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Full-Text Articles in Medicine and Health Sciences

Low Cost Shear And Pressure Sensor, Kyle L. Rohrig, Phaethon D. Kotantoulas, Brandon J. Lloyd, Hazim H. Abualola, Tao Ruan Jan 2015

Low Cost Shear And Pressure Sensor, Kyle L. Rohrig, Phaethon D. Kotantoulas, Brandon J. Lloyd, Hazim H. Abualola, Tao Ruan

Williams Honors College, Honors Research Projects

Elevated pressure and shearing stresses at the foot-shoe interface are believed to play a role in diabetic foot ulceration. The main goal of this project was to design a simple insole that could distinguish between sites of high pressure and sites of excessive shearing stresses at the foot-shoe interface. Wear patterns that relate specifically to shear and pressure acting on the plantar surface of a patient’s foot also needed to be exhibited. The team used reflective tape that was applied to the surface to various types of insoles to look for visible wear patterns. These wear patterns were identified by …


The Effects Of Instructional Strategies On Adherence To A Flexibility Program And Physiological Outcomes, Taylor M. Graham Jan 2015

The Effects Of Instructional Strategies On Adherence To A Flexibility Program And Physiological Outcomes, Taylor M. Graham

Williams Honors College, Honors Research Projects

Health care professionals construct exercise prescriptions for clients and patients to complete on their own. Exercise specialists, physical therapists, occupational therapists, and exercise physiologists are all considered health care professionals for this study. Furthermore, the importance of flexibility and stretching is commonly overlooked. The purpose of this research study was to compare whether or not different instructional techniques affect adherence to a stretching routine, and if followed were improvements gained in quadriceps and hamstring flexibility. Thirty-one students from The University of Akron between the ages of 18 and 37 with an average height of 66.7 inches and average weight of …


Drug Interactions With Glutaredoxin Orthologues, Kahlilah R. Napper, Thomas C. Leeper, Ram Khattri, Daniel Morris, Caroline Davis Jan 2015

Drug Interactions With Glutaredoxin Orthologues, Kahlilah R. Napper, Thomas C. Leeper, Ram Khattri, Daniel Morris, Caroline Davis

Williams Honors College, Honors Research Projects

Glutaredoxin, an enzymatic protein, is an important component of cell viability and function. It catalyzes reactions involved in DNA synthesis and innate immunity [1,4]. Glutaredoxin is also essential in antibiotic resistance in pathogenic bacterial species. Pseudomonas aeruginosa in particular is responsible for infecting the lung tissue of its human hosts, resulting in the development of pneumonia and cystic fibrosis [3]. Because glutaredoxin is pertinent in cell proliferation of eukaryotic and bacterial cells alike, medicinal fragments that take advantage of the subtle differences in protein structure of the orthologous proteins can be synthesized and enhanced to bind bacterial glutaredoxins, without inhibiting …