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Full-Text Articles in Medicine and Health Sciences
Oncolog, Volume 61, Number 11-12, November - December 2016, Brandon C. Strubberg, Sarah Bronson, Stephanie Deming, E Nielsen
Oncolog, Volume 61, Number 11-12, November - December 2016, Brandon C. Strubberg, Sarah Bronson, Stephanie Deming, E Nielsen
OncoLog MD Anderson's Report to Physicians (All issues)
- Innovative Trial Investigates Molecular Drivers of Triple-Negative Breast Cancer: A new clinical trial focusing on molecular biomarkers of triple-negative breast cancer (TNBC) is attempting to advance targeted therapy against the deadly disease.
- Smac Mimetics Show Activity against Myelofibrosis: Not all cases of myelofibrosis respond well to ruxolitinib, the only drug approved for this disease. However, early studies indicate that a new class of drugs, Smac mimetics, can achieve a response in some patients with myelofibrosis.
- Urothelial Cancer Subtypes Predict Treatment Response: Subtypes of urothelial cancer identified through gene expression profiling predict which patients are most likely to respond to neoadjuvant …
Oncolog, Volume 61, Number 10, October 2016, Laura L. Russell, Joe Munch, Bryan Tutt, Z Ahmed
Oncolog, Volume 61, Number 10, October 2016, Laura L. Russell, Joe Munch, Bryan Tutt, Z Ahmed
OncoLog MD Anderson's Report to Physicians (All issues)
- Preventing Postoperative Urinary Tract Infections in Cancer Patients: Urinary tract infections (UTIs) increase morbidity, mortality and health care costs and prolong hospitalizations for patients who require urinary catheters-especially those who undergo long, complex surgeries or procedures to treat urological or gynecological cancers. To reduce the incidence of UTIs, clinicians at The University of Texas MD Anderson Cancer Center developed a quality improvement program for surgical patients at the institution.
- Study Offers a Starting Point for Testing Immunotherapy in Rectal Cancer Patients with Deficient DNA Mismatch Repair: A recent study's findings provide a starting point for assessing the efficacy of immunotherapy …
Oncolog, Volume 61, Number 08, August 2016, Joe Munch, Bryan Tutt, E Nielsen
Oncolog, Volume 61, Number 08, August 2016, Joe Munch, Bryan Tutt, E Nielsen
OncoLog MD Anderson's Report to Physicians (All issues)
- Finding a Way Forward in Parathyroid Carcinoma: Among the rarest of the rare malignancies, parathyroid carcinoma poses myriad diagnostic and treatment challenges. Owing to its extreme rarity, very little is known about the mechanisms driving parathyroid carcinoma, let alone how to target them; and survival rates have not budged in decades. However researchers at The University of Texas MD Anderson Cancer Center are working to change this.
- Studies Explore Screening for HPV-related Anal and Oropharyngeal Cancers: No consensus screening guidelines exist for human papillomavirus (HPV)-related cancers other than cervical cancer. As a step toward establishing such guidelines, studies under way …
Oncolog, Volume 61, Number 07, July 2016, Bryan Tutt, Sarah Bronson, Laura Russell
Oncolog, Volume 61, Number 07, July 2016, Bryan Tutt, Sarah Bronson, Laura Russell
OncoLog MD Anderson's Report to Physicians (All issues)
- Improving Rates of Vaccination after Hematopoietic Stem Cell Transplant: Patients who have undergone a hematopoietic stem cell transplant (HSCT) for a hematological cancer usually lose the immunity they had acquired through vaccination. Although guidelines exist for vaccinating immunocompromised transplant recipients, many patients go unvaccinated or do not complete the series of vaccinations. An ongoing initiative at The University of Texas MD Anderson Cancer Center is using a multipronged approach to improve rates of vaccination after HSCT.
- Bone Loss Prevention in Patients with Cancer: Patients undergoing cancer treatment are at an increased risk of fractures because many cancer therapies tend to …
Oncolog, Volume 61, Number 06, June 2016, Jill Deisigne, Joe Munch, Kathryn Hale, B Strubberg
Oncolog, Volume 61, Number 06, June 2016, Jill Deisigne, Joe Munch, Kathryn Hale, B Strubberg
OncoLog MD Anderson's Report to Physicians (All issues)
- Proton Therapy Trials May Provide More Options for Patients with Non-Small Cell Lung Cancer: Proton therapy offers the potential to deliver a higher radiation dose to lung tumors and a lower dose to healthy tissues than does standard radiation therapy. However, the effectiveness of proton therapy has not yet been documented in clinical trials for patients with non-small cell lung cancer (NSCLC), the most common type of lung cancer. Two ongoing trials of proton therapy aim to demonstrate its effectiveness and may change the standard of care for NSCLC.
