Medicine and Health Sciences Commons^™

Pain Assessment And Possible Mechanism Of Delayed Onset Muscle Soreness, Wing Yin Lau

Theses: Doctorates and Masters

Muscle pain is felt during exercise or daily activities for several days after performing unaccustomed exercise, which is referred to as delayed onset muscle soreness (DOMS). Many people experience DOMS, but its underlying mechanisms are not fully understood. One of the challenges in the investigation of DOMS is its subjective nature, which makes the assessment ambiguous, thus establishing a standardised protocol is necessary. The present thesis scrutinised muscle pain assessments (Study 1, Study 2), developed a new assessment of muscle pain focusing on muscle fascia (Study 3), and investigated why DOMS is reduced after the second than the first bout …

Evolutionary Approaches For Feature Selection In Biological Data, Vinh Q. Dang

Theses: Doctorates and Masters

Data mining techniques have been used widely in many areas such as business, science, engineering and medicine. The techniques allow a vast amount of data to be explored in order to extract useful information from the data. One of the foci in the health area is finding interesting biomarkers from biomedical data. Mass throughput data generated from microarrays and mass spectrometry from biological samples are high dimensional and is small in sample size. Examples include DNA microarray datasets with up to 500,000 genes and mass spectrometry data with 300,000 m/z values. While the availability of such datasets can aid in …

Homebirth In Wa: Why Women Make This Choice, Colleen Ball

Theses: Doctorates and Masters

Background: Homebirths in Western Australia (WA) account for approximately 0.8% of all births. Two consecutive reports from the Perinatal and Infant Mortality Monitoring Committee found increased rates of perinatal mortality in homebirths and recommended a prospective cohort study to assess mortality and morbidity outcomes for women with planned home births in WA. The Homebirth in WA Study, of which this thesis is a component, has been funded by a directed research grant.

Aim: The aim of this study was to explore the specific reasons why women in WA choose homebirth. Research on homebirths is focused on perinatal outcomes and …

Neuromuscular Factors Affecting Stretch-Induced Torque Loss, Gabriel Siqueira Trajano

Theses: Doctorates and Masters

The mechanisms underpinning the immediate torque loss induced by acute, static muscle stretching are still not clear. The current research was designed to examine the neuromuscular factors influencing this torque loss. In Study 1, the contributions of central versus peripheral factors to the stretch-induced torque loss were investigated. Measures of central drive, including the EMG amplitude normalised to the muscle compound action potential amplitude (EMG:M), percent voluntary activation (%VA) and first volitional wave amplitude (V:M), and measures of peripheral function, including the twitch peak torque and 20:80 Hz tetanic torque ratio were made before, and immediately and 15 min after …

Identification Of Plasma Lipid Biomarkers In Alzheimer's Disease, Rhona Creegan

Theses: Doctorates and Masters

Alzheimer’s disease (AD), the commonest form of dementia, is a chronic, progressive neurodegenerative disease which manifests clinically as a slow global decline in cognitive function, including deterioration of memory, reasoning, abstraction, language and emotional stability, culminating in a patient with end-stage disease, totally dependent on custodial care. With an ageing population, there is predicted to be a marked increase in the number of people diagnosed with AD in the coming decades, making this a significant challenge to socio-economic policy and aged care. Currently there is no cure for AD and while current therapies may temporarily ameliorate symptoms, death usually occurs …

Understanding And Building Resilience With Art: A Socio-Ecological Approach, Meagan Shand

Theses: Doctorates and Masters

Resilience is a widely researched phenomenon, it means different things to different people and is perceived and measured according to the theoretical lens being applied. The following thesis reviews the theoretical development of resilience that has led to contemporary understandings, to establish a platform for the research topic - understanding and building resilience with Art. Narrative research methods are combined with art processes to illuminate the stories of eight culturally diverse women participating in a community based mental health art program, in Western Australia. Fifteen resilience themes emerged from the collective experience, and are presented in a socio-ecological framework to …

The Creation And Validation Of A Youth Fundamental Hitting Scale: The Assessment Of Youth Baseball And Softball Hitting Fundamentals And The Perceived Psychological Barriers To Hitting A Pitched Ball, Andrew Walsh

Theses: Doctorates and Masters

The primary purpose of the thesis was to create a hitting scale for youth players that assess the fundamentals of a baseball swing. Secondly, the purpose of this thesis was to determine the interactions between the changes in anxiety, perceived competence and fear variables have with actual hitting competence over a four week sport specific training program.

