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Full-Text Articles in Medicine and Health Sciences
Pgc-1Α Mediated Muscle Aerobic Adaptations To Exercise, Heat And Cold Exposure, Mohammed Ihsan, Greig Watson, Chris R. Abbiss
Pgc-1Α Mediated Muscle Aerobic Adaptations To Exercise, Heat And Cold Exposure, Mohammed Ihsan, Greig Watson, Chris R. Abbiss
Research outputs 2014 to 2021
PGC-1α is regarded as a key regulator of mitochondrial biogenesis due to its central role in regulating the activity of key transcription factors associated with encoding mitochondrial components. Additionally, PGC-1α has shown to mediate adaptations that increase fat metabolism and angiogenesis, contributing to the overall oxidative phenotype of the muscle. While it is well established that exercise is a potent stimulator of PGC-1α, recent evidence indicates that heat and cold exposures may also influence mitochondrial biogenesis through the up-regulation of PGC-1α. This highlights the potential use of these modalities in conjunction with exercise to enhance training adaptations. As such, the …
Iron Status And The Acute Post-Exercise Hepcidin Response In Athletes, Peter Peeling, Marc Sim, Claire E. Badenhorst, Brian Dawson, Andrew D. Govus, Chris R. Abbiss, Dorine W. Swinkels, Debbie Trinder
Iron Status And The Acute Post-Exercise Hepcidin Response In Athletes, Peter Peeling, Marc Sim, Claire E. Badenhorst, Brian Dawson, Andrew D. Govus, Chris R. Abbiss, Dorine W. Swinkels, Debbie Trinder
Research outputs 2014 to 2021
This study explored the relationship between serum ferritin and hepcidin in athletes. Baseline serum ferritin levels of 54 athletes from the control trial of five investigations conducted in our laboratory were considered; athletes were grouped according to values 100 mg/L (SF>100). Data pooling resulted in each athlete completing one of five running sessions: (1) 8x3 min at 85% vVO2peak; (2) 5x4 min at 90% vVO2peak; (3) 90 min continuous at 75% vVO2peak; (4) 40 min continuous at 75% vVO 2peak; (5) 40 min continuous at 65% vVO2peak. Athletes from each running session were represented amongst all four groups; hence, …