- Innovative "Basket" Trial Shows Promise of BRAF Inhibition in Various Cancers: …
Oncolog, Volume 61, Number 05, May 2016, Bryan Tutt, Katelyn Werner
Oncolog, Volume 61, Number 05, May 2016, Bryan Tutt, Katelyn Werner
OncoLog MD Anderson's Report to Physicians (All issues)
- Intratumoral Therapies Offer Novel Cancer Treatment Approach: Injecting cancer treatments such as vaccines and genetically modified bacteria and viruses directly into tumors may shrink or destroy the tumors and stimulate an immune response that attacks tumor cells. These treatments have shown promise in clinical trials, and newer trials are exploring whether such treatments can augment the effectiveness of immunotherapy in patients with metastatic or inoperable disease.
- High-Risk Acute Lymphoblastic Leukemia Subtype Targeted in Upcoming Clinical Trial: Early T cell precursor acute lymphoblastic leukemia (ETP-ALL), an uncommon subtype of T cell acute lymphoblastic leukemia (T-ALL), carries a poor prognosis and low …
Oncolog, Volume 61, Number 04, April 2016, Joe Munch, Bryan Tutt, K Werner
Oncolog, Volume 61, Number 04, April 2016, Joe Munch, Bryan Tutt, K Werner
OncoLog MD Anderson's Report to Physicians (All issues)
- Aggressive Multimodality Salvage Therapy for Locally Recurrent Rectal Cancer Offers Hope to Patients: For patients with locally recurrent rectal cancer, multimodality salvage therapy presents the only chance for a cure. Such therapy is offered at just a handful of specialized referral institutions, including The University of Texas MD Anderson Cancer Center.
- Rapid Assessment, Clinical Trials Could Improve Outcomes for Anaplastic Thyroid Cancer Patients: Anaplastic thyroid cancer is extremely aggressive-only 20% of patients survive 1 year after their diagnosis-so patients require immediate assessment and treatment. A program at The University of Texas MD Anderson Cancer Center expedites the care of patients …
Oncolog, Volume 61, Number 03, March 2016, Bryan Tutt, Sarah Bronson, Jill Deisigne, K Werner
Oncolog, Volume 61, Number 03, March 2016, Bryan Tutt, Sarah Bronson, Jill Deisigne, K Werner
OncoLog MD Anderson's Report to Physicians (All issues)
- Innovations Decrease Toxic Effects of Radiation Therapy for Mediastinal Tumors from Hematological Malignancies: Anterior mediastinal masses caused by lymphoma or leukemia can be difficult to treat because sensitive tissues in the area are vulnerable to damage from radiation therapy. To treat these tumors while sparing healthy tissue, radiation oncologists at The University of Texas MD Anderson Cancer Center use a combination of advanced technologies and new techniques.
- Transoral Robotic Surgery Enables Less Toxic Treatment of Early Throat Cancers: For decades, many patients with hard-to-reach throat cancers received high-dose radiation and chemotherapy, with their often severe toxic effects, because conventional surgery …
Oncolog, Volume 61, Number 01, January 2016, Sarah Bronson, Bryan Tutt, Bryan Tutt
Oncolog, Volume 61, Number 01, January 2016, Sarah Bronson, Bryan Tutt, Bryan Tutt
OncoLog MD Anderson's Report to Physicians (All issues)
- Proactive Management of Li-Fraumeni Syndrome Benefits Patients: Li-Fraumeni syndromes a hereditary disorder that confers an extremely high likelihood of developing cancer on affected individuals.
- Clinical Trial Tests High-Dose Radiation Therapy for Limited Stage Small Cell Lung Cancer: Small cell lung cancer carries a poor prognosis, even for patients without metastatic disease. But a phase III trial of high-dose daily or accelerated twice-daily thoracic radiation therapy for limited stage small cell kung cancer may lead to longer survival.
- Reducing Complications and Hospital Readmissions after Liver Surgery: Hepatectomy carries a risk of complications that can lead to hospital readmission and even death. …