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The Human Intruder Test: An Anxiety Assessment In Rhesus Macaques (Macaca Mulatta), Emily J. Peterson Nov 2015

The Human Intruder Test: An Anxiety Assessment In Rhesus Macaques (Macaca Mulatta), Emily J. Peterson

Masters Theses

The human intruder test (HIT) is a noninvasive tool widely used for assessing anxiety in rhesus macaques (Macaca mulatta). This thesis explores the HIT procedure and applies it to a population of monkeys with a self-injurious behavioral pathology. Individual variation on this test can be used to assess anxiety and temperament. The first experiment of this thesis applied two different procedures of the HIT to 17 monkeys at UMass. Monkeys displayed little response to the intruder, and no significant differences were detected for the two procedures. To determine whether these responses were unique to the UMass monkeys, their …


Differential Microglial Activation Following Immune Challenge In Peripubertal And Adult Outbred Mice, David J. Placzek Jul 2015

Differential Microglial Activation Following Immune Challenge In Peripubertal And Adult Outbred Mice, David J. Placzek

Masters Theses

Pubertal development is a time of growth and development in the brain, leading to high sensitivity during this period. Past research in our lab has shown that shipping female inbred and outbred mice during pubertal development alters their sensitivity to steroid hormones in adulthood, thus affecting sexual receptivity, cognition, depression-like behavior, and anxiety-like behavior. Here, we test the hypothesis that mice treated with lipopolysaccharide during pubertal development would have more active microglia, the brain's immune cells, after injection than mice treated with lipopolysaccharide in adulthood. No significant interactions were observed between treatment and age between any brain area measured, suggesting …


Associations Between Alexithymia And Executive Function In Younger And Older Adults, Gennarina Diane Santorelli Jul 2015

Associations Between Alexithymia And Executive Function In Younger And Older Adults, Gennarina Diane Santorelli

Masters Theses

The prevalence of alexithymia, a condition characterized by difficulties identifying and verbalizing one’s emotions, increases across the lifespan, with older adults reporting greater alexithymic features than young and middle-aged adults. This late-life increase in alexithymia may be the product of age-related decline in prefrontal brain circuitry implicated in emotional awareness and executive processes, notably in the anterior cingulate cortex (ACC). There is a dearth of research on the link between executive function and alexithymia in healthy adults. This study determined associations between alexithymia and executive function in healthy younger and older adults. Higher alexithymia scores were predicted to be associated …


Sleep Hygiene Practices: A Cross Cultural Survey Of Sleeping And Dreaming In College Students, Ivan Noe Martinez Salazar Jun 2015

Sleep Hygiene Practices: A Cross Cultural Survey Of Sleeping And Dreaming In College Students, Ivan Noe Martinez Salazar

Masters Theses

There is consensus that a sizeable percentage of people in most developed countries do not obtain adequate amounts or quality of sleep. These disruptions in sleep, when chronic and severe, can lead to psychological, behavioral and health consequences. The focus on behavioral and contextual factors that impact sleep has been termed “sleep hygiene”. An on-line anonymous survey collected sociodemographic information, as well as self-reports on sleep, sleep hygiene practices and dreaming across two cultural groups (English & Spanish speaking responders). A total of 204 participants (majority of them college and graduate students) answered the survey. Both cultural groups, English and …


Individualized Cognitive Rehabilitation For Adults With Acquired Brain Injury, Emily M. Aiken May 2015

Individualized Cognitive Rehabilitation For Adults With Acquired Brain Injury, Emily M. Aiken

Masters Theses

Acquired Brain Injury (ABI) can result from internal factors (e.g. tumor) or external causes (e.g. trauma). Three case studies of Korsakoff’s syndrome, meningioma, and traumatic brain injury (TBI), will be presented to illustrate the variety of cognitive deficits across different individuals with ABI. This study uses cognitive rehabilitation therapies to target individual cognitive symptoms. Results and discussion place emphasis on the use of prospective memory (PM) training for treating Korsakoff’s syndrome. The Memory for Intentions Screening Test (MIST) served as the assessment for PM analysis pre and post rehabilitation. The data from this study will be used as a model …


The Validity Of The Obsessive-Compulsive Syndromes As Emotional Disorders, Doty Jennings Jan 2015

The Validity Of The Obsessive-Compulsive Syndromes As Emotional Disorders, Doty Jennings

Masters Theses

Recent changes to the Diagnostic and Statistical Manual of Mental Disorders have grouped together syndromes which are referred to as the obsessive-compulsive spectrum (OCS). The grouping of these syndromes is disputed because of lack of empirical verification for an organization purportedly based on research that supports similarity of observed symptoms. The taxonomy of emotional disorders was tested as an alternative model. Consistent with the model of the emotional disorders, this empirical research tested two proposed characteristics. The first was whether three OCS syndromes (hoarding syndrome, body dysmorphic syndrome, and obsessive compulsive syndromes) shared the broad factor of neuroticism or negative …