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Full-Text Articles in Medicine and Health Sciences
Characterizing The Neuropeptide Pathways Between The Forebrain And The Pons., Ali Al-Magableh
Characterizing The Neuropeptide Pathways Between The Forebrain And The Pons., Ali Al-Magableh
Electronic Theses and Dissertations
Many current health problems including obesity, hypertension, stroke, heart disease, and type 2-diabetes can be attributed to diet. One powerful determinant of food selection is how good or bad a food 'tastes' (e.g. affective value), and is ranked highly by consumers as their top reason for choosing a food (e.g. preference). Learning plays an important role in the establishment and strengthening of food preference and, thus in guiding food choice and calories consumed. The basis of such learning is provided, in part, by limbic system modulation of gustatory neural processing at lower levels in the medulla and pons. I hypothesize …
Glycine Receptor Alpha Subunit (Glyra) Specific Inhibition Contributes To Ganglion Cell Signaling In Mouse Retina., Chi Zhang
Electronic Theses and Dissertations
In the retina, numerous types of neurons are wired together in a highly specific albeit complex pattern. This sophisticated retinal network allows extraction and encoding of more than 20 representations of the visual scene in its output neurons, the retinal ganglion cells (RGCs). Within the inner plexiform layer (IPL) of retina, glycine receptors (GlyRs) are expressed on different cell classes and modulate RGC visual activity to light onset (ON RGCs) and to light offset (OFF RGCs), for example, their temporal precision and gain control. There are four GlyR alpha subunits (GlyRα1-4) with differential expression patterns in IPL. Each mediates spontaneous …