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Full-Text Articles in Medicine and Health Sciences

Dopaminergic Modulation Of Medial Prefrontal Cortex Deactivation In Parkinson Depression, Anders H. Andersen, Charles D. Smith, John T. Slevin, Richard J. Kryscio, Catherine A. Martin, Frederick A. Schmitt, Lee X. Blonder Nov 2015

Dopaminergic Modulation Of Medial Prefrontal Cortex Deactivation In Parkinson Depression, Anders H. Andersen, Charles D. Smith, John T. Slevin, Richard J. Kryscio, Catherine A. Martin, Frederick A. Schmitt, Lee X. Blonder

Neuroscience Faculty Publications

Parkinson's disease (PD) is associated with emotional abnormalities. Dopaminergic medications ameliorate Parkinsonian motor symptoms, but less is known regarding the impact of dopaminergic agents on affective processing, particularly in depressed PD (dPD) patients. The aim of this study was to examine the effects of dopaminergic pharmacotherapy on brain activation to emotional stimuli in depressed versus nondepressed Parkinson disease (ndPD) patients. Participants included 18 ndPD patients (11 men, 7 women) and 10 dPD patients (7 men, 3 women). Patients viewed photographs of emotional faces during functional MRI. Scans were performed while the patient was taking anti-Parkinson medication and the day after …


Homelessness As A Determinant Of Health Disparities Between Young Gay And Bisexual Males In Chicago, Jaclyn M. Shea, Douglas Bruce May 2015

Homelessness As A Determinant Of Health Disparities Between Young Gay And Bisexual Males In Chicago, Jaclyn M. Shea, Douglas Bruce

DePaul Discoveries

There is limited research documenting health disparities between gay and bisexual males. This study aimed to examine the health behaviors and outcomes of young gay and bisexual males in Chicago, including substance use, mental health, and homelessness. Data was from a cross-sectional survey of 180 bisexual and gay males age 16-24. Bivariate results indicate that bisexual males experience higher rates of homelessness, daily marijuana use, depressive symptoms, lifetime gonorrhea and chlamydia. Logistic regression results reveal homelessness was significantly associated with marijuana use, gonorrhea, chlamydia, and depressive symptoms. Research on disparities within sexual minorities and homelessness are needed to better understand …


The Psychological Response To A Low Carbohydrate Ketogenic Diet In Combination With A Six-Week Strength Training Protocol, Matthew T. Thorp May 2015

The Psychological Response To A Low Carbohydrate Ketogenic Diet In Combination With A Six-Week Strength Training Protocol, Matthew T. Thorp

Masters Theses, 2010-2019

The aim of the present study was to determine whether or not long-term adherence to a Low-Carbohydrate Ketogenic Diet (LCKD) combined with a powerlifting strength training protocol could produce a positive psychological response. This six-week randomized control trial consisted of a treatment (LCKD) group (7% carbohydrates, 50% fat and 45% protein) and a control (CON) group (ad libitum). Both groups completed a validated powerlifting training protocol, as well as the Hospital Anxiety and Depression Scale and the Profile of Mood States. Multivariate testing and general linear modeling statistical analyses were used to compare psychological response between groups (p < 0.05) and found that there was a significant decrease in anxiety over the duration of six-weeks among both groups. No other psychological responses, including negative responses, were found to be significant. All participants significantly improved one-repetition max bench press, back squat, and deadlift (p < 0.05). The main findings of this study suggest that some positive psychological responses exist from long-term LCKD adherence, as well as potential increases in strength performance.


Maternal Obesity And Incidence Of Depression, Caroline A. Habjan May 2015

Maternal Obesity And Incidence Of Depression, Caroline A. Habjan

Honors Capstone Projects - All

Obesity is a national epidemic in the United States, which both directly and indirectly affects the social productivity of individuals, the American macro economy and individuals’ personal health and well being. Depression often interferes with an individual’s ability to work, sleep, study, eat, and enjoy life. A maternal state of both obesity and depression may cause serious adverse medical conditions in the mother’s child. Taking steps to treat depression and obesity are critical in the construct of modern medicine. This project yields results that have the potential to make treatment options better tailored, more efficient, effective and economically-sound for the …


Drink Like A Lawyer: The Neuroscience Of Substance Use And Its Impact On Cognitive Wellness, Debra S. Austin Apr 2015

Drink Like A Lawyer: The Neuroscience Of Substance Use And Its Impact On Cognitive Wellness, Debra S. Austin

Sturm College of Law: Faculty Scholarship

Lawyers suffer from higher levels of anxiety and depression than the rest of the population, but most do not enter law school with these mental health issues. Disciplinary actions against attorneys involve substance abuse 50 to 75 percent of the time. However, neuroscience research has shown that both the brain and the genes enjoy the power of plasticity, which means that personal choices and environments shape the development of lawyers throughout their lives. Legal educators need a better understanding of what aspects or characteristics of legal education contribute to the decline in mental health of law students, lawyers, and judges, …


Aerobic And Resistance Training Improves Mood State Among Adults Living With Hiv., Jason R. Jaggers, Gregory A. Hand, Wesley D. Dudgeon, Stephanie Burgess, Kenneth D. Phillips, Larry Durstine, Steven N. Blair Jan 2015

Aerobic And Resistance Training Improves Mood State Among Adults Living With Hiv., Jason R. Jaggers, Gregory A. Hand, Wesley D. Dudgeon, Stephanie Burgess, Kenneth D. Phillips, Larry Durstine, Steven N. Blair

Faculty Scholarship

The purpose of this investigation was to examine the effects of combined aerobic and resistance exercise training among self-reported mood disturbances, perceived stress, frequency of self-reported symptoms, and symptom distress in a sample of HIV+ adults. For this purpose, 49 participants were randomly assigned into an exercise (EX) or control (CON) group. Those in the EX group completed 50 min of supervised aerobic and resistance training at a moderate intensity twice a week for 6 weeks. The CON group reported to the university and engaged in sedentary activities. Data were collected at baseline before randomization and 6 weeks post intervention. …