Acute Physiological Effects And Perceived Enjoyment Of A Single Bout Of Aerobic Interval And Continuous Moderate-Intensity Cycling In Overweight And Obese Individuals, Fujie Koh

Theses: Doctorates and Masters

Aerobic interval training, a form of high intensity interval training, is commonly prescribed to both the general and clinical populations. However, the acute physiological effects from a single bout of aerobic interval session are not fully understood. In training studies, these acute physiological effects may confound actual training adaptations when they occur following the final training session [1]. Furthermore, while recreationally active men perceived aerobic interval training to be more enjoyable than continuous moderate-intensity exercise [2], the preference of overweight and obese individuals has not been extensively researched. Since overweight and obese individuals tend to have lower exercise tolerance, it …

Relative Importance And Plasticity Of Anatomical And Neuromuscular Factors Affecting Joint Torque Production, Joanne C. Trezise

Theses: Doctorates and Masters

The present research aimed to determine (i) the relative influence anatomical and neuromuscular variables on maximal isometric, concentric and eccentric knee extensor torque (Study 1); (ii) whether the change in strength following a 10-week strength training program is associated with changes in specific anatomical and neuromuscular variables (Study 2a); (iii) whether anatomical and neuromuscular adaptations are dependent on their pre-training magnitudes; and (iv) whether it is possible to ‘predict’ an individual’s adaptation to strength training based on their anatomical and neuromuscular pre-training magnitudes (Study 2b).

The variables assessed throughout the studies include muscle cross-sectional area (CSA), fascicle length and angle …

Developing Effective Hospital Management Information Systems: A Technology Ecosystem Perspective, Christopher Bain

Theses: Doctorates and Masters

This thesis presents the results of the program of research performed in the completion of a Doctor of Philosophy (Business) entitled: Developing Effective Hospital Management Information Systems: A Technology Ecosystem Perspective.

The central contention of this thesis is that the current ecosystem models in the information technology (IT) and information systems (IS) literature can be extended and improved. In turn they can be better applied to the field of IS and the development and implementation of information systems. This research seeks to highlight an example of how these models can be extended, through an analysis of the specific context of …

Impact Of Nutrition On Cognition And Its Association With Blood And Brain Alzheimer Disease Related Biomarkers, Samantha Gardener

Theses: Doctorates and Masters

Alzheimer’s disease (AD), the most common form of senile dementia, currently affects over 35 million people worldwide. While there is no cure or effective treatment, early intervention programs hold considerable promise. Following particular dietary patterns represents one potential intervention strategy accessible to all.

Results from previous studies investigating the association of diet, cognition and biomarkers of AD are inconsistent: Positive results have been reported (1-7), whilst others have shown no associations. Prior to this thesis, no study has assessed the relationship of four dietary patterns to cognition, blood-based and neuroimaging biomarkers of AD in a large highly-characterised ageing cohort. Participants …

A Series Of Studies Examining The Development Of Sprint Speed And Momentum Of International Rugby Union Players, Matthew John Barr

Theses: Doctorates and Masters

Sprinting speed is a highly valued physical ability in rugby. There is little research examining sprinting biomechanics in rugby players and it is unclear the extent that sprinting speed and sprint momentum can even be improved in highly trained rugby players and how different speed and strength training methods might help improve it. This thesis consists of 6 studies that examine the sprinting biomechanics of elite rugby players, how strength and power training might improve sprinting speed and the potential for elite rugby players to make further improvement in their sprinting speed and sprint momentum.

