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Full-Text Articles in Medicine and Health Sciences
Autoimmune Thyroiditis: A Look Into Hashimoto’S Disease, Jessica Hannan
Autoimmune Thyroiditis: A Look Into Hashimoto’S Disease, Jessica Hannan
Nursing Student Class Projects (Formerly MSN)
Thyroid disease is a general term utilized to describe a variety of conditions affecting the thyroid gland, including hypothyroidism, the deficient production of thyroid hormone; hyperthyroidism, the excess production of thyroid hormone; and goiter, the physiologic swelling of the thyroid gland (Cihakova, 2001; Warren, 2014). Primary hypothyroidism is the most prevalent thyroid disease in the United States, most frequently occurring as a result of chronic autoimmune thyroiditis, specifically Hashimoto’s Disease (Warren, 2014). Hashimoto’s disease (HD), also known as Hashimoto’s thyroiditis and human autoimmune thyroiditis, was named after Hakaru Hashimoto, a Japanese medical scientist who first described the condition in 1912 …
C-Reactive Protein, Autoimmunity, And Inflammation In The Central Nervous System, Tyler T. Wright
C-Reactive Protein, Autoimmunity, And Inflammation In The Central Nervous System, Tyler T. Wright
All ETDs from UAB
C-reactive protein (CRP) is an acute phase reactant whose blood concentration rises in response all types of inflammation. And while CRP is widely used as a clinical marker of inflammation, it has several biological functions, e.g. activation of the classical complement cascade and binding Fcγ receptors in order to mediate multiple immune processes. The full extent of CRP’s physiological activities has not yet been fully elucidated, but there is significant evidence to establish that CRP plays an important role in the onset and progression of autoimmune disease. Seminal work from our lab showed that human CRP, hepatically expressed in transgenic …