery and manufacture over two decades ago, much has been learned about nanoparticles’ interactions with diverse biological system models. In particular, the respiratory system has been of great interest because various natural and man-made fibrous particles are known to be responsible for chronic and debilitating lung diseases. In this review, we present up-to-date the …

Cirrhosis And Advanced Fibrosis In Hispanics In Texas: The Dominant Contribution Of Central Obesity, Jingjing Jiao, Gordon P. Watt, Minjae Lee, Mohammad H. Rahbar, Kristina Vatcheva, Jen-Jung Pan, Joseph B. Mccormick, Susan P. Fisher-Hoch, Michael Fallon, Laura Beretta

School of Mathematical and Statistical Sciences Faculty Publications and Presentations

Liver cirrhosis is a leading cause of death in Hispanics and Hispanics who live in South Texas have the highest incidence of liver cancer in the United States. We aimed at determining the prevalence and associated risk factors of cirrhosis in this population. Clinical and demographic variables were extracted for 2466 participants in the community-based Cameron County Hispanic Cohort in South Texas. Aspartate transaminase to Platelet Ratio Index (APRI) was used to predict cirrhosis in Cameron County Hispanic Cohort. The prevalence of cirrhosis using APRI≥2 was 0.94%, which is nearly 4-fold higher than the national prevalence. Using APRI≥1, the overall …

Liver And Other Gastrointestinal Cancers Are Frequent In Mexican Americans, Ariana L. Garza, Kristina Vatcheva, Jen-Jung Pan, Mohammad H. Rahbar, Michael Fallon, Joseph B. Mccormick, Susan P. Fisher-Hoch

School of Mathematical and Statistical Sciences Faculty Publications and Presentations

Background

Disease patterns in Mexican-American health-disparity populations differ from larger United States populations.

Aims

Determine frequency of gastrointestinal cancers in Mexican Americans.

Methods

We analyzed self-reported data from the Cameron County Hispanic Cohort where we find high rates of risk factors for cancer: obesity (48.5%), diabetes (30.7%). Participants provided cancer histories about themselves and first and second degree relatives. Logistic regression models assessed risk factors. Frequencies of cancer sites were ranked and validated using concurrent age local cancer registry data.

Results

Among 9,249 individuals (participants and their relatives) there were 1,184 individuals with reports of cancer. Among cohort participants under …

Depression In Mexican Americans With Diagnosed And Undiagnosed Diabetes, Rene L. Olvera, Susan P. Fisher-Hoch, Douglas E. Williamson, Kristina Vatcheva, Joseph B. Mccormick

School of Mathematical and Statistical Sciences Faculty Publications and Presentations

Background: Depression and diabetes commonly co-occur; however, the strength of the physiological effects of diabetes as mediating factors towards depression is uncertain.

Method: We analyzed extensive clinical, epidemiological and laboratory data from n = 2081 Mexican Americans aged 35-64 years, recruited from the community as part of the Cameron County Hispanic Cohort (CCHC) divided into three groups: Diagnosed (self-reported) diabetes (DD, n = 335), Undiagnosed diabetes (UD, n = 227) and No diabetes (ND, n = 1519). UD participants denied being diagnosed with diabetes, but on testing met the 2010 American Diabetes Association and World Health Organization definitions of diabetes. …

Metabolic Health Has Greater Impact On Diabetes Than Simple Overweight/Obesity In Mexican Americans, Shenghui Wu, Susan P. Fisher-Hoch, Belinda M. Reininger, Kristina Vatcheva, Joseph B. Mccormick

School of Mathematical and Statistical Sciences Faculty Publications and Presentations

To compare the risk for diabetes in each of 4 categories of metabolic health and BMI. Methods. Participants were drawn from the Cameron County Hispanic Cohort, a randomly selected Mexican American cohort in Texas on the US-Mexico border. Subjects were divided into 4 phenotypes according to metabolic health and BMI: metabolically healthy normal weight, metabolically healthy overweight/obese, metabolically unhealthy normal weight, and metabolically unhealthy overweight/obese. Metabolic health was defined as having less than 2 metabolic abnormalities. Overweight/obese status was assessed by BMI higher than 25 kg/m2. Diabetes was defined by the 2010 ADA definition or by being on a diabetic …

Hepatitis C Virus In Mexican Americans: A Population-Based Study Reveals Relatively High Prevalence And Negative Association With Diabetes, Gordon P. Watt, Kristina Vatcheva, Laura Beretta, Jen-Jung Pan, Michael Fallon, Joseph B. Mccormick, Susan P. Fisher-Hoch

School of Mathematical and Statistical Sciences Faculty Publications and Presentations

This study aimed to estimate the prevalence and risk factors for hepatitis C virus (HCV) infection in Mexican Americans living in South Texas. We tested plasma for the presence of HCV antibody from the Cameron County Hispanic Cohort (CCHC), a randomized, population-based cohort in an economically disadvantaged Mexican American community on the United States/Mexico border with high rates of chronic disease. A weighted prevalence of HCV antibody of 2·3% [n = 1131, 95% confidence interval (CI) 1·2-3·4] was found. Participants with diabetes had low rates of HCV antibody (0·4%, 95% CI 0·0-0·9) and logistic regression revealed a statistically significant negative …