Key biomechanical factors were that …

Factors That Influence The Decision-Making Of An Integrated Rehabilitation Team When Choosing A Post-Hospital Discharge Destination For Survivors Of Stroke, Jessie M. Johnson

Theses: Doctorates and Masters

Stroke is one of the more disabling conditions which may result in the inability for survivors to care for themselves independently. Stroke survivors benefit most when they receive early onset assessment, treatment, and rehabilitation. Increasingly, stroke care in Canadian hospitals relies on an interdisciplinary rehabilitation team approach to provide immediate rehabilitation services and to make decisions about discharge destination for stroke survivors. Currently, there is little research on how interdisciplinary rehabilitation teams decide upon rehabilitation placements for stroke survivors or how individuals on the team, stroke survivors, or their families participate in and contribute to this decision. This research studied …

Lower Limb Fatigue Asymmetry Of Preferred And Non-Preferred Legs After A Repeated-Sprint Test In Football Players With Previous Hamstring Injury, Cameron Lord

Theses: Doctorates and Masters

Football is the most widely played sport in the world and is thus associated with the highest total number of injuries of all sports. 12% of all football injuries are to the hamstrings, as this muscle group is subjected to constant stress during training and match play performance (Ekstrand, Hägglund, Waldén, 2011; Woods, Hawkins, Maltby, Hulse, Thomas & Hodson, 2004). While the influence of limb dominance has been extensively examined as a risk factor for injury in upper limb-dominant sports (e.g. badminton, tennis and baseball), little research has focussed on the dominance in the lower limbs. Since almost all footballers …

An Investigation Of Technique And Equipment Factors Associated With Clubhead Speed In Golf, Christopher Joyce

Theses: Doctorates and Masters

If golfers achieve long hitting distances whilst maintaining their accuracy they will gain a competitive advantage. To increase hitting distance, faster clubhead speed is required and this can potentially be achieved through a number of factors. Firstly, anthropometric factors such as height and physical factors such as trunk rotational power have been previously considered to be of importance. However, biomechanical factors such as; the X-factor (separation of the trunk-pelvis alignment when viewed in the transverse plane), have been a major focus of recent research. Further, the interaction of the golfer with the implement they hit with i.e. the golf club …

The Distinct Contributions Of Affective Distress And Personality To Memory Complaints Made In Older Adulthood, Matthew Robert Merema

Theses: Doctorates and Masters

Whilst a substantial amount of research has investigated the role of affective distress and features of personality in memory complaints made by older adults, little effort has been directed towards understanding their distinct contributions to complaints. Given considerable overlap between affective distress and features of personality, such evidence is necessary to inform theoretical frameworks pertaining to memory complaints and clarify results from other empirical studies examining these concepts. Consequently, the current study examined symptoms of depression and anxiety as predictors of memory complaints within the context of features of personality and other relevant contextual variables (i.e., age, gender, education, premorbid …

The Impact Of Implementing A Sudden Infant Death Syndrome Education Package In Jordan, Shereen Hamadneh

Theses: Doctorates and Masters

Background: Sudden Infant Death Syndrome (SIDS) is a problem worldwide. In North Jordan, SIDS rate was high as 1.32 per 1,000 live births and contributed 6% to the infant mortality rate (Bataineh, Shawagfeh, & Twalbeh, 2008). However, SIDS risk factors are preventable and can be reduced by improving knowledge and changing relevant behaviours of parents and healthcare providers (American Academy of Pediatrics, 2013; American SIDS Institute, 2011; Bataineh, Hussein Shawagfeh, & Twalbeh, 2008; Bredemeyer, 2004; Grazel, Phalen, & Polomano, 2010b; Moon, Oden, & Grady, 2004; NICHD, 2010). Still educating Jordanians about SIDS has not been a national health policy priority. …

An Investigation Into Dust, Gases And Vapours Expulsed During The Oxidation Of Pyritic Black Shale, And Their Potential For Impacting On Employee Health, Tristan Lynn

Theses: Doctorates and Masters

Pyritic black shale (PBS) is occasionally extracted as a waste product of iron ore mining in the Pilbara region of Western Australia. Mineralogical studies such as Brocks, Summons, Buick, and Logan (2003) of the PBS located at Mount Tom Price Operations have established that PBS can contain elevated concentrations of pyrite, carbon, bitumens, polyaromatic hydrocarbons and volatile organic compounds (VOCs). The natural oxidative weathering of PBS can cause exothermic reactions leading to the shale reaching temperatures that cause the expulsion of toxic gases such as hydrogen sulphide, sulphur dioxide, methane and carbon monoxide.

