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Protective Effect Of \Beta-Glucan On Acute Lung Injury Induced Bylipopolysaccharide In Rats, Meryem Iraz, Mustafa Iraz, Mukaddes Eşrefoğlu, Mehmet Şeri̇f Aydin
Protective Effect Of \Beta-Glucan On Acute Lung Injury Induced Bylipopolysaccharide In Rats, Meryem Iraz, Mustafa Iraz, Mukaddes Eşrefoğlu, Mehmet Şeri̇f Aydin
Turkish Journal of Medical Sciences
Background/aim: Lipopolysaccharide (LPS)-induced endotoxemia can cause serious organ damage such as acute lung injury and death by triggering the secretion of proinflammatory cytokines and acute-phase reactants. The goal of this study was to evaluate the effects of \beta-glucan on inflammatory mediator levels and histopathological changes in LPS-induced endotoxemia. Materials and methods: Forty-seven male Wistar albino rats were randomly allocated into four groups as follows: control group, LPS group (10 mg/kg LPS), LPS + \beta-glucan group (100 mg/kg \beta-glucan before LPS administration), and \beta-glucan group. Twelve hours after LPS administration, lung and serum samples were collected. Concentrations of IL-6, IL-8, C-reactive …
Serum Lp-Pla2: As A Novel Viewpoint In Periodontal Treatment Of Hyperlipidaemics, Özlem Fentoğlu, Fatma Yeşi̇m Kirzioğlu, Memduha Tözüm Bulut, Şi̇vge Kurgan, Havva Koçak, Recep Sütcü, Banu Kale Köroğlu, Meral Günhan
Serum Lp-Pla2: As A Novel Viewpoint In Periodontal Treatment Of Hyperlipidaemics, Özlem Fentoğlu, Fatma Yeşi̇m Kirzioğlu, Memduha Tözüm Bulut, Şi̇vge Kurgan, Havva Koçak, Recep Sütcü, Banu Kale Köroğlu, Meral Günhan
Turkish Journal of Medical Sciences
Background/aim: To evaluate the effects of periodontal treatment on serum lipoprotein-associated phospholipase A2 (Lp-PLA2) and C-reactive protein (CRP) levels in hyperlipidaemic patients with periodontitis. Materials and methods: The study included 52 hyperlipidaemics and 28 systemically healthy controls (C) with periodontitis. Of the 52 hyperlipidaemics, 29 received a suggested diet (HD), and 23 of them were prescribed statin (HS). Clinical periodontal parameters, serum lipids, Lp-PLA2, and CRP levels were assessed at the baseline and 2 months after the completion of the nonsurgical periodontal treatment (2MPT). Serum parameters were also evaluated 1 week following the periodontal treatment (1WPT). Results: At the baseline, …