Current management of the potential hazards of …

Doncp: Incorporating Step Two Of The Nutrition Care Process Into Hospital Dietetic Practice Using An Implementation Package, Jane Porter

Theses: Doctorates and Masters

The Nutrition Care Process (NCP) and accompanying International Dietetic and Nutrition Terminology (IDNT) has been endorsed internationally as the standard model for nutrition care. However, there is limited published Australian literature on the implementation of the NCP and IDNT including the attitudes, knowledge and support requirements of dietitians to facilitate this. This study aimed to develop and test a survey to assess attitudes, support and knowledge of NCP and use the findings in conjunction with literature to design and implement a NCP package and evaluate the package.

The research was conducted in two phases: (1) formative research to inform development …

Mechanisms Affecting Post-Activation Potentiation Following Voluntary Isokinetic Knee Extension, Laurent B. Seitz

Theses: Doctorates and Masters

The present research was designed to: 1) determine whether the voluntary PAP effects commonly observed after conditioning activity (CA; i.e. muscular contraction prior to a ‘test’ contraction) are a consequence of acute neuromuscular alterations relating to the CA itself, or whether they simply reflect warm-up and/or familiarisation effects; 2) clarify the influence of the contraction velocity, duration and total work characteristics of the CA on voluntary PAP; 3) determine the factors allowing stronger individuals to express higher level of voluntary PAP; and 4) determine the peripheral and central mechanisms of voluntary PAP in human skeletal muscle. In Study 1, the …

De Concentv Amisso Qvaerendo: An Investigation Into The Relative Benefits Of Three Different Types Of Ambient Music On The Observed Agitated Behaviour And Quality Of Life Of Dementia Sufferers In Residential Aged Care Facilities, Peter Wilkinson

Theses: Doctorates and Masters

There is an increasing body of research evidence to support the use of music as a therapeutic modality in reducing the agitated behaviour frequently associated with late-stage dementia. Although much of this evidence suggests that music interventions are most effective when they are “individualized”, this type of intervention is often difficult to implement in large, busy, aged care facilities where residents may be located together in communal areas during the day. The challenge therefore is to try and identify a particular musical genre which, when played as “ambient” or “background” music, demonstrates a consistent capacity to reduce agitated behaviour in …

Speech And Swallowing Rehabilitation In The Home: A Comparison Of Two Service Delivery Models For Stroke Survivors, Katy J. E. Stewart

Theses: Doctorates and Masters

Background and Aims

Speech and swallowing difficulties are common sequelae for people who have suffered a stroke. Recently, there has been an increase in early discharge, community rehabilitation and the use of therapy assistants to support health professionals in stroke rehabilitation. However, the impact of these factors on communication and swallowing outcomes remains under researched. This research explored Rehabilitation in the Home (RITH) Speech Pathology (SP) services for stroke survivors with dysarthria and dysphagia. More specifically, this research investigated whether traditional speech pathology interventions, supplemented with a home practice program are effective, as well as compare usual treatment to that …

Learning From The Experts: Qualitative Study Of The Lived Experience Of Mental Illness, Zdenka Bartova

Theses: Doctorates and Masters

Severe mental illness has a profound effect on the affected individuals yet it does not necessarily prevent them from leading a meaningful and fulfilling life, and therefore recovering. Recovery has received a great interest in clinical and consumer research yet little is known about how those individuals who do not primarily identify with recovery respond to the concept and come to accept it as something that is personally meaningful. Using a qualitative approach following the principles of Gadamer’s (1975) hermeneutics, the present study explored people’s subjective experience of mental illness with the aim of identifying factors related to their views …

A Mixed Methods Obesity Prevention Intervention For Australian Children Aged 6-12 Years: Influence Of Parents Misperceptions About Food And Exercise On The Efficacy Of Educational Obesity Simulations, Claire Ellen Roockley

Theses: Doctorates and Masters

Increasing numbers of Australian children are being classified as overweight or obese. Given the health complications associated with excess weight, interventions to prevent children becoming overweight are crucial. Despite literature showing that parents shape their children’s food and exercise habits, no child obesity prevention programs have directly targeted parents. Moreover, although fear appeals have been used across several health promotion areas to change attitudes and behaviours, they have not been incorporated into an obesity preventive program. This study addressed these gaps by testing whether fear-based obesity simulations, targeted at parents as a tool for preventing childhood obesity, was more effective …

The Clinical Utility Of The Halosperm Assay And The Development Of A Simplified Method Of Human Semen Storage For The Testing Of Sperm Dna Fragmentation, Ashleigh Cavell Mcevoy

Theses: Doctorates and Masters

Male infertility is typically diagnosed upon routine semen analysis following the World Health Organisation’s (WHO) semen analysis manual. Recent editions of the manual have essentially changed the diagnosis of a semen sample, prompting debate between experts as to which edition should be followed. Deoxyribonucleic Acid (DNA) integrity analysis is proving to be a useful adjunct to semen analysis as 15% of infertile men have a normal semen analysis but they have an increased DNA fragmentation level (DFL) which has been associated with increased disease incidence in any resultant offspring. However, such tests are not endorsed by the WHO, possibly due …

Plasma Insulin-Degrading Enzyme: Characterisation And Evaluation As A Potential Biomarker For Alzheimer's Disease, Michelle Tegg

Theses: Doctorates and Masters

Alzheimer’s disease (AD) is increasing in prevalence due to increasing lifespan and altered lifestyle. It is the fourth major cause of death in Western countries, resulting in significant economic and social impact (Von Strauss, et al., 1999; Goate, 1997). There are no blood biomarkers currently accepted for the diagnosis of AD, and the identification of suitable biomarkers would eventually reduce the necessity for invasive, expensive and slow diagnostic procedures, as well as facilitate prognostic studies. An AD blood test would decrease the need for delaying diagnosis due to ambivalent presentation, and allow therapeutic intervention to commence at an earlier …

Neuromuscular Fatigue Following A Singles Badminton Match, Zengyuan Lin

Theses: Doctorates and Masters

A typical badminton singles match involves numerous intense and high impact movements. Lunges were accounted for approximately 15% of overall movements and were believed to presumably induce significant muscle damage following a match. However, no previous study has investigated changes in knee extensor muscle function after a badminton match.The present study investigated changes in knee extensor neuromuscular function and muscle soreness after a simulated 1-h badminton singles match in relation to the number of lunges performed in the match.

Ten state-level male badminton players were recruited (n=10), with each player played a total of eight simulated 1-h matches under the …

Space-Time Statistical Analysis Of Malaria Morbidity Incidence Cases In Ghana: A Geostatistical Modelling Approach, Simon K. Appiah

Theses: Doctorates and Masters

Malaria is one of the most prevalent and devastating health problems worldwide. It is a highly endemic disease in Ghana, which poses a major challenge to both the public health and socio-economic development of the country. Major factors accounting for this situation include variability in environmental conditions and lack of prevention services coupled with host of other socio-economic factors. Ghana’s National Malaria Control Programme (NMCP) risk assessment measures have been largely based on household surveys which provided inadequate data for accurate prediction of new incidence cases coupled with frequent incomplete monthly case reports. These raise concerns about annual estimates on …

Understanding And Improving Pacing Strategies During Standard Distance Triathlons In Age Group Athletes, Sam Shi Xuan Wu

Theses: Doctorates and Masters

Pacing is an integral aspect of performance during all exercise, including multi-sport events such as triathlon. However, to date, the optimal pacing strategies to adopt over an entire triathlon, as well as during each specific discipline (i.e. swim, cycle and run), is not well understood. Therefore, the primary purpose of this thesis was to identify and understand current pacing strategies adopted by highly performing triathletes across different triathlon distances. This research aids in identifying pacing strategies that may improve overall performance during triathlon.

In the first study, the influence of sex and race distance on the age-related declines in the …

Role Of Physical Exercise In Reducing Depression And Improving Mental Health In Cancer Survivors, Gregory Levin

Theses: Doctorates and Masters

Cancer survivors are more than twice as likely as the general population to suffer the debilitating effects of depression. This comorbid condition is associated with several negative consequences, such as reduction in compliance with cancer treatments, and hastened mortality. Recent research has examined the therapeutic effect of exercise on depression and reported excellent results of similar magnitude to those achieved with pharmacotherapy or psychological intervention. However, no research, to date, has examined the effectiveness of exercise on reducing depression in depressed cancer survivors. In order to address this important question this thesis reviewed previous literature in the area of